Patents by Inventor Bernard Baudoin

Bernard Baudoin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1-oxo-isoindoline-4-carboxamide and 1-oxo-1,2,3,4-tetrahydroisoquinoline-5-carboxamide derivatives, preparation and therapeutic use thereof
    Patent number: 8372864
    Abstract: The present invention relates to derivatives of 1-oxo-isoindoline-4-carboxamides and of 1-oxo-1,2,3,4-tetrahydroisoquinoline-5-carboxamides, to the preparation thereof and to the therapeutic use thereof.
    Type: Grant
    Filed: January 26, 2010
    Date of Patent: February 12, 2013
    Assignee: Sanofi
    Inventors: Bernard Baudoin, Michel Evers, Arielle Genevois-Borella, Andreas Karlsson, Jean-Luc Malleron, Magali Mathieu
  • 1-OXO-ISOINDOLINE-4-CARBOXAMIDE AND 1-OXO-1,2,3,4-TETRAHYDROISOQUINOLINE-5-CARBOXAMIDE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF
    Publication number: 20100197725
    Abstract: The present invention relates to derivatives of 1-oxo-isoindoline-4-carboxamides and of 1-oxo-1,2,3,4-tetrahydroisoquinoline-5-carboxamides, to the preparation thereof and to the therapeutic use thereof.
    Type: Application
    Filed: January 26, 2010
    Publication date: August 5, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Bernard BAUDOIN, Michel EVERS, Arielle GENEVOIS-BORELLA, Andreas KARLSSON, Jean-Luc MALLERON, Magali MATHIEU
  • 1,2,3,4-TETRAHYDROPYRROLO[1,2-A]PYRAZINE-6-CARBOXAMIDE AND 2,3,4,5-TETRAHYDROPYRROLO[1,2-a][1,4]-DIAZEPINE-7-CARBOXAMIDE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF
    Publication number: 20100197668
    Abstract: The present invention relates to derivatives of 1,2,3,4-tetrahydropyrrolo-[1,2-a]pyrazine-6-carboxamides and of 2,3,4,5-tetrahydropyrrolo[1,2-a][1,4]diazepine-7-carboxamides, to the preparation thereof and to the therapeutic use thereof.
    Type: Application
    Filed: January 26, 2010
    Publication date: August 5, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Bernard BAUDOIN, Michel EVERS, Arielle GENEVOIS-BORELLA, Andreas KARLSSON, Jean-Luc MALLERON, Magali MATHIEU
  • Pyridazinone derivatives as pharmaceuticals and pharmaceutical compositions containing them
    Patent number: 7462613
    Abstract: The present invention relates to novel pyridazinone derivatives of the general formula (I) wherein A is A1 or A2; R is unsubstituted or at least monosubstituted C1-C10-alkyl, aryl, aryl-(C1-C10-alkyl)-, heteroaryl, heteroaryl-(C1-C10-alkyl)-, heterocyclyl, heterocyclyl-(C1-C10-alkyl)-, C3-C10-cycloalkyl, polycycloalkyl, C2-C10-alkenyl or C2-C10-alkinyl and Ar is unsubstituted or at least monosubstituted aryl or heteroaryl.
    Type: Grant
    Filed: November 19, 2003
    Date of Patent: December 9, 2008
    Assignee: SANOFI-AVENTIS Deutschland GmbH
    Inventors: Swen Hölder, Thorsten Naumann, Karl Schönafinger, David William Will, Hans Matter, Günther Müller, Dominique Le Suisse, Bernard Baudoin, Thomas Rooney, Franck Halley, Gilles Tiraboschi, Cécile Combeau, Ingrid Sassoon, Anke Steinmetz
  • Substituted tetrahydro-1-pyrazolo [3,4-]pyridines compositions comprising them, and use
    Patent number: 7435820
    Abstract: Substituted tetrahydro-1H-pyrazolo[3,4-c]pyridines, compositions comprising them and use. The present invention relates in particular to novel substituted tetrahydro-1H-pyrazolo[3,4-c]pyridines having therapeutic activity, which can be used in particular in oncology.
