Patents by Inventor Bernard Hublot

Bernard Hublot has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical composition for the prevention or treatment of cerebral oedemas
    Publication number: 20070021415
    Abstract: The present invention relates to the use of at least one compound of formula (I) below: or of its pharmaceutically acceptable salts, in the preparation of a medicament for the prevention or treatment of cerebral oedemas.
    Type: Application
    Filed: July 18, 2006
    Publication date: January 25, 2007
    Inventors: Marie-Emmanuelle Le Guern, Philippe Girard, Jean-Marie Gillardin, Laurence Berthon-Cedille, Bernard Hublot
  • Pharmaceutical composition intended for the prevention or for the treatment of cerebral oedemas
    Publication number: 20060276472
    Abstract: The present invention relates to the use of at least one compound of formula (I) below: or at least one of the pharmaceutically acceptable salts thereof, for the preparation of a medicament intended for the prevention or for the treatment of cerebral oedemas.
    Type: Application
    Filed: June 5, 2006
    Publication date: December 7, 2006
    Inventors: Marie-Emmanuelle Le Guern, Philippe Girard, Jean-Marie Gillardin, Laurence Berthon-Cedille, Bernard Hublot
  • Method of treating intestinal disorders with citrulline
    Publication number: 20060247315
    Abstract: The present invention relates to the use of L-citrulline (I) for the preparation of a medicament intended for the treatment of pathologies linked to an intestinal insufficiency.
    Type: Application
    Filed: June 30, 2006
    Publication date: November 2, 2006
    Applicants: BIOCODEX, UNIVERSITE RENE DESCARTES PARIS 5
    Inventors: Sylwia Osowska-Vincent, Christophe Moinard, Luc Cynober, Marie-Emmanuelle Le Guern, Bernard Hublot, Paul Bernasconi
  • Use of pharmacological compounds for the prevention or treatment of acute tolerance to morphines
    Publication number: 20060160789
    Abstract: The present invention relates to the use of at least one compound of the following general formula (I): or its pharmaceutically acceptable salts, for the preparation of a medicament intended for the prevention or treatment of acute tolerance to morphines or hyperalgesia caused by morphines, in an individual having received an administration of a morphine analgesic.
    Type: Application
    Filed: December 30, 2005
    Publication date: July 20, 2006
    Inventors: Myriam Tirault, Bertrand Debaene, Marie-Emmanuelle Le Guern, Bernard Hublot
  • Method for treating weight loss in patients suffering from inflammatory bowel diseases
    Publication number: 20060140973
    Abstract: The present invention relates to a method of treating or preventing weight loss of patients with inflammatory bowel diseases comprising administering to said patients an effective amount of Saccharomyces boulardii.
    Type: Application
    Filed: December 23, 2004
    Publication date: June 29, 2006
    Inventors: Bernard Hublot, Herve Groux, Rene Levy, Marie-Emmanuelle Le Guern, Paul Bernasconi
  • Use of citrulline within the framework of intestinal insufficiency
    Publication number: 20050239891
    Abstract: The present invention relates to the use of L-citrulline (I) for the preparation of a medicament intended for the treatment of pathologies linked to an intestinal insufficiency.
    Type: Application
    Filed: July 8, 2004
    Publication date: October 27, 2005
    Inventors: Sylwia Osowska-Vincent, Christophe Moinard, Luc Cynober, Marie-Emmanuelle Le Guern, Bernard Hublot, Paul Bernasconi
  • Process for reducing the extent of cryptosporidium diarrhoeas
    Patent number: 5665352
    Abstract: Process for reducing the extent of Cryptosporidium diarrhoeas, which comprises administering to a patient in need thereof a therapeutically effective amount of yeasts of the Saccharomyces boulardii species. The yeasts are freeze-dried living yeasts. The yeasts are provided in the form of unit doses containing 0.050 to 3.0 g of yeasts.
    Type: Grant
    Filed: October 12, 1994
    Date of Patent: September 9, 1997
    Assignee: Laboratoires Biocodex
    Inventors: Henri Blehaut, Bernard Hublot
  • N(pyrazol-3-yl) benzamides and pharmaceutical compositions
    Patent number: 5464860
    Abstract: The invention relates to a compound useful for treating epilepsy selected from the compounds of the general formula: ##STR1## in which R.sub.1 is C.sub.1 -C.sub.4 alkyl,R.sub.2 is C.sub.1 -C.sub.4 alkyl,R.sub.3 is selected from hydrogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy and C.sub.1 -C.sub.4 hydroxyalkyl, andR.sub.4 is selected from hydrogen, C.sub.1 -C.sub.4 alkyl, C.sub.2 -C.sub.7 alkanoyl and C.sub.1 -C.sub.4 hydroxyalkyl.
    Type: Grant
    Filed: June 16, 1993
    Date of Patent: November 7, 1995
    Assignee: Novapharme
    Inventors: Francis Lepage, Bernard Hublot
  • 3-Isoxazoyl derivatives endowed with anticonvulsant activity, procedure for their preparation and their pharmaceutical compositions
    Patent number: 5258397
    Abstract: The object of the invention is heterocyclic compounds of general formula (I) endowed with anticonvulsant activity: ##STR1## in which Y is selected from --O--, --S-- and ##STR2## R.sub.4 being H or optionally substituted alkyl, acyl or benzyl, Z is selected from the groups --CO--N(R.sub.6)--,--NH--CO--CH.dbd.CH-- and --N(R.sub.6)--CO, R.sub.6 being H or alkyl;R.sub.1 is C.sub.1 -C.sub.4 alkyl; R.sub.2 is C.sub.1 -C.sub.4 alkyl or halogen; R.sub.3 represents optionally substituted C.sub.1 -C.sub.4 alkyl, alkoxy or hydroxyalkyl, or C.sub.2 -C.sub.7 alkanoyl.
    Type: Grant
    Filed: May 9, 1991
    Date of Patent: November 2, 1993
    Assignee: Novapharme
    Inventors: Francis Lepage, Bernard Hublot
  • Novel isoxazole and isoxazoline compounds with anticonvulsant activity process for their preparation and therapeutic composition containing them
    Patent number: 5059614
    Abstract: The object of the invention are anticonvulsant heterocyclic compounds of general formula: ##STR1## in which R.sub.1 and R.sub.2 is each selected from C.sub.1 -C.sub.4 alkyl, phenyl, benzyl, trifluoromethyl or halogen, R.sub.3 is selected from hydrogen, hydroxy, C.sub.1 -C.sub.4 alkyl or alkoxy, R.sub.4, in position 3 or 5, is selected from hydrogen, trifluoromethyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkyl, or C.sub.1 -C.sub.4 hydroxyalkyl,R.sub.5 is selected from hydrogen or C.sub.4 -C.sub.4 alkyl or R.sub.4 and R.sub.5 together form a tetramethylene group, Z at position 3 or 5 on the heterocycle is selected from:--N(R.sub.6)--CO--, --CO--N(R.sub.6)--, --N(R.sub.6)--CO--N(R.sub.6)----CH(R.sub.6)--NH--CO--, or --NH-CO--CH(R.sub.6),in which R.sub.6 is selected from hydrogen or C.sub.1 -C.sub.4 alkyl.
    Type: Grant
    Filed: November 29, 1989
    Date of Patent: October 22, 1991
    Assignee: Novapharme
    Inventors: Francis Lepage, Bernard Hublot
  • Antiulcer benzimidazoles
    Patent number: 4745125
    Abstract: Antiulcer amino-benzimidazole compounds substituted on the nitrogen; these compounds correspond to the following general formula: ##STR1## in which the various substituents are defined hereinbelow.
    Type: Grant
    Filed: January 20, 1987
    Date of Patent: May 17, 1988
    Assignee: Novapharme
    Inventors: Jacques N. Astoin, Bernard Hublot, Francis Lepage
  • Method for preventing or treating pseudo-membranous colitis
    Patent number: 4595590
    Abstract: The invention relates to a method for preventing or treating pseudo-membranous colitis in a patient submitted to antibiotic treatment by means of Saccharomyces yeasts.
    Type: Grant
    Filed: January 17, 1984
    Date of Patent: June 17, 1986
    Assignee: Laboratoires Biocodex
    Inventors: Bernard Hublot, Rene H. Levy