Patents by Inventor Berma M. Kinsey

Berma M. Kinsey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Macroaggregated protein conjugates as oral genetic immunization delivery agents
    Patent number: 6821955
    Abstract: This invention relates to the development of an expression vector containing an antigenic genomic sequence, which is bound to an aggregated protein-polycationic polymer conjugate. More particularly it relates to the use of the expression vector as an oral DNA vaccine or to induce immune response. In specific embodiments, the expression vector is bound to a protein-polycationic polymer suspension.
    Type: Grant
    Filed: April 6, 2001
    Date of Patent: November 23, 2004
    Assignee: Baylor College of Medicine
    Inventors: Frank M. Orson, Berma M. Kinsey, Balbir S. Bhogal
  • Macroaggregated protein conjugates as oral genetic immunization delivery agents
    Publication number: 20030165476
    Abstract: This invention relates to the development of an expression vector containing an antigenic genomic sequence, which is bound to an aggregated protein-polycationic polymer conjugate. More particularly it relates to the use of the expression vector as an oral DNA vaccine or to induce immune response. In specific embodiments, the expression vector is bound to a protein-polycationic polymer suspension.
    Type: Application
    Filed: April 6, 2001
    Publication date: September 4, 2003
    Inventors: Frank M. Orson, Berma M. Kinsey, Balbir S. Bhogal
  • Stabilization of lipid:DNA formulations during nebulization
    Patent number: 6375980
    Abstract: The present invention provides a liposomal aerosol composition, comprising a pharmaceutical compound, a cationic lipid, a neutral co-lipid; and tryptone. Also provided is a nebulized cationic lipid: neutral co-lipid: DNA suspension useful for lipid-DNA transfections, wherein the cationic lipid is bis(guanidinium)-tren-cholesterol and the neutral co-lipid is dioleoylphosphatidylethanolamine (DOPE).
    Type: Grant
    Filed: July 19, 1999
    Date of Patent: April 23, 2002
    Assignee: Research Development Foundation
    Inventors: Charles L. Densmore, Jr., J. Vernon Knight, J. Clifford Waldrep, Berma M. Kinsey
  • Stabilization of lipid:DNA formulations during nebulization
    Patent number: 6106859
    Abstract: The present invention provides a liposomal aerosol composition, comprising a pharmaceutical compound, a cationic lipid, (c) a neutral co-lipid; and (d) tryptone. Also provided is a nebulized cationic lipid:DNA suspension useful for lipid-DNA transfections, wherein said cationic lipid is bis(guanidinium)-tren-cholesterol.
    Type: Grant
    Filed: January 8, 1999
    Date of Patent: August 22, 2000
    Inventors: Charles L. Densmore, Jr., J. Vernon Knight, J. Clifford Waldrep, Berma M. Kinsey