Patents by Inventor Berkeley W. Cue

Berkeley W. Cue has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline 2-(1-pentyl-3-guanidino)-4-(2-methyl-4-imidazolyl) thiazole dihydrochloride trihydrate
    Patent number: 4997949
    Abstract: Crystalline 2-(1-pentyl-3-guanidino)-4-(2-methyl-4-imidazolyl)thiazole dihydrochloride trihydrate having advantageous properties.
    Type: Grant
    Filed: April 20, 1989
    Date of Patent: March 5, 1991
    Assignee: Pfizer Inc.
    Inventors: Douglas J. M. Allen, Berkeley W. Cue
  • Intermediates for preparing pirbuterol and analogs
    Patent number: 4632992
    Abstract: Processes and intermediates useful in the preparation of bronchodilator compounds of the formula ##STR1## wherein R is hydrogen, methyl or hydroxymethyl are described. Those compounds wherein R is H or CH.sub.3 have been found to have further utility as intermediates for pirbuterol (wherein R is hydroxymethyl).
    Type: Grant
    Filed: August 16, 1984
    Date of Patent: December 30, 1986
    Assignee: Pfizer Inc.
    Inventors: Berkeley W. Cue, Stephen S. Massett
  • 3-Acetoxy or benzyloxy-2-acetoxymethyl-6-[1-acetoxy-2-(N-tert-butylacetamido)ethyl]py ridine intermediates
    Patent number: 4477671
    Abstract: Processes and intermediates useful in the preparation of bronchodilator compounds of the formula ##STR1## wherein R is hydrogen, methyl or hydroxymethyl are described. Those compounds wherein R is H or CH.sub.3 have been found to have further utility as intermediates for pirbuterol (wherein R is hydroxymethyl).
    Type: Grant
    Filed: June 2, 1983
    Date of Patent: October 16, 1984
    Assignee: Pfizer Inc.
    Inventors: Berkeley W. Cue, Stephen S. Massett
  • Isatin products
    Patent number: 4186132
    Abstract: An aniline is converted to a 3-lower hydrocarbonthiooxindole by processes already known in the art, the product converted to a 3-halo-3-lower hydrocarbonthiooxindole by oxidative halogenation, and the product subjected to hydrolysis to form the desired isatins.
    Type: Grant
    Filed: April 15, 1977
    Date of Patent: January 29, 1980
    Assignee: The Regents of the University of Minnesota
    Inventors: Paul G. Gassman, Berkeley W. Cue
  • 1,4-Dioxo- and 4-oxoquinoxaline-2-carboxaldehyde sulfonylhydrazones and certain derivatives thereof
    Patent number: 4100284
    Abstract: The invention relates to novel chemical compounds which have useful antibacterial properties and are also of value in promoting animal growth and improving animal feed efficiency. More specifically, these new chemical compounds are certain sulfonylhydrazones of 1,4-dioxoquinoxaline-2-carboxaldehyde, 4-oxoquinoxaline-2-carboxaldehyde and certain derivatives thereof of formula (I): ##STR1## wherein A is N or N .fwdarw. O; R is a member selected from the group consisting of alkyl having from one to five carbon atoms, trifluoromethyl, phenyl, npahthyl, benzyl, styryl and phenyl substituted by up to two members selected from the group consisting of Cl, F, Br, CH.sub.3, CH.sub.3 O and NO.sub.2 ; R.sup.1 is hydrogen or methyl; R.sup.2 is hydrogen or methyl; R.sup.3 is a 6- or 7-position substituent and is selected from the group H, Cl, CH.sub.3, CH.sub.3 O, SO.sub.2 NH.sub.2, SO.sub.2 NHCH.sub.3 and SO.sub.2 N(CH.sub.3).sub.2 ; R.sup.4 is a 7- or 6-position substituent and is selected from the group H, Cl and CH.
    Type: Grant
    Filed: January 18, 1977
    Date of Patent: July 11, 1978
    Assignee: Pfizer Inc.
    Inventor: Berkeley W. Cue