Patents by Inventor Bernard Franklin Gupton

Bernard Franklin Gupton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for making 5,11-Dihydro-11-ethyl-5-methyl-8{2-{(1-oxido-4-quinolinyl)oxy}ethyl}-6H-di pyrido[3,2-b:2?,3?-e][1,4]diazepin-6-one
    Patent number: 7282583
    Abstract: An improved process for making 5,11-dihydro-11-ethyl-5-methyl-8-{2-{(1-oxido-4-quinolinyl)oxy}ethyl}-6H-di pyrido[3,2-b:2?,3?-e][1,4]diazepin-6-one.
    Type: Grant
    Filed: November 16, 2006
    Date of Patent: October 16, 2007
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Saeed Ahmad, Robert Frederick Boswell, Jr., Jack Delbert Brown, Cary Mark Davis, Kai Oliver Donsbach, Bernard Franklin Gupton, Christopher Peter Johnson, III, Ahmad Khodabocus, Vithalanand R. Kulkarni, Young S. Lo
  • Method for making nevirapine
    Patent number: 6680383
    Abstract: A process for making nevirapine, comprising the following steps: (a) reacting a 2-halo-3-pyridinecarbonitrile of the formula wherein X is a fluorine, chlorine, bromine or iodine atom, preferably chlorine or bromine, with cyclopropylamine, to yield 2-(cyclopropylamino)-3-pyridinecarbonitrile; (b) hydrolyzing the 2-(cyclopropylamino)-3-pyridinecarbonitrile to yield 2-(cyclopropylamino)-3-pyridine carboxylic acid; (c) isolating the 2-(cyclopropylamino)-3-pyridine carboxylic acid from the reaction medium; (e) treating the 2-(cyclopropylamino)-3-pyridine carboxylic acid with a chlorinating agent, to yield 2-(cyclopropylamino)-3-pyridinecarbonyl chloride; (f) reacting the 2-(cyclopropylamino)-3-pyridine carbonyl chloride with a 2-halo-4-methyl-3-pyridinamine of the formula wherein X is a fluorine, chlorine, bromine or iodine atom, preferably chlorine or bromine, to produce an N-(2-halo-4-methyl-3-pyridinyl)-2-(cyclopropylamino)-3-pyridinecarboxamide; and (g) cyclizing the N-
    Type: Grant
    Filed: June 5, 2003
    Date of Patent: January 20, 2004
    Assignee: Boehringer Ingelheim Chemicals, Inc.
    Inventors: Robert Frederick Boswell, Bernard Franklin Gupton, Young Sek Lo
  • Method for making nevirapine
    Publication number: 20040002603
    Abstract: A process for making nevirapine, comprising the following steps:
    Type: Application
    Filed: June 5, 2003
    Publication date: January 1, 2004
    Applicant: Boehringer ingelheim Chemicals, Inc.
    Inventors: Robert Frederick Boswell, Bernard Franklin Gupton, Young Sek Lo
  • Process for making 3-amino-2-chloro-4-methylpyridine
    Patent number: 6399781
    Abstract: A method for making 3-amino-2-chloro-4-methylpyridine, as shown in Scheme 12, below.
    Type: Grant
    Filed: September 12, 2001
    Date of Patent: June 4, 2002
    Assignee: Boehringer Ingelheim Chemicals, Inc.
    Inventor: Bernard Franklin Gupton
  • Process for making 3-amino-2-chloro-4-methylpyridine
    Publication number: 20020052507
    Abstract: A method for making 3-amino-2-chloro-4-methylpyridine, as shown in Scheme 12, below.
    Type: Application
    Filed: September 12, 2001
    Publication date: May 2, 2002
    Inventor: Bernard Franklin Gupton