Patents by Inventor Bernard Antoni Zonnenberg

Bernard Antoni Zonnenberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9731037
    Abstract: The invention provides a scanning suspension comprising a particle which is capable of at least in part disturbing a magnetic field, wherein said particle comprises a diameter of at least 1 ?m, and use thereof for obtaining a scanning image. Preferably, said particle comprises holmium and a composition capable of essentially maintaining its structure during irradiation. A particle of the invention is suitable for preparing a kit of parts, comprising a diagnostic and a therapeutic composition which both comprise particles of the invention with essentially the same chemical structure, wherein said therapeutic composition is more radioactive than said diagnostic composition. Said kit of parts is especially suitable for treatment of a tumor. First, the distribution of a particle of the invention within an individual can be determined with a scanning image obtained with said scanning composition.
    Type: Grant
    Filed: December 17, 2013
    Date of Patent: August 15, 2017
    Assignees: Universitair Medisch Centrum Utrecht, Universiteit Utrecht Holding B.V.
    Inventors: Johannes Franciscus Wilhelmus Nijsen, Alfred Dirk Van Het Schip, Bernard Antoni Zonnenberg
  • Publication number: 20140227177
    Abstract: The invention provides a scanning suspension comprising a particle which is capable of at least in part disturbing a magnetic field, wherein said particle comprises a diameter of at least 1 ?m, and use thereof for obtaining a scanning image. Preferably, said particle comprises holmium and a composition capable of essentially maintaining its structure during irradiation. A particle of the invention is suitable for preparing a kit of parts, comprising a diagnostic and a therapeutic composition which both comprise particles of the invention with essentially the same chemical structure, wherein said therapeutic composition is more radioactive than said diagnostic composition. Said kit of parts is especially suitable for treatment of a tumor. First, the distribution of a particle of the invention within an individual can be determined with a scanning image obtained with said scanning composition.
    Type: Application
    Filed: December 17, 2013
    Publication date: August 14, 2014
    Applicants: Universiteit Utrecht Holding B.V., Universitair Medisch Centrum Utrecht
    Inventors: Johannes Franciscus Wilhelmus NIJSEN, Alfred Dirk VAN HET SCHIP, Bernard Antoni ZONNENBERG
  • Patent number: 8632751
    Abstract: The invention provides a scanning suspension comprising a particle which is capable of at least in part disturbing a magnetic field, wherein said particle comprises a diameter of at least 1 ?m, and use thereof for obtaining a scanning image. Preferably, said particle comprises holmium and a composition capable of essentially maintaining its structure during irradiation. A particle of the invention is suitable for preparing a kit of parts, comprising a diagnostic and a therapeutic composition which both comprise particles of the invention with essentially the same chemical structure, wherein said therapeutic composition is more radioactive than said diagnostic composition. Said kit of parts is especially suitable for treatment of a tumor. First, the distribution of a particle of the invention within an individual can be determined with a scanning image obtained with said scanning composition.
    Type: Grant
    Filed: December 29, 2004
    Date of Patent: January 21, 2014
    Assignees: Universitair Medisch Centrum Utrecht, Universiteit Utrecht Holding B.V.
    Inventors: Johannes Franciscus W. Nijsen, Alfred Dirk van het Schip, Bernard Antoni Zonnenberg
  • Patent number: 6373068
    Abstract: An irradiation vessel is made from such material and in such form that it can also be used as administration vessel of a medicine contained therein, this medicine first being irradiated with neutrons in a nuclear reactor and subsequently being administered as radioactive medicine to a patient without the medicine having to be moved outside the vessel intermediately. To prevent additional handling operations, with the risk of contamination of the medicine, higher radiation doses to personnel and radioactive contamination of the environment when vessels are used in which the irradiation and administration take place separately, a vessel has been developed which allows a medicine to be irradiated and to be directly administered to the patient thereafter via an external carrier liquid.
    Type: Grant
    Filed: November 24, 1999
    Date of Patent: April 16, 2002
    Assignee: Academisch Ziekenhuis Utrecht
    Inventors: Johannes Franciscus Wilhelmus Nijsen, Alfred Dirk van het Schip, Bernard Antoni Zonnenberg