Abstract: The present invention relates to a method of preparation of a solid substrate capable of immobilizing at least one cell and/or at least one part of a cell, said method comprising a step consisting of fixing, to said solid substrate, a fusogenic compound capable of being inserted in cell membranes. The present invention also relates to a method for immobilizing at least one cell and/or at least one part of a cell using the solid substrate thus prepared, said solid substrate and its uses in the area of biomedical diagnostics or health monitoring of biological fluids or intended for human or animal use.

Abstract: The invention concerns a microfluidic device and its uses for capturing subset of cells in a biological fluid. Said device comprises a chamber (1) for circulating fluids whereof an inner wall (5) is provided with a covalent immobilization surface in the form of an organized self-assembled silane layer, whereto is fixed a layer of biomolecules for specific identification of the population of cells.

Abstract: A novel process for the synthesis of ortho-substituted benzoic acid by lithiating an unprotected benzoic acid and a number of novel orth-substituted benzoic acids are described.