Abstract: The present invention relates to derivatives of L-Tyrosyl-L-Arginine and the use of said derivatives in the prevention and/or treatment of a tau-induced cytotoxicity.

Abstract: The present invention relates to a compound of formula (I) wherein X is hydrogen, R1, R1C(O), R1CO2, or a COX2 inhibitor, wherein R1 is C1-20 alkyl, aryl, arylalkyl, alkyloxy or arylalkyloxy; wherein Y is OR2, NHR3N(R3)2, or a COX inhibitor; wherein R2 is hydrogen or C1-20 alkyl and each R3 is independently hydrogen or a C1-4 alkyl; wherein T is OR4, NHR5N(R5)2, or a COX inhibitor wherein R4 is hydrogen or C1-20 alkyl and each R5 is independently hydrogen or a C1-4 alkyl; wherein Z is hydrogen, R6, R6C(O), R6CO2, or a COX2 inhibitor; wherein R6 is C1-20 alkyl, aryl, arylalkyl, alkyloxy or arylalkyloxy; with the proviso wherein when X and Z are hydrogen and T is OH, Y is not OH; for use in the prevention and/or treatment of pain wherein said compound is provided for systemic administration.

Abstract: Sizing agents, some of which are known compounds and some of which are novel aromatic compounds which contain in the aromatic nucleus a single hydrophobic substituent containing at least 5 carbon atoms and at least one anionic group, said hydrophobic substituent being linked to the aromatic nucleus through an ester, amide, urethane or urea bridge, with the CO group of ester and amide bridges being attached to the hydrophobic radical and a methylene group being optionally present between said bridges and the aromatic nucleus, are particularly suitable, together with commercially available retention aids, for use in a process for the mass sizing of paper or cardboard or for the surface sizing of paper.

Abstract: A process for protecting keratinous material with the aid of phenoxytrifluoromethanesulfonanilides, some of which are novel, from pests that feed on keratin, said phenoxytrifluoromethanesulfonanilides having the formula ##STR1## wherein R.sub.1 and R.sub.2, each independently of the other, are halogen, haloalkyl, alkyl, nitro, cyano, alkoxy or haloalkoxy,n is 0 or a value from 1 to 4 andm is 0 or a value from 1 to 3, with the proviso that ifn or m>1, the substituents R.sub.1 and R.sub.2 may be identical or different, and that at least one substituent selected from the group consisting of halogen, haloalkyl and haloalkoxy is present in the molecule.The preparation of these compounds and the use thereof as active ingredients of compositions providing a mothproof and beetle-resistant finish are also described herein.

Abstract: The invention relates to a composition for protecting keratinous material, in particular woollen textiles, from attack by pests that feed on keratin, in particular moth and beetle larvae, which composition contains, as active ingredient combination, a specifically substituted 5-(pyridyloxyphenylcarbamoyl)barbituric acid or a salt thereof and a synthetic pyrethroid, as well as to a process comprising the use of this active ingredient combination for providing said material with a protective finish against attack by pests that feed on keratin.

Abstract: A composition for protecting keratin material, in particular woolen textiles, against attack by keratin pests, in particular moth and beetle larvae, which contains a specifically substituted 5-phenylcarbamoylbarbituric acid or a salt thereof and a synthetic pyrethroid as the active compound combination, is described, as well as a process, using the said active compound combination, for imparting a finish to the said material against attack by keratin pests.

Abstract: A method of protecting keratinous material, especially wool, from attack by insects that feed on keratin, which comprises treating said material with compounds of the formula ##STR1## wherein X is oxygen or sulfur, each of R.sub.1 and R.sub.2 independently is alkyl, alkenyl, benzyl or unsubstituted or substituted phenyl, R.sub.3 is halogen, nitro or trihalomethyl, R.sub.4 is hydrogen, halogen or trihalomethyl, and R.sub.5 is hydrogen, halogen, methyl or methoxy. The invention also provides novel compounds of the formula (1) wherein at least one of R.sub.1 and R.sub.2 is phenyl or substituted phenyl and X is oxygen as well as compositions containing the compounds of the formula (1) and compositions which, in addition to the compounds of formula (1), also contain synthetic pyrethroids, esters of .alpha.-alkyl-substituted phenylacetic acids or substituted sulfanilides.

Abstract: A method of protecting keratinous material, especially wool, from attack by insects that feed on keratin, which comprises treating said material with compounds of the formula ##STR1## wherein X is oxygen or sulfur, each of R.sub.1 and R.sub.2 independently is alkyl, alkenyl, benzyl or unsubstituted or substituted phenyl, R.sub.3 is halogen, nitro or trihalomethyl, R.sub.4 is hydrogen, halogen or trihalomethyl, and R.sub.5 is hydrogen, halogen, methyl or methoxy. The invention also provides novel compounds of the formula (1) wherein at least one of R.sub.1 and R.sub.2 is phenyl or substituted phenyl and X is oxygen as well as compositions containing the compounds of the formula (1) and compositions which, in addition to the compounds of formula (1), also contain synthetic pyrethroids, esters of .alpha.-alkyl-substituted phenylacetic acids or substituted sulfanilides.

Abstract: A method of protecting keratinous material from attack by insects that feed on keratin and from feeding damage, which comprises treating the material to be protected with compounds of the formula ##STR1## wherein each of R.sub.1 and R.sub.2 independently represents hydrogen, fluorine, chlorine, bromine, alkyl of 1 to 4 carbon atoms or alkoxy of 1 to 4 carbon atoms, or R.sub.1 and R.sub.2 in the ortho-position to each other together represent the methylenedioxy radical, and R.sub.3 represents hydrogen, cyano, --C.tbd.CH of --CH.dbd.CH.sub.2.

Abstract: Novel stilbene compounds of the formula ##STR1## in which A is the radical ##STR2## in which R.sub.1 is hydrogen or chlorine and R.sub.2 is hydrogen or alkyl, Z is hydrogen, chlorine or phenyl and R.sub.3 is hydrogen, alkyl or chlorine, as well as their use in a process for optically brightening organic material are described.

Abstract: Novel stilbene compounds of the formula ##STR1## in which R.sub.1 and R.sub.2 independently of one another are hydrogen or chlorine and A is a mono-nuclear or poly-nuclear aromatic heterocyclic structure which contains oxygen atoms or oxygen and nitrogen atoms and is unsubstituted or substituted by non-chromophoric substituents, as well as their use in a process for optically brightening organic material are disclosed.