Patents by Inventor Berhnard Kleter

Berhnard Kleter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detection and identification of human papillomavirus by PCR and type-specific reverse hybridization
    Patent number: 6482588
    Abstract: The present invention relates to a method for detection and/or identification of HPV present on a biological sample, comprising the steps of amplification of HPV polynucleic acids and of hybridization of said amplified ploynucleic acids to a number of probes. By means of PCR, a short fragment of the L1 gene of HPV is amplified. The amplimers are then contacted with probes that specifically hybridize to said short fragment of the L1 gene of either one or more than one HPV type. A preferred format is the reverse hybridization technique, more particularly the LiPA technique. The invention also relates to primers and probes to be used in a method of detection and/or identification of HPV and to a diagnostic kit to perform said method.
    Type: Grant
    Filed: March 16, 2000
    Date of Patent: November 19, 2002
    Assignee: Innogenetics S.A.
    Inventors: Leen-Jan Van Doorn, Wim Quint, Berhnard Kleter, Jan TerSchegget