Patent number: 5464781
Abstract: This invention relates to compounds of formula I and pharmaceutically acceptable salts thereof ##STR1## in which R.sub.1 represents hydrogen, alkyl, hydroxy, carboxyalkenyl, alkoxycarbonyalkenyl, hydroxyalkyl, carboxyalkyl, alkoxycarbonylalkyl, alkoxy, halogenated alkyl, carboxy alkoxycarbonyl or alkanoylamino; R.sub.2 represents hydrogen, halo, alkoxy, hydroxy, alkanoyloxy, or phenoxy; R.sub.3 represents hydrogen or alkyl; R.sub.4 represents hydrogen, halo, alkoxycarbonyl, a benzyloxycarbonyl, alkanoyl, benzoyl, carbamoyl, alkyl, carboxy, hydroxyalkyl or alkylthio; R.sub.5 represents hydrogen or alkyl; R.sub.6 represents hydrogen, alkyl [optionally substituted by one or more of the following: hydroxy, halo or an amino group of formula --NR.sub.12 R.sub.13 ], a C.sub.3-12 alicyclic hydrocarbon group, phenyl, (cycloalkyl)alkyl or benzyl; R.sub.7 represents hydrogen, halo, trifluoromethyl, trifluoromethoxy, alkyl, carboxy, or alkoxy; R.sub.
Type:
Grant
Filed:
June 3, 1994
Date of Patent:
November 7, 1995
Assignee:
The Boots Company PLC
Inventors:
Bernard J. Armitage, John G. Bowen, Malcolm J. Crossley, Ian M. Hunneyball, Bruce W. Leslie, Thomas K. Miller, Michael Spowage