Patents by Inventor Bernard J. Ludwig

Bernard J. Ludwig has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for suppressing histamine release
    Patent number: 4124723
    Abstract: A method for suppressing the release of histamine from sensitized leukocytes in warm blooded animals which comprises administering internally to said animals compounds of the formula: ##STR1## wherein n is a whole integer from 1 to 4; X is halogen and Z is COOH, CH.sub.2 OR or ##STR2## R being a lower alkyl chain of from 1 to 6 carbon atoms and pharmaceutically acceptable salts of those compounds wherein Z is COOH, in sufficient amount to suppress the release of histamine from said cells.
    Type: Grant
    Filed: February 18, 1977
    Date of Patent: November 7, 1978
    Assignee: Carter-Wallace, Inc.
    Inventors: David B. Reisner, Bernard J. Ludwig, George M. Fukui, Frank M. Berger
  • 2,3,4,4A-Tetrahydro-10H-1,2-oxazino[3,2-b](1,3)benzoxazin-10-ones
    Patent number: 4024139
    Abstract: Chemical compounds of the formula: ##STR1## wherein X is hydrogen, hydroxy, halogen, lower alkyl, lower alkoxy, nitro, amino, acetamido, sulfonamido or trifluoromethyl, and each R is selected from the group consisting of hydrogen and lower alkyl. Said compounds have valuable anti-inflammatory activity in standard laboratory animals.
    Type: Grant
    Filed: May 8, 1972
    Date of Patent: May 17, 1977
    Assignee: Carter-Wallace, Inc.
    Inventors: David B. Reisner, Bernard J. Ludwig, Harold M. Bates, Frank M. Berger