Patents by Inventor Bernard Martel
Bernard Martel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20260027264Abstract: The present disclosure relates to a hydrogel composition based on anionic cyclodextrin polymers and chitosan for use in the treatment of articular disorders. In particular, the hydrogel combines a pharmacological action, in particular an analgesic action, with a visco-supplementation (a lubricating effect).Type: ApplicationFiled: July 28, 2023Publication date: January 29, 2026Applicants: UNIVERSITE DE LILLE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, CENTRE HOSPITALIER UNIVERSITAIRE DE LILLE, Institut national de recherche pour l'agriculture, l'alimentation et l'environnement, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), CENTRALE LILLE INSTITUTInventors: Nicolas BLANCHEMAIN, Feng CHAI, Romain NICOT, Bernard MARTEL, Maria José GARCIA FERNANDEZ, Nicolas TABARY, Henry CHIJCHEAPAZA-FLORES
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Patent number: 11168183Abstract: The present invention concerns a method for producing a hydrogel comprising the following steps in succession: a first step (i) of providing at least one powder of an anionic polymer (A) and at least one chitosan powder (B) comprising amine functions (—NH2); a second step (ii) consisting in dry mixing at least the powders (A) and (B) from the first step in order to form a mixture of powders; a third step (iii) of suspending the mixture of powders obtained from the second step in an aqueous medium having a pH that can enable the anionic polymer (A) to be dissolved without dissolving the chitosan (B); a fourth step (iv) of adding an acid to the suspension obtained from the third step in order to form the hydrogel; or the third (iii) and fourth (iv) steps are replaced by a mixing fifth step (v), comprising mixing an acidified aqueous medium including at least one compound (C) comprising at least one unit of a hexose or a unit derived from a hexose, and/or at least one phosphate of said compound (C), with saidType: GrantFiled: July 1, 2016Date of Patent: November 9, 2021Assignees: UNIVERSITE DE LILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE LILLEInventors: Nicolas Blanchemain, Bernard Martel, Claudia Flores, Frédéric Cazaux, Feng Chai, Nicolas Tabary, Marco Lopez Heredia
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Publication number: 20210052772Abstract: The present invention relates to an implantable device comprising a textile component at least partially coated with a host polymer coating, said host polymer coating comprises a polymer of cyclodextrin(s) and/or derivatives of cyclodextrin(s) and/or inclusion complex(es) of cyclodextrin and/or inclusion complex(es) of cyclodextrin derivatives. Advantageously, said textile component comprises multifilament yarns and/or spun yarns made of fibers, at least a part of the filaments and/or fibers each having a diameter less than or equal to 25 micrometers.Type: ApplicationFiled: April 5, 2019Publication date: February 25, 2021Inventors: Guillaume VERMET, Bernard MARTEL, Nicolas BLANCHEMAIN, Stéphanie DEGOUTIN
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Publication number: 20180186939Abstract: The present invention concerns a method for producing a hydrogel comprising the following steps in succession: a first step (i) of providing at least one powder of an anionic polymer (A) and at least one chitosan powder (B) comprising amine functions (—NH2); a second step (ii) consisting in dry mixing at least the powders (A) and (B) from the first step in order to form a mixture of powders; a third step (iii) of suspending the mixture of powders obtained from the second step in an aqueous medium having a pH that can enable the anionic polymer (A) to be dissolved without dissolving the chitosan (B); a fourth step (iv) of adding an acid to the suspension obtained from the third step in order to form the hydrogel; or the third (iii) and fourth (iv) steps are replaced by a mixing fifth step (v), comprising mixing an acidified aqueous medium including at least one compound (C) comprising at least one unit of a hexose or a unit derived from a hexose, and/or at least one phosphate of said compound (C), with saidType: ApplicationFiled: July 1, 2016Publication date: July 5, 2018Inventors: Nicolas BLANCHEMAIN, Bernard MARTEL, Claudia FLORES, Frédéric CAZAUX, Feng CHAI, Nicolas TABARY, Marco LOPEZ HEREDIA
