Patents by Inventor Bernd Knabe

Bernd Knabe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4201779
    Abstract: Cephem derivatives of the formula ##STR1## in which R.sup.1 denotes hydrogen or low-molecular alkoxy, R.sup.2 denotes hydrogen, optionally substituted alkyl, phthalide or a cation, X denotes sulfur, oxygen or CH.sub.2 and A denotes hydrogen, alkoxy, halogen or a group --CH.sub.2 Y, in which Y represents hydrogen, acyloxy, alkoxy, optionally substituted carbamoyloxy or a group --SR.sup.3, in which R.sup.3 can represent acyl, alkyl or an optionally substituted 5-membered or 6-membered heterocyclic structure are disclosed as valuable antibiotics which are well suited for combating Gram-positive and in particular Gram-negative infections and also have an unexpectedly good action against penicillinase-forming staphylococci.
    Type: Grant
    Filed: March 9, 1978
    Date of Patent: May 6, 1980
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Dieter Bormann, Bernd Knabe, Elmar Schrinner, Manfred Worm
  • Patent number: 4174397
    Abstract: Thiazolidine derivatives of the formula I ##STR1## in which the substituents R.sup.1 to R.sup.7 have the meanings as indicated in the following and which have in the free form or in the form of their non toxic acid addition salts valuable pharmaceutical properties, processes for preparing them, pharmaceutical preparations on the basis of these compounds and their use as medicines.
    Type: Grant
    Filed: September 6, 1977
    Date of Patent: November 13, 1979
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Bernd Knabe, Hans-Jochen Lang, Ernold Granzer
  • Patent number: 4024274
    Abstract: N-Cycloalkyl-benzylamine derivatives of the formula ##STR1## in which R.sup.1 represents hydrogen or lower alkyl of 1 to 4 carbon atoms, R.sup.2 represents a cycloalkyl radical of a total of 7 to 12 carbon atoms which may be alkyl-substituted and may contain hydrocarbon bridges of 1 to 3 carbon atoms, R.sup.3 represents hydrogen, alkoxy of 1 to 4 carbon atoms, R.sup.4 represents hydrogen or alkoxy of 1 to 4 carbon atoms or halogen, and R.sup.5 represents alkoxy of 1 to 4 carbon atoms, methylene dioxy, ethylene dioxy, benzyloxy or halogen, and the physiologically tolerated salts thereof are disclosed as having diuretic and saluretic activity.
    Type: Grant
    Filed: January 21, 1975
    Date of Patent: May 17, 1977
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Eike Druