Abstract: A method of preparing custom corneal tissue in response to a request for the custom corneal tissue that includes specifications specifying the size and shape of the custom corneal tissue. After the request is received, donor eye tissue is selected from a plurality of donor eye tissues. The plurality of donor eye tissues may be stored by an eye bank facility. Next, preparations are made to cut the selected donor eye tissue in accordance with the specifications included in the request. A set of parameters is determined from the specifications and used to design a cutting path. The selected donor eye tissue is cut along the cutting path to produce the custom corneal tissue. The custom corneal tissue is separated from the selected donor eye tissue, packaged, and provided to the requestor.