Abstract: A system for the application of knots in surgical suture material consists of a pre-knotted surgical suture means (1) and a surgical knot applicator. The pre-knotted surgical suture means (1) has a sleeve (10) open at both ends (12, 13) and a surgical suture material (15) such as thread, cord, etc., which suture material is tied around the sleeve (10) to produce a pre-knotted displaceable knot (18) and has a free end (16). The surgical knot applicator contains a shaft, whose distal end-zone comprises an opening corresponding to the diameter of the sleeve (10). The sleeve (10) inserted with its proximal zone (12) into this opening is pulled back into the interior space of the shaft with a pulling-in device. The suture and the knot (18) are pulled tight by moving the free end (16) of the surgical suture material (15) guided through the sleeve (10) in proximal direction (arrow) with a pulling device.