Patents by Inventor Bernard Rubin

Bernard Rubin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of protecting against and/or treating ulcerative gastrointestinal conditions using a thromboxane A.sub.2 receptor antagonist and combination useful in preventing and/or treating ulcers and/or inflammation
    Patent number: 5312818
    Abstract: A method is provided for protecting against and/or treating ulcerative gastrointestinal conditions, including anti-inflammatory drug-induced gastrointestinal ulcers, using a thromboxane A.sub.2 receptor antagonist. In addition, a combination is provided which includes a thromboxane A.sub.2 receptor antagonist and an anti-inflammatory agent which combination may be used to treat inflammatory conditions, such as arthritis, while inhibiting formation of and/or treating gastrointestinal ulcers.
    Type: Grant
    Filed: December 23, 1992
    Date of Patent: May 17, 1994
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Bernard Rubin, Martin L. Ogletree, Eugene H. O'Keefe, A. K. Gunnar Aberg
  • Method of treating hypertension and medicaments therefor
    Patent number: 4217347
    Abstract: A method for reducing blood pressure comprises administering a combination of a diuretic compound and a compound having the general formula ##STR1##
    Type: Grant
    Filed: November 9, 1978
    Date of Patent: August 12, 1980
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Zola P. Horovitz, Bernard Rubin
  • Method of stabilizing an injectable composition of a cholecystokinin active octapeptide
    Patent number: 3937819
    Abstract: A stable composition of the sulfated octapeptide, ##EQU1## having cholecystokinin activity, is obtained by lyophilizing an aqueous solution of the octapeptide and NaCl.
    Type: Grant
    Filed: July 22, 1974
    Date of Patent: February 10, 1976
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Miguel Angel Ondetti, Charles Riffkin, Bernard Rubin, Aaron L. Weiss