Patents by Inventor Bernard Malissen

Bernard Malissen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Laser-assisted intradermal administration of active substances
    Patent number: 10828354
    Abstract: A vaccine preparation comprising an antigen for use in the prophylactic or therapeutic treatment of a subject by intradermal administration through laser-generated micropores, wherein the antigen is linked to a binder of a dermal migratory antigen-presenting cell (APC); and a pharmaceutical preparation comprising an active substance for use in the prophylactic or therapeutic treatment of a subject by intradermal administration through laser-generated micropores, for regional delivery to a target location. The invention further relates to the laser-assisted intradermal administration of antigens accompanied by repeated chemotherapy.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: November 10, 2020
    Assignee: PANTEC BIOSOLUTIONS AG
    Inventors: Reinhard Braun, Dorothea Terhorst, Sandrine Henri, Bernard Malissen, Yoan J. Machado, Mellissa Mayr, Theresa Thalhamer, Veronika Höpflinger, Josef Thalhamer, Richard Weiss
  • TRANSGENIC ANIMALS AND METHODS OF MAKING RECOMBINANT ANTIBODIES
    Publication number: 20110185441
    Abstract: The present invention describes a means for obtaining cells which produce human, humanized or chimeric antibodies in commercially useful quantities. The invention permits high antibody producer cells to be selected and isolated from animals for use in culture to produce antibodies. The invention also provides methods for the affinity maturation of human, humanized or chimeric immunoglobulins.
    Type: Application
    Filed: April 8, 2011
    Publication date: July 28, 2011
    Applicants: INNATE PHARMA, S.A., INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
    Inventors: François Romagne, Bernard Malissen
  • Transgenic Animals and Methods of Making Recombinant Antibodies
    Publication number: 20080196112
    Abstract: The present invention concerns a means for obtaining cells which produce human, humanized or chimeric antibodies in commercially useful quantities. The invention permits high antibody producer cells to be selected and isolated from animals for use in culture to produce antibodies. The invention also provides methods for the affinity maturation of human, humanized or chimeric immunoglobulins.
    Type: Application
    Filed: April 28, 2006
    Publication date: August 14, 2008
    Applicants: Innate Pharma, S.A., INSERM (Institut National De La Sante Et De La Recherche Medicale)
    Inventors: Francois Romagne, Bernard Malissen
  • Mutated gene coding for a lat protein and the biological applications thereof
    Patent number: 7399901
    Abstract: The present invention relates to a mutated gene coding for a mutant LAT protein leading to exaggerated TH2 differentiation. The invention relates to biological structures containing the mutant, particularly non-human LAT gene, mutated animals, plasmids, chromosomal DNAs, embryos comprising the mutated gene, and applications thereof. The invention further relates to screening methods for drugs useful for treatment against asthma and allergy. Otherwise, the invention relates to methods for producing IgE antibodies.
    Type: Grant
    Filed: February 14, 2003
    Date of Patent: July 15, 2008
    Assignee: Institut National de la Sante et de la Recherche Medicale (Inserm)
    Inventors: Marie Malissen, Bernard Malissen, Enrique Aguado Vidal
  • Mutated gene coding for a lat protein and the biological applications thereof
    Publication number: 20050114914
    Abstract: The present invention relates to a mutated gene coding for a mutant LAT protein leading to an exaggerated TH2 differentiation. The invention relates to biological structures containing said mutant, particularly, non-human LAT gene mutated animals, plasmids, chromosomal DNA's, embryos comprising said mutated gene, and applications thereof. The invention further relates to screening method for drug useful for treatment against asthma and allergy. Otherwise, the invention relates to method for producing IgE antibodies.
    Type: Application
    Filed: February 14, 2003
    Publication date: May 26, 2005
    Inventors: Marie Malissen, Bernard Malissen