Patents by Inventor Bernard Ravina

Bernard Ravina has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11975056
    Abstract: The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
    Type: Grant
    Filed: May 3, 2021
    Date of Patent: May 7, 2024
    Assignee: Voyager Therapeutics, Inc.
    Inventors: Robert Kotin, Adrian Philip Kells, Bernard Ravina
  • Patent number: 11759506
    Abstract: The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
    Type: Grant
    Filed: July 26, 2019
    Date of Patent: September 19, 2023
    Assignee: Voyager Therapeutics, Inc.
    Inventors: Maria Scheel, Bernard Ravina
  • Publication number: 20230165847
    Abstract: Described herein, in part, are methods useful for preventing and/or treating a disease or condition relating to aberrant function or activity of a T-type calcium channel, such as psychiatric disorders (e.g., mood disorder (e.g., major depressive disorder)), pain, tremor (e.g., essential tremor), seizures (e.g., absence seizures), epilepsy, or an epilepsy syndrome (e.g., juvenile myoclonic epilepsy). The present invention further comprises methods for modulating the function of a T-type calcium channel and methods of administering a titrated dosage of a T-type calcium channel antagonist.
    Type: Application
    Filed: October 27, 2022
    Publication date: June 1, 2023
    Inventors: Kiran Reddy, Gabriel Maurice Belfort, Bernard Ravina, Marion Wittmann
  • Publication number: 20210338786
    Abstract: The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
    Type: Application
    Filed: May 3, 2021
    Publication date: November 4, 2021
    Inventors: Robert Kotin, Adrian Philip Kells, Bernard Ravina
  • Publication number: 20210198691
    Abstract: The present disclosure relates to methods, formulations and devices for the delivery and therapeutic administration of polynucleotides encoding AADC. The present disclosure relates to methods, formulations and devices for the delivery and therapeutic administration of AAV vectors which include polynucleotides encoding AADC. The present disclosure relates to methods, formulations and devices for the delivery and therapeutic administration of polynucleotides encoding AADC in the treatment of neurological diseases, disorders and conditions, including Parkinson's Disease.
    Type: Application
    Filed: May 15, 2019
    Publication date: July 1, 2021
    Applicant: Voyager Therapeutics, Inc.
    Inventors: Bernard RAVINA, Adrian Philip KELLS
  • Patent number: 11027000
    Abstract: The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
    Type: Grant
    Filed: August 14, 2019
    Date of Patent: June 8, 2021
    Assignee: Voyager Therapeutics, Inc.
    Inventors: Robert Kotin, Adrian Philip Kells, Bernard Ravina
  • Publication number: 20190358306
    Abstract: The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
    Type: Application
    Filed: August 14, 2019
    Publication date: November 28, 2019
    Inventors: Robert Kotin, Adrian Philip Kells, Bernard Ravina
  • Publication number: 20190343937
    Abstract: The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
    Type: Application
    Filed: July 26, 2019
    Publication date: November 14, 2019
    Inventors: Maria Scheel, Bernard Ravina
  • Patent number: 10335466
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: July 2, 2019
    Assignee: VOYAGER THERAPEUTICS, INC.
    Inventors: Robert Kotin, Adrian Philip Kells, Bernard Ravina
  • Publication number: 20190060425
    Abstract: The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
    Type: Application
    Filed: November 8, 2018
    Publication date: February 28, 2019
    Inventors: Maria Scheel, Bernard Ravina
  • Publication number: 20190054158
    Abstract: The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment, prophylaxis, palliation or amelioration of diseases, conditions and/or symptoms resulting from AADC deficiency and related inborn errors of neurotransmitter metabolism.
    Type: Application
    Filed: November 2, 2018
    Publication date: February 21, 2019
    Inventors: Robert Kotin, Adrian Philip Kells, Bernard Ravina
  • Publication number: 20190008933
    Abstract: The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
    Type: Application
    Filed: September 20, 2018
    Publication date: January 10, 2019
    Inventors: Robert Kotin, Adrian Philip Kells, Bernard Ravina
  • Publication number: 20190008932
    Abstract: The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
    Type: Application
    Filed: September 20, 2018
    Publication date: January 10, 2019
    Inventors: Robert Kotin, Adrian Philip Kells, Bernard Ravina
  • Publication number: 20190008931
    Abstract: The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
    Type: Application
    Filed: September 20, 2018
    Publication date: January 10, 2019
    Inventors: Robert Kotin, Adrian Philip Kells, Bernard Ravina
  • Publication number: 20190000940
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment, prophylaxis, palliation or amelioration of diseases, conditions and/or symptoms resulting from AADC deficiency and related inborn errors of neurotransmitter metabolism.
    Type: Application
    Filed: July 29, 2016
    Publication date: January 3, 2019
    Inventors: Robert Kotin, Adrian Philip Kells, Bernard Ravina
  • Publication number: 20170333538
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
    Type: Application
    Filed: November 5, 2015
    Publication date: November 23, 2017
    Inventors: Robert Kotin, Adrian Philip Kells, Bernard Ravina