    Type: Grant
    Filed: May 23, 2006
    Date of Patent: October 14, 2008
    Assignee: Aventis Pharma S.A.
    Inventors: Fabienne Thompson, Catherine Souaille, Fabrice Viviani, Michel Tabart, Patrick Mailliet, Teresa Damiano, Marie-Pierre Cherrier, Francois Clerc, Frank Halley, Herve Bouchard, Laurence Gauzy-Lazo, Bernard Baudoin
  • Pyridazinone derivatives as pharmaceuticals and pharmaceutical compositions containing them
    Patent number: 7309701
    Abstract: The present invention relates to novel pyridazinone derivatives of the general formula (I) wherein A is A1 or A2; R is unsubstituted or at least monosubstituted C1-C10-alkyl, aryl, aryl-(C1-C10-alkyl)-, heteroaryl, heteroaryl-(C1-C10-alkyl)-, heterocyclyl, heterocyclyl-(C1-C10-alkyl)-, C3-C10-cycloalkyl, polycycloalkyl, C2-C10-alkenyl or C2-C10-alkinyl and Ar is unsubstituted or at least monosubstituted aryl or heteroaryl.
    Type: Grant
    Filed: November 19, 2003
    Date of Patent: December 18, 2007
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Swen Hölder, Thorsten Naumann, Karl Schönafinger, David William Will, Hans Matter, Günther Müller, Dominique Le Suisse, Bernard Baudoin, Thomas Rooney, Franck Halley, Gilles Tiraboschi
  • Pyrrolopyrimidines
    Patent number: 7259154
    Abstract: Compounds of the formula and N-oxides, prodrugs, acid bioisosteres, pharmaceutically acceptable salts or solvates of such compounds, or N-oxides, prodrugs, or acid bioisosteres of such salts or solvates, to compositions comprising such compounds, and methods of treatment comprising administering, to a patient in need thereof, such compounds and compositions.
    Type: Grant
    Filed: December 23, 2003
    Date of Patent: August 21, 2007
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: Paul Joseph Cox, Tahir Nadeem Majid, Stephanie Daniele Deprets, Shelley Amendola, Iain McFarlane McLay, Christopher Edlin, David John Aldous, Brian Pedgrift, Frank Halley, Michael Edwards, Bernard Baudoin
  • Substituted tetrahydro-1H-pyrazolo [3,4-c] pyridines, compositions comprising them, and use
    Patent number: 7109340
    Abstract: Substituted tetrahydro-1H-pyrazolo[3,4-c]pyridines, compositions comprising them and use. The present invention relates in particular to novel substituted tetrahydro-1H-pyrazolo[3,4-c]pyridines having therapeutic activity, which can be used in particular in oncology.
    Type: Grant
    Filed: July 9, 2004
    Date of Patent: September 19, 2006
    Assignee: Aventis Pharma S.A.
    Inventors: Fabienne Thompson, Patrick Mailliet, Teresa Damiano, Marie-Pierre Cherrier, Francois Clerc, Frank Halley, Hervé Bouchard, Laurence Gauzy-Lazo, Bernard Baudoin, Catherine Souaille, Fabrice Viviani, Michel Tabart
  • SUBSTITUTED TETRAHYDRO-1H-PYRAZOLO [3,4-C]PYRIDINES COMPOSITIONS COMPRISING THEM, AND USE
    Publication number: 20060199837
    Abstract: Substituted tetrahydro-1H-pyrazolo[3,4-c]pyridines, compositions comprising them and use. The present invention relates in particular to novel substituted tetrahydro-1H-pyrazolo[3,4-c]pyridines having therapeutic activity, which can be used in particular in oncology.
    Type: Application
    Filed: May 23, 2006
    Publication date: September 7, 2006
    Applicant: AVENTIS PHARMA S.A.