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Patent number: 8906403Abstract: A method for preparing a biomaterial containing at least one bioactive molecule from a base biomaterial, comprising the following successive operations carried out on the base biomaterial: a) application of a solid mixture of: cyclodextrin(s) and/or cyclodextrin derivative(s) and/or cyclodextrin inclusion complex(es) and/or cyclodextrin derivative inclusion complex(es), at least one poly(carboxylic) acid, and optionally a catalyst; b) heating at a temperature between 100° C. and 200° C. for a period of 1 to 60 minutes; c) washing with water; d) drying, wherein at least one bioactive agent is incorporated in the biomaterial by impregnation of the biomaterial after the drying step in a concentrated solution of the bioactive agent.Type: GrantFiled: November 15, 2005Date of Patent: December 9, 2014Assignees: Universite des Sciences et Technologies de Lille SAIC, Universite de Droit et SanteInventors: Bernard Martel, Nicolas Blanchemain, François Boschin, Stephan Haulon, Elisabeth Delcourt Debruyne, Michel Morcellet, Hartmut Friederich Hildebrand
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Publication number: 20080254094Abstract: The present invention relates to a method of preparation of a biomaterial containing at least one bioactive molecule from a base biomaterial, characterized by the following successive operations carried out on the aforesaid base biomaterial: a) application of a solid mixture of: cyclodextrin(s) and/or cyclodextrin derivative(s) and/or cyclodextrin inclusion complex(es) and/or cyclodextrin derivative inclusion complex(es), at least one poly(carboxylic) acid, and optionally a catalyst; b) heating at a temperature between 100° C. and 220° C. for a period of 1 to 60 minutes; c) washing with water; d) drying, and wherein at least one bioactive agent is incorporated in the biomaterial by impregnation of the biomaterial after the drying step in a concentrated solution of bioactive agent.Type: ApplicationFiled: November 15, 2005Publication date: October 16, 2008Applicant: UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE SInventors: Bernard Martel, Nicolas Blanchemain, Francois Boschin, Stephan Haulon, Elisabeth Delcourt Debruyne, Michel Morcellet, Hartmut Friedrich Hildebrand
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Patent number: 7048769Abstract: The present invention concerns a process for treating a fiber or a fiber-based material such as a yarn, a woven, knitted or nonwoven textile material, paper, or leather, to improve its adsorption properties, wherein the following successive operations are carried out on said fiber or said material: a) applying a solid mixture of cyclodextrin(s) and/or cyclodextrin derivative(s) and/or inclusion complex(es) of cyclodextrin and/or cyclodextrin derivatives, at least one poly(carboxylic) acid and/or at least one poly(carboxylic) acid anhydride and optionally a catalyst; b) heating to a temperature in the range 150° C. to 220° C.; c) washing with water; and d) drying. The present invention also concerns fibers or fiber-based materials with improved cation exchange properties and improved hydrophilic characteristics.Type: GrantFiled: February 15, 2000Date of Patent: May 23, 2006Assignee: Universite des Sciences et Technologies de LilleInventors: Marek Weltrowski, Michel Morcellet, Bernard Martel
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Patent number: 6660804Abstract: The present invention concerns a process for preparing copolymers of cyclodextrin(s) and/or cyclodextrin derivative(s), characterized by the following operations: (a) preparing a solid state mixture of cyclodextrin(s) and/or cyclodextrin derivative(s) and/or inclusion complex(es) of cyclodextrin(s) and/or cyclodextrin derivative(s) and a poly(carboxylic) acid and/or a poly(carboxylic) acid anhydride or a mixture of poly(carboxylic) acid(s) and/or poly(carboxylic) acid anhydride(s), and optionally, a catalyst; and (b) heating the solid mixture to a temperature in the range 100° C. to 200° C. for a period in the range 1 min to 60 min, preferably 30 min or substantially 30 min. The present invention also concerns soluble and insoluble compounds of cyclodextrin(s) and/or cyclodextrin derivative(s) or their inclusion complexes with at least one poly(carboxylic) acid.Type: GrantFiled: August 15, 2001Date of Patent: December 9, 2003Assignee: Universite des Sciences et Technologies de LilleInventors: Marek Weltrowski, Michel Morcellet, Bernard Martel
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Patent number: 4958765Abstract: A device is divulged for controlling and regulating the gas supply to the burner of a boiler or similar, which device comprises a piloted regulator (R) with a leak valve (8) for the gas flow. The burner is also fed with pressurized air and opening of the leak valve is slaved to the flow of this pressurized air so that the ratio between the two air and gas flows permanently has a value providing excellent combustion of the air-gas mixture in the burner.Type: GrantFiled: October 26, 1989Date of Patent: September 25, 1990Assignee: Chaffoteaux et MauryInventors: Joseph Le Mer, Bernard Martel
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Patent number: 4768478Abstract: A carburetor for internal combustion engines has an automatic starting device comprising a choke valve based toward opening by the air flow and toward closure by a temperature responsive bimetallic spiral when cold. A device further comprises a stop member an electrically controlled movable stop member having at least one active position in which it permits complete closure of the choke valve and a rest position in which it prevents closing movement of the choke valve beyond a predetermined position, and means arranged to bring said stop member into said active position, responsive to closure of the ignition switch and for being inhibited if after a sequence of operation of the cold engine during a period greater than a first threshold value, then rest condition of the engine for a period less than a second predetermined value.Type: GrantFiled: September 14, 1987Date of Patent: September 6, 1988Assignee: SolexInventor: Bernard Martel
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Patent number: 4662333Abstract: A carburetor is provided with an automatic starting device, more especially for motor car engines, comprising a butterfly valve controlled by the driver and -for starting up and cold running of the engine- an automatic starting device. This device comprises a start air valve (choke) and a wax capsule which controls the position of the air valve and the minimum opening position of the butterfly valve. The wax capsule is provided with a heating resistor and a temperature sensor. The starting device further comprises a computer having inputs connected to the temperature sensor and to sensors supplyng signals representative of the operating conditions of the engine. It controls the electric power applied to the heating resistor. The computer imposes on the butterfly valve and on the air valve a degree of opening which depends, on the one hand, on the temperature sensitive element during start up of the engine and, on the other hand, on the number of revolutions effected by this latter from start up.Type: GrantFiled: August 5, 1985Date of Patent: May 5, 1987Assignee: SolexInventor: Bernard Martel
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Patent number: 4279230Abstract: A fuel control system comprises a probe in contact with the exhaust gases, a circuit for supplying fuel and air to the engine, having a solenoid valve for metering at least the fuel flow, a closed-loop electronic control circuit connected to the probe and energizing the solenoid valve in dependence on the signal from the probe. The loop is opened responsive to predetermined operating conditions of the engine. Further means control the solenoid valve in dependence on another engine operating parameter during open-loop operation. A memory is provided for storing a value representative of the control of the solenoid valve means during closed-loop operation.Type: GrantFiled: May 2, 1978Date of Patent: July 21, 1981Assignee: Societe Industrielle de Brevets et D'Etudes S.I.B.E.Inventors: Philippe Bauer, Jean Lamy, Bernard Martel
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Patent number: 4227496Abstract: A fuel supply device for an internal combustion engine having at least two groups of combustion chambers, each group having a separate exhaust pipe, comprises a carburettor which delivers a mixture whose air/fuel ratio is adjusted responsive to the composition of the exhaust gases of the "richer" group. The carburettor is connected to a manifold having two branches each associated with one group. The branch feeding the "leaner" group is provided with an air/fuel ratio correction circuit comprising a solenoid valve controlled by a circuit whose input detector is located in the exhaust pipe of the "leaner" group.Type: GrantFiled: November 8, 1978Date of Patent: October 14, 1980Assignee: Societe Industrielle de Brevets et d'Etudes S.I.B.E.Inventor: Bernard Martel