Abstract: A composition comprises an aqueous dispersion of particles (p) of mean hydrodynamic diameter between 50 and 5000 nm. The particles contain (A) polymers based on cyclodextrin units, comprising on average at least four cyclodextrin units within their structure; and (B) macromolecules of polysaccharides comprising groups G capable of forming inclusion complexes with the cyclodextrins present in the structure of the polymers (A), with an average number of groups G per polysaccharide macromolecule at least equal to three. The compounds (A) and (B) are water-soluble in the isolated state. A method is also provided which relates to the preparation of these compositions, as well as their use in order to achieve the encapsulation of compounds such as active substances.

Abstract: The present invention relates to a composition comprising an aqueous dispersion of particles (p) of mean hydrodynamic diameter between 50 and 5000 nm, the said particles containing in association: (A) polymers based on cyclodextrin units, comprising on average at least 4 cyclodextrin units within their structure; and (B) macromolecules of polysaccharides comprising groups G capable of forming inclusion complexes with the cyclodextrins present in the structure of the said polymers (A), with an average number of groups G per polysaccharide macromolecule at least equal to 3, the said compounds (A) and (B) being water-soluble in the isolated state. The invention also relates to the method of preparation of these compositions, as well as their use in order to achieve the encapsulation of compounds such as active substances.

Abstract: Active chemical sensor with optical fiber and its production process.The chemical sensor according to the invention makes it possible to measure a given quantity or magnitude of a fluid. It has a chemical reagent suitable for the measurement and for reacting with the fluid, a support means (20a, 28) for the reagent and a single optical fiber (20) for supplying light to the reagent and recovering the light reflected by the reagent, said sensor being characterized in that the support means incorporates a vinyl imidazole polymer or copolymer film (28) in which the reagent is immobilized, said polymer being in particular directly grafted on to one of the ends (20a) of the optical fiber (20).

Abstract: The invention relates to novel thiosulfonate derivatives of general formu a:R--S--SO.sub.2 --R.sub.1in which R represents a 1H-imidazol-2-yl, quinolin-2-yl, 5-amino-1,3,4-thiadizol-2-yl or 4,5-dihydro-thiazol-2-yl radical and R.sub.1 represents a lower alkyl, (hydroxy)lower alkyl, phenyl, (lower alkyl) phenyl, (hydroxy lower alkyl) phenyl, (lower alkanoyl) phenyl or quinolin-8-yl radical.The thiosulfonate derivatives in question exert an inhibitory action with respect to the malformation or destruction of red blood corpuscules due to a genetic modification of haemoglobin or to parasites and can, therefore, be used in the treatment of drepanocytosis, malaria and babebiosis.

Abstract: The invention relates to pharmaceutical or veterinary compositions for initing the malformation or destruction of red blood corpuscules due to a genetic modification of haemoglobin or to parasites, compositions comprising, as active ingredient, at least one thiosulfonate derivative of general formula:R--S--SO.sub.2 --R.sub.1in which R represents a 1-methyl-imidazol-2-yl, 1H-benzimidazol-2-yl or benzoxazol-2-yl radical and R.sub.1 represents a lower alkyl, (hydroxy) lower alkyl, lower alkanoyl, phenyl, (lower alkyl) phenyl, (hydroxy lower alkyl) phenyl, (lower alkanoyl) phenyl or quinolin-8-yl radical.The compositions in question can be used in the treatment of drepanocytosis, malaria and babebiosis.