Patents by Inventor Berangere Avalle-Bihan

Berangere Avalle-Bihan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STAT5 inhibitors and use thereof
    Patent number: 10072266
    Abstract: Provided is a composition of matter binding specifically to STAT5, preferably to STAT5B, including a nucleic acid aptamer, and methods of treatment of cancer, and in particular leukaemia via the inhibition of STAT5 protein. The present invention relates more particularly to specific aptamers of STAT5 protein, and the therapeutic or diagnostic use thereof. Also provided is a method for detecting STAT5 in a biological sample, including contacting a nucleic acid aptamer binding specifically to STAT5 with a sample taken beforehand from a subject and determining the quantity of said aptamer bound to said sample.
    Type: Grant
    Filed: March 20, 2015
    Date of Patent: September 11, 2018
    Assignees: UNIVERSITÉ DE TECHNOLOGIE DE COMPIÈGNE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Berangere Avalle-Bihan, Claire Loussouarn, Hassan Isber, Alain Friboulet, Severine Padiolleau
  • STAT5 INHIBITORS AND USE THEREOF
    Publication number: 20170137817
    Abstract: Provided is a composition of matter binding specifically to STAT5, preferably to STAT5B, including a nucleic acid aptamer, and methods of treatment of cancer, and in particular leukaemia via the inhibition of STAT5 protein. The present invention relates more particularly to specific aptamers of STAT5 protein, and the therapeutic or diagnostic use thereof. Also provided is a method for detecting STAT5 in a biological sample, including contacting a nucleic acid aptamer binding specifically to STAT5 with a sample taken beforehand from a subject and determining the quantity of said aptamer bound to said sample.
    Type: Application
    Filed: March 20, 2015
    Publication date: May 18, 2017
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE DE TECHNOLOGIE DE COMPIEGNE
    Inventors: Berangere AVALLE-BIHAN, Claire LOUSSOUARN, Hassan ISBER, Alain FRIBOULET, Severine PADIOLLEAU
  • Compounds capable of modulating the activity and stimulating the production of a catalytic antibody
    Patent number: 7109291
    Abstract: The invention concerns novel compounds capable of modulating the activity and stimulating the production of catalytic antibodies. More particularly, the invention concerns a compound capable of increasing the activity of an antibody having specific affinity for the catalytic site of the antibody, and it is not immunogenic. Such compounds are useful in particular for therapeutic treatment or prevention of a pathology related to an enzymatic deficiency, to stimulate in vivo hydrolysis of xenobiotics, drugs, medicines or any other molecule potentially toxic for the organism or for preventing or inhibiting allergic reactions.
    Type: Grant
    Filed: November 17, 2003
    Date of Patent: September 19, 2006
    Assignee: Gradient
    Inventors: Alain Friboulet, Berangere Avalle-Bihan, Helene Debat, Daniel Thomas
  • Compounds capable of modulating the activity and stimulating the production of a catalytic antibody
    Publication number: 20040138124
    Abstract: The invention concerns novel compounds capable of modulating the activity and stimulating the production of catalytic antibodies. More particularly, the invention concerns a compound capable of increasing the activity of an antibody having specific affinity for the catalytic site of the antibody, and it is not immunogenic. Such compounds are useful in particular for therapeutic treatment or prevention of a pathology related to an enzymatic deficiency, to stimulate in vivo hydrolysis of xenobiotics, drugs, medicines or any other molecule potentially toxic for the organism or for preventing or inhibiting allergic reactions.
    Type: Application
    Filed: November 17, 2003
    Publication date: July 15, 2004
    Inventors: Alain Friboulet, Berangere Avalle-Bihan, Helene Debat, Daniel Thomas