Patents by Inventor Bernard Loev

Bernard Loev has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical compositions and methods of inhibiting gastric acid secretion
    Patent number: 3956494
    Abstract: Pharmaceutical compositions and methods of inhibiting gastric acid secretion by administering 2-alkoxy(and 2-amino)-3-amino-2-heterocyclic-2-thiopropanamides.
    Type: Grant
    Filed: May 8, 1975
    Date of Patent: May 11, 1976
    Assignee: SmithKline Corporation
    Inventor: Bernard Loev
  • 5-Heterocyclic-1,2,3,6-tetrahydro-4(5H) pyrimidinone
    Patent number: 3956325
    Abstract: The compounds of this invention are 5-heterocyclic-1,2,3,6-tetrahydro-4(5H)-pyrimidinethiones which have pharmacological activity, in particular gastric acid secretion inhibitory activity, and 5-heterocyclic-1,2,3,6-tetrahydro-4(5H)-pyrimidinones which are intermediates in the preparation therefor.
    Type: Grant
    Filed: June 6, 1975
    Date of Patent: May 11, 1976
    Assignee: SmithKline Corporation
    Inventor: Bernard Loev
  • 1,3,5-Tricarbo-1,4-dihydropyridines
    Patent number: 3956341
    Abstract: N-Substituted 1,4-dihydropyridines are prepared by reaction of the corresponding N-unsubstituted 1,4-dihydropyridines with an alkyl haloformate, an acid halide or a carbamyl halide in the presence of base. These compounds have hypotensive activity.
    Type: Grant
    Filed: February 21, 1974
    Date of Patent: May 11, 1976
    Assignee: SmithKline Corporation
    Inventor: Bernard Loev
  • Pharmaceutical compositions and methods of inhibiting gastric acid secretion
    Patent number: 3950522
    Abstract: Pharmaceutical compositions and methods of inhibiting gastric acid secretion by administering N-alkenyl and N-alkynyl thioamides.
    Type: Grant
    Filed: March 28, 1975
    Date of Patent: April 13, 1976
    Assignee: SmithKline Corporation
    Inventor: Bernard Loev
  • N-(Heterocycl ic-alkyl)-9-xanthenylamines
    Patent number: 3949076
    Abstract: The compounds are N-(imidazolylalkyl, imidazolinylalkyl and tetrahydropyrimidylalkyl)-9-xanthenylamines which have gastric acid secretion inhibitory activity.
    Type: Grant
    Filed: May 29, 1975
    Date of Patent: April 6, 1976
    Assignee: SmithKline Corporation
    Inventors: Paul E. Bender, Bernard Loev, Perchonock, Carl D.
  • 2-Alkoxy(and 2-amino)-3-amino-2-heterocyclic-thiopropanamides
    Patent number: 3948892
    Abstract: The compounds are 2-alkoxy(and 2-amino)-3-amino-2-heterocyclic-thiopropanamides, for example 2-methoxy-N-methyl-3-morpholino-2-(2-pyridyl)thiopropanamide, which are inhibitors of gastric acid secretion.
    Type: Grant
    Filed: October 15, 1974
    Date of Patent: April 6, 1976
    Assignee: SmithKline Corporation
    Inventor: Bernard Loev
  • N-aminomethyl-2-amino(and 2-amino-methyl)-2-(2-quinolyl)-thioacetamides
    Patent number: 3933811
    Abstract: The compounds are N-aminomethyl-2-amino(and 2-aminomethyl)-2-heterocyclic-thioacetamides which are inhibitors of gastric acid secretion.
    Type: Grant
    Filed: September 18, 1974
    Date of Patent: January 20, 1976
    Assignee: SmithKline Corporation
    Inventors: L. Martin Brenner, Bernard Loev
  • Pharmaceutical compositions and methods of inhibiting gastric acid secretion
    Patent number: 3932641
    Abstract: Pharmaceutical compositions and methods of inhibiting gastric acid secretion by administering N-aminomethyl heterocyclic thioacetamide compounds.
    Type: Grant
    Filed: December 3, 1974
    Date of Patent: January 13, 1976
    Assignee: SmithKline Corporation
    Inventors: Henry C. Caldwell, Bernard Loev
  • 3-Alkyl xanthene compounds
    Patent number: 3931232
    Abstract: The compounds of this invention are 3-alkyl xanthenes having pharmacological activity such as central nervous system activity. Preferred compounds of this invention are 3-(1,2-dimethylheptyl)-5,6,7,8-tetrahydro-1-hydroxy-9-methylxanthene, 3-(1,2-dimethylheptyl)-1-hydroxy-6,9-dimethylxanthene and 3-(1,2-dimethylheptyl)-1-hydroxy-9-methylxanthene.
    Type: Grant
    Filed: June 24, 1974
    Date of Patent: January 6, 1976
    Assignee: SmithKline Corporation
    Inventors: Paul E. Bender, Bernard Loev
  • N-Aminomethyl heterocyclic thioacetamides
    Patent number: 3931162
    Abstract: N-Aminomethyl heterocyclic thioacetamide compounds are prepared by reacting a heterocyclic thioacetamide with formaldehyde and an amine. The products inhibit gastric acid secretion.
    Type: Grant
    Filed: December 3, 1974
    Date of Patent: January 6, 1976
    Assignee: SmithKline Corporation
    Inventors: Henry C. Caldwell, Bernard Loev