Abstract: An antiparasitic combination therapy compising a combination of a 13-monosaccharide 5-oxime avermectin, such as selamectin, and praziquantel in a veterinarily acceptable carrier, diluent or adjuvant. Also provided is a method of treatment or prophylaxis of a parasitic infestation as well as a kit useful in the treatment or prophylaxis of a parasitic infestation of flea, heartworm or tapeworm in a mammal.

Abstract: A means to engage two vertical pipes or tubes of unlike and increasing size that have been co-inserted such as with a roof or floor drain, in a manner that prevents the contained fluid from overspilling when the said pipes become full or when the fluid flows in a direction opposite from normal gravity flow, which is generally considered as flow from the smaller to the larger pipe. The means of engagement closes the void between the inside diameter larger pipe and outside diameter smaller pipe to withstand fluid pressure in a way that accounts for angular misalignment, pipe or tube eccentricity, manufacturing tolerance, as well as tube condition and debris attached to either pipe sidewall. More specifically, a roof drain system for existing roofs or new construction including a flanged outlet pipe for insertion into the roof drain pipe with the flange mounted on top of the roof. A water straining system is mounted on top of the flange.

Abstract: A means to engage two vertical pipes or tubes of unlike and increasing size that have been co-inserted such as with a roof or floor drain, in a manner that prevents the contained fluid from overspilling when the said pipes become full or when the fluid flows in a direction opposite from normal gravity flow, which is generally considered as flow from the smaller to the larger pipe. The means of engagement closes the void between the inside diameter larger pipe and outside diameter smaller pipe to withstand fluid pressure in a way that accounts for angular misalignment, pipe or tube eccentricity, manufacturing tolerance, as well as tube condition and debris attached to either pipe sidewall. More specifically, a roof drain system for existing roofs or new construction including a flanged outlet pipe for insertion into the roof drain pipe with the flange mounted on top of the roof. A water straining system is mounted on top of the flange.