Patents by Inventor Bernard M. Babior

Bernard M. Babior has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stem cell and lymphocyte storage
    Patent number: 5912174
    Abstract: Methods of stabilizing lymphocytes and/or stem cells obtained from a mammal by suspending them in an aqueous medium comprising gelatin.
    Type: Grant
    Filed: November 20, 1995
    Date of Patent: June 15, 1999
    Inventors: David Scheer, Bernard M. Babior
  • Treatment of viscous mucous-associated diseases
    Patent number: 5908611
    Abstract: The present invention relates to therapeutic methods for treating diseases characterized by an accumulation of high molecular weight DNA in mucous, thereby contributing to the viscosity of the mucous. Such diseases include cystic fibrosis and chronic bronchitis. Treatment includes administration of weak organic acids to promote acidification of cells and consequently apoptosis-induced DNA fragmentation. The invention also relates to therapeutic apparatus for administering the acid compositions.
    Type: Grant
    Filed: May 5, 1995
    Date of Patent: June 1, 1999
    Assignee: The Scripps Research Institute
    Inventors: Roberta A. Gottlieb, Bernard M. Babior
  • Stabilization of leukocytes
    Patent number: 5369001
    Abstract: A aqueous stock solution for preserving human cells, particularly leukocytes, which includes 20-40% modified gelatin by weight in a physiologically acceptable buffer at pH4-7.5.
    Type: Grant
    Filed: September 28, 1992
    Date of Patent: November 29, 1994
    Inventor: Bernard M. Babior
  • Stabilization of leukocytes
    Patent number: 5211960
    Abstract: Preservation of leukocytes by suspending in storage medium containing modified fluid gelatin, plasma, and a non-toxic buffer. Preferred additives include heterocyclic bases which occur in nucleic acids, or nucleosides or nucleotides containing the same.
    Type: Grant
    Filed: November 15, 1989
    Date of Patent: May 18, 1993
    Assignee: Scripps Clinic and Research Foundation
    Inventor: Bernard M. Babior
  • Stabilization of leukocytes
    Patent number: 4923797
    Abstract: Preservation of leukocytes by suspending in storage medium containing modified fluid gelatin, plasma, and a non-toxic buffer. Preferred additives include heterocyclic bases which occur in nucleic acids, or nucleosides or nucleotides containing the same.
    Type: Grant
    Filed: November 29, 1988
    Date of Patent: May 8, 1990
    Assignee: President & Fellows of Harvard College
    Inventor: Bernard M. Babior
  • Stabilization of granulocytes
    Patent number: 4639373
    Abstract: Granulocytes are effectively preserved during storage for long periods of time without freezing by using as the storage medium a non-toxic buffer containing both gelatin and plasma.
    Type: Grant
    Filed: July 24, 1985
    Date of Patent: January 27, 1987
    Assignee: New England Medical Center Hospitals, Inc.
    Inventor: Bernard M. Babior
  • Stabilization of neutrophils and platelets
    Patent number: 4471051
    Abstract: Neutrophils and platelets from human blood are stabilized for storage and subsequent reconstitution for use by reacting with a chemical cross-linking agent having functional groups reactive to form covalent linkages with the neutrophils or platelets, the functional groups being covalently bonded to a molecular backbone including a group subject to cleavage under conditions which are non-destructive of the neutrophils or platelets. After storage at reduced temperature, the composition can be reconstituted by cleavage and substantially regains its original physiological properties.
    Type: Grant
    Filed: June 13, 1983
    Date of Patent: September 11, 1984
    Assignee: New England Medical Center Hospitals, Inc.
    Inventors: Bernard M. Babior, Irena I. Aviram