    Inventors: Fabienne Thompson, Patrick Mailliet, Teresa Damiano, Marie-Pierre Cherrier, Francois Clerc, Frank Halley, Herve Bouchard, Laurence Gauzy-Lazo, Bernard Baudoin, Catherine Squaille, Fabrice Viviani, Michel Tabart
  • Substituted tetrahydro-1H-pyrazolo [3,4-c] pyridines, compositions comprising them, and use
    Publication number: 20050096345
    Abstract: Substituted tetrahydro-1H-pyrazolo[3,4-c]pyridines, compositions comprising them and use. The present invention relates in particular to novel substituted tetrahydro-1H-pyrazolo[3,4-c]pyridines having therapeutic activity, which can be used in particular in oncology.
    Type: Application
    Filed: July 9, 2004
    Publication date: May 5, 2005
    Applicant: Aventis Pharma S.A.
    Inventors: Fabienne Thompson, Patrick Mailliet, Teresa Damiano, Marie-Pierre Cherrier, Francois Clerc, Frank Halley, Herve Bouchard, Laurence Gauzy-Lazo, Bernard Baudoin, Catherine Souaille, Fabrice Viviani, Michel Tabart
  • Novel pyridazinone derivatives as pharmaceuticals and pharmaceutical compositions containing them
    Publication number: 20050026918
    Abstract: The present invention relates to novel pyridazinone derivatives of the general formula (I) wherein A is A1 or A2; R is unsubstituted or at least monosubstituted C1-C10-alkyl, aryl, aryl-(C1-C10-alkyl)-, heteroaryl, heteroaryl-(C1-C10-alkyl)-, heterocyclyl, heterocyclyl-(C1-C10-alkyl)-, C3-C10-cycloalkyl, polycycloalkyl, C2-C10-alkenyl or C2-C10-alkinyl and Ar is unsubstituted or at least monosubstituted aryl or heteroaryl.
    Type: Application
    Filed: November 19, 2003
    Publication date: February 3, 2005
    Inventors: Swen Holder, Thorsten Naumann, Karl Schonafinger, David Will, Hans Matter, Gunther Muller, Dominique Le Suisse, Bernard Baudoin, Thomas Rooney, Franck Halley, Gilles Tiraboschi, Cecile Combeau, Ingrid Sassoon, Anke Steinmetz
  • Novel pyridazinone derivatives as pharmaceuticals and pharmaceutical compositions containing them
    Publication number: 20040176377
    Abstract: The present invention relates to novel pyridazinone derivatives of the general formula (I) 1
    Type: Application
    Filed: November 19, 2003
    Publication date: September 9, 2004
    Inventors: Swen Holder, Thorsten Naumann, Karl Schonafinger, David William Will, Hans Matter, Gunther Muller, Dominique Le Suisse, Bernard Baudoin, Thomas Rooney, Franck Halley, Gilles Tiraboschi
  • Pyrrolopyrimidines
    Publication number: 20040142947
    Abstract: Compounds of the formula 1
    Type: Application
    Filed: December 23, 2003
    Publication date: July 22, 2004
    Applicant: Aventis Pharmaceuticals, Inc.
