Patents by Inventor Bernard Schmidt

Bernard Schmidt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aryl-substituted alkoxycarbonyl-1,4-dihydropyridine-5-carboxylic acid esters
    Patent number: 5658934
    Abstract: The invention relates to new aryl-substituted alkoxycarbonyl-1,4-dihydropyridine-5-carboxylic acid esters, processes for their preparation and their use in medicaments, in particular as agents having a cerebral action.
    Type: Grant
    Filed: December 5, 1994
    Date of Patent: August 19, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Heinrich Meier, Wolfgang Hartwig, Bodo Junge, Ulrich Niewohner, Rudolf Schohe-Loop, Zhan Gao, Bernard Schmidt, Maarten de Jonge, Teunis Schuurman
  • Use of substituted amines for the treatment of brain function disorders
    Patent number: 5547965
    Abstract: The invention relates to the use of substituted amines for the treatment and prevention of brain function disorders. The substituted amines are suitable on the basis of their properties as agonistic or antagonistic ligands for nicotinergic receptors, in particular for the treatment and prevention of senile and presenile dementia and dementia of the Alzheimer type, and of depressions.
    Type: Grant
    Filed: April 19, 1995
    Date of Patent: August 20, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Bernd-Wieland Kr uger, Fritz Maurer, Christoph Methfessel, Klaus Tietjen, Alfred Maelicke, Bernard Schmidt, Kozo Shiokawa
  • 4-heterocyclyl-substituted dihydropyridines
    Patent number: 5502064
    Abstract: 4-Heterocyclyl-substituted dihydropyridines are prepared by reacting appropriate aldehydes with .beta.-keto esters and aminocrotonic acid esters, or by esterifying 4-hetero-cyclyl-substituted dihydropyridinecarboxylic acids. The 4-heterocyclyl-substituted dihydropyridines can be employed in medicaments, in particular for the treatment of disorders of the central nervous system.
    Type: Grant
    Filed: October 22, 1993
    Date of Patent: March 26, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Bodo Junge, Wolfgang Hartwig, Heinrich Meier, Rudolf Schohe-Loop, Zhan Gao, Bernard Schmidt, Maarten de Jonge, Teunis Schuurman
  • 4-heterocyclophenyl-substituted dihydropyridines
    Patent number: 5403849
    Abstract: 4-Heterocyclophenyl-substituted dihydropyridines ##STR1## are prepared either by reacting suitable aldehydes with amino esters and .beta.-keto esters, or preparing the heterocyclic substituents of the 4-phenyl by cyclization of corresponding amidines or hydrazides, or esterifying dihydropyridinecarboxylic acids, which are already substituted by heterocyclic radicals, with corresponding alcohols. The 4-heterocyclophenyl-substituted dihydropyridines can be employed in medicaments, in particular for treatment of diseases of the central nervous system.
    Type: Grant
    Filed: October 22, 1993
    Date of Patent: April 4, 1995
    Assignee: Bayer Aktiengesellschaft
    Inventors: Rudolf Schohe-Loop, Wolfgang Hartwig, Bodo Junge, Heinrich Meier, Zhan Gao, Bernard Schmidt, Maarten de Jonge, Teunis Schuurman