Abstract: A monofilament (100) for producing an Nb3 Sn-containing superconductor wire (33) includes a powder core (1) with an Sn-containing powder, a reaction tube (3) composed of an Nb alloy that includes Nb and at least one further alloy component X. The powder core is disposed within the reaction tube. The monofilament also includes at least two sources (4) for at least one partner component Pk. A respective source includes one or more source structures at a unitary radial position in the monofilament. The source structures are at different radial positions. The alloy component X and the partner component Pk form precipitates XPk on reaction annealing of the monofilament in which Sn from the powder core and Nb from the reaction tube react to produce Nb3 Sn. The powder core is disposed in a moderation tube, which is disposed within the reaction tube. This provides a monofilament with improved current carrying capacity.

Abstract: A deep learning system is used to predict crop characteristics from inputs that include crop variety features, environmental features, and field management features. The deep learning system includes domain-specific modules for each category of features. Some of the domain-specific modules are implemented as convolutional neural networks (CNN) while others are implemented as fully-connected neural networks. Interactions between different domains are captured with cross attention between respective embeddings. Embeddings from the multiple domain-specific modules are concatenated to create a deep neural network (DNN). The prediction generated by the DNN is a characteristic of the crop such as yield, height, or disease resistance. The DNN can be used to select a crop variety for planting in a field. For a crop that is planted, the DNN may be used to select a field management technique.

Abstract: A method of sample analysis is provided. In certain embodiments, the method may comprise: a) contacting under primer extension conditions a genomic sample comprising a test genome with a set of at least ten sequence-specific primers that are complementary to sites in only one strand of a reference chromosomal region, to produce primer extension products, and b) analyzing the primer extension products to identify a chromosomal rearrangement in the test genome.

Abstract: A method of sample analysis is provided. In certain embodiments, the method may comprise: a) contacting under primer extension conditions a genomic sample comprising a test genome with a set of at least ten sequence-specific primers that are complementary to sites in only one strand of a reference chromosomal region, to produce primer extension products, and b) analyzing the primer extension products to identify a chromosomal rearrangement in the test genome.

Abstract: The present invention provides methods, kits, and compositions for the detection of an analyte. The invention is particularly suited for the detection and quantification of an analyte in a sample. In the methods of the invention a complex is formed between an analyte specific binding agent and an analyte. The analyte specific agents are coupled to an enzyme possessing an activity that produces a PCR template indicative of the presence of the analyte. Amplification and detection of the PCR template yields a sensitive and quantitative measurement of analyte concentration.

Abstract: Provided is an improved method for controlling gene expression in vivo through the use of a gene switch comprising one or more aptamer sequences operably linked to or incorporated into the untranslated regions (UTRs) of a transgene or nucleotide sequence of interest. Also provided are expression vectors having aptamer sequences located within the 3? UTR, the 5? UTR and between the genes of a multicistronic mRNA, as well as methods of using the expression vectors for controlling or regulating gene expression.