Patents by Inventor Bernard Thienpont

Bernard Thienpont has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Markers for determining tumor hypoxia
    Patent number: 11814688
    Abstract: The present application relates to the field of cancer, particular to hypoxic tumors. It was found that hypoxia is an important driver for hypermethylation of (promoters of) tumor suppressor genes. As this hypermethylation is a stable signature that is also present in circulating tumor DNA in peripheral blood, detecting this methylation pattern is a surrogate marker for tumor hypoxia. This can be used to adapt therapy as well.
    Type: Grant
    Filed: April 25, 2022
    Date of Patent: November 14, 2023
    Assignees: VIB VZW, Katholieke Universiteit Leuven, K.U. Leuven R & D, Life Sciences Research Partners VZW
    Inventors: Diether Lambrechts, Bernard Thienpont
  • Markers for Determining Tumor Hypoxia
    Publication number: 20220259677
    Abstract: The present application relates to the field of cancer, particular to hypoxic tumors. It was found that hypoxia is an important driver for hypermethylation of (promoters of) tumor suppressor genes. As this hypermethylation is a stable signature that is also present in circulating tumor DNA in peripheral blood, detecting this methylation pattern is a surrogate marker for tumor hypoxia. This can be used to adapt therapy as well.
    Type: Application
    Filed: April 25, 2022
    Publication date: August 18, 2022
    Applicants: VIB VZW, Katholieke Universiteit Leuven, K.U. Leuven R&D, Life Sciences Research Partners VZW
    Inventors: Diether LAMBRECHTS, Bernard THIENPONT
  • Markers for Determining Tumor Hypoxia
    Publication number: 20180051345
    Abstract: The present application relates to the field of cancer, particular to hypoxic tumors. It was found that hypoxia is an important driver for hypermethylation of (promoters of) tumor suppressor genes. As this hypermethylation is a stable signature that is also present in circulating tumor DNA in peripheral blood, detecting this methylation pattern is a surrogate marker for tumor hypoxia. This can be used to adapt therapy as well.
    Type: Application
    Filed: March 4, 2016
    Publication date: February 22, 2018
    Applicants: VIB VZW, KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D, LIFE SCIENCES RESEARCH PARTNERS VZW
    Inventors: Diether LAMBRECHTS, Bernard THIENPONT
  • Method and devices for processing fresh foodstuffs
    Patent number: 5500238
    Abstract: The present invention relates to a method for processing fresh foodstuffs in large quantities and in bulk, such as fruit and vegetables but also other types of foodstuffs such as pasta, fish, meat, etc. in order to allow them to be preserved for a long period of time whilst keeping their organoleptic characteristics. The invention also extends to devices for implementing this method.
    Type: Grant
    Filed: July 28, 1994
    Date of Patent: March 19, 1996
    Inventor: Bernard Thienpont