    Inventors: Paul Joseph Cox, Tahir Nadeem Majid, Stephanie Daniele Deprets, Shelley Amendola, Iain McFarlane McLay, Christopher Edlin, David John Aldous, Brian Pedgrift, Frank Halley, Michael Edwards, Bernard Baudoin
  • Farnesyl transferase inhibitors, preparation thereof and pharmaceuticals compositions containing said inhibitors
    Patent number: 5889053
    Abstract: Novel farnesyl transferase inhibitors of general formula (I), ##STR1## the preparation thereof and pharmaceutical compositions containing said inhibitors, are disclosed. In general formula (I), R.sub.1 is Y--S--A.sub.1 (where Y is a hydrogen atom, an amino acid residue, a fatty acid residue, an alkyl or alkoxycarbonyl radical or a radical R.sub.4 --S-- where R.sub.4 is a C.sub.1-4 alkyl radical optionally substituted by a phenyl radical or a radical of general formula (II) ##STR2## wherein A.sub.1, X, X.sub.1, Y.sub.1, R'.sub.1, R.sub.2, R'.sub.2 and R are defined as below, and A.sub.1 is a C.sub.1-4 alkylene radical optionally alpha-substituted in the >C(X.sub.1)(Y.sub.1) grouping by an amino or alkylamino, dialkylamino, alkanoylamino or alkoxycarbonylamino radical); X.sub.1 and Y.sub.1 are each a hydrogen atom or, taken together with the carbon atom to which they are attached, form a >C.dbd.O grouping; R'.sub.1 is hydrogen or a C.sub.1-6 alkyl radical; X is an oxygen or sulphur atom; R.sub.2 is a C.
    Type: Grant
    Filed: January 9, 1998
    Date of Patent: March 30, 1999
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Bernard Baudoin, Christopher Burns, Alain Commercon, Alain Lebrun
  • Farnesyl transferase inhibitors, their preparation and the pharmaceutical compositions which contain them
    Patent number: 5861529
    Abstract: This invention relates to transferase inhibitors of the formula (I), their preparation, and pharmaceutical compositions containing them. ##STR1## In formula (I), R.sub.1 is Y--S--A.sub.1 --(Y is a hydrogen atom, an amino acid residue, a fatty acid residue, an alkyl radical, an alkoxycarbonyl radical, or an R.sub.4 --S-- radical in which R.sub.4 is an alkyl radical containing 1 to 4 carbon atoms optionally substituted by a phenyl radical or a radical of the formula (II) ##STR2## in which A.sub.1 is an alkylene radical containing 1 to 4 carbon atoms optionally substituted at the position a in the grouping >C(X.sub.1)(Y.sub.1) with an amino, alkylamino, dialkylamino, alkanoylamino, or alkoxycarbonylamino radical); X.sub.1 and Y.sub.1 are each a hydrogen atom or form, together with the carbon atom to which they are connected, a >C.dbd.O grouping; R'.sub.1 is hydrogen or methyl; R.sub.
    Type: Grant
    Filed: June 18, 1997
    Date of Patent: January 19, 1999
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Bernard Baudoin, Christopher Burns, Alain Commercon, Jean-Dominique Guitton
  • Farnesyl transferase inhibitors, preparation thereof and pharmaceutical compositions containing same
    Patent number: 5750567
    Abstract: Novel farnesyl transferase inhibitors of general formula (I) ##STR1## preparation thereof and pharmaceutical compositions containing same. In general formula (I), R.sub.1 is Y--S--A.sub.1 -- (where Y is a hydrogen atom, an amino acid residue, a fatty acid residue, or an alkyl or alkoxycarbonyl radical, and A.sub.1 is a C.sub.1-4 alkylene radical optionally .alpha.-substituted in the >C(X.sub.1) (Y.sub.1,) grouping by an amino, alkylamino, alkanoylamino or alkoxycarbonylamino radical wherein the alkyl or alkanoyl portion contains 1-6 carbon atoms; each of X.sub.1 and Y.sub.1 is a hydrogen atom or X.sub.1 and Y.sub.1, taken toether with the carbon atom to which they are attached, form a >C.dbd.O grouping; R'.sub.1 is hydrogen or a C.sub.1-6 alkyl radical; X is an oxygen or sulphur atom; R.sub.2 is a C.sub.1-6 alkyl, alkenyl or alkynyl radical optionally substituted by hydroxy, alkoxy, mercapto, alkylthio, alkylsulphinyl or alkylsulphonyl.
    Type: Grant
    Filed: July 15, 1997
    Date of Patent: May 12, 1998
    Assignee: Phone-Poulenc Rorer SA.
    Inventors: Bernard Baudoin, Christopher Burns, Alain Commercon, Alain Le Brun