Patents by Inventor Bernard O. Palsson

Bernard O. Palsson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR MODELING HUMAN METABOLISM
    Publication number: 20110213603
    Abstract: The present invention provides Homo sapiens Recon 1, a manually assembled, functionally validated, bottom-up reconstruction of human metabolism. Recon 1's 1496 genes, 2004 proteins, 2766 metabolites, and 3311 biochemical and transport reactions were extracted from more than 50 years of legacy biochemical knowledge and Build 35 of the human genome sequence.
    Type: Application
    Filed: August 26, 2010
    Publication date: September 1, 2011
    Applicant: The Regents of the University of California
    Inventors: Bernard O. Palsson, Natalie Duarte, Scott Becker, Neema Jamshidi
  • Methods and Systems to Identify Operational Reaction Pathways
    Publication number: 20100317007
    Abstract: The present invention provides a method for identifying an operational reaction pathway of a biosystem. The method includes (a) providing a set of systemic reaction pathways through a reaction network representing said biosystem; (b) providing a set of phenomenological reaction pathways of said biosystem, and (c) comparing said set of systemic reaction pathways with said set of phenomenological reaction pathways, wherein a pathway common to said sets is an operational reaction pathway of said biosystem. Also described is a method of refining a biosystem reaction network; a method of reconciling biosystem data sets; a method of determining the effect of a genetic polymorphism on whole cell function; and a method of diagnosing a genetic polymorphism-mediated pathology.
    Type: Application
    Filed: May 27, 2010
    Publication date: December 16, 2010
    Inventors: Bernard O. Palsson, Markus W. Covert, Markus Herrgard
  • Compositions and methods for modeling human metabolism
    Patent number: 7788041
    Abstract: The present invention provides Homo sapiens Recon 1, a manually assembled, functionally validated, bottom-up reconstruction of human metabolism. Recon 1's 1496 genes, 2004 proteins, 2766 metabolites, and 3311 biochemical and transport reactions were extracted from more than 50 years of legacy biochemical knowledge and Build 35 of the human genome sequence.
    Type: Grant
    Filed: October 3, 2007
    Date of Patent: August 31, 2010
    Assignee: The Regents of the University of California
    Inventors: Bernard O. Palsson, Natalie Duarte, Scott Becker, Neema Jamshidi
  • COMPOSITIONS AND METHODS FOR MODELING HUMAN METABOLISM
    Publication number: 20080133196
    Abstract: The present invention provides Homo sapiens Recon 1, a manually assembled, functionally validated, bottom-up reconstruction of human metabolism. Recon 1's 1496 genes, 2004 proteins, 2766 metabolites, and 3311 biochemical and transport reactions were extracted from more than 50 years of legacy biochemical knowledge and Build 35 of the human genome sequence.
    Type: Application
    Filed: October 3, 2007
    Publication date: June 5, 2008
    Applicant: The Regents of the University of California
    Inventors: Bernard O. Palsson, Natalie Duarte, Scott Becker, Neema Jamshidi