Abstract: The invention relates to an apparatus (1) for removing and depositing micro-drops (2′) of solutions from/on a surface (2), in particular chemical or biological solutions. The inventive apparatus comprises at least one micropipette or deposit point (3) which is mounted on a head (4) that can move in at least one direction, at least between one or more removal sites (5) and one or more deposit sites (6). Said apparatus is characterised in that the micropipette(s) (3) are mounted in the body of said head (4) and they can be moved in translation in relation to said head, by means of a device for controlling and limiting the application force of the micropipette(s) (3) on the deposit surface (2). Said controlling and limiting device is connected to a device for guiding said micropipette(s) in translation in relation to the head (4), while they are in contact with said surface (2) or in order to bring them into contact with said surface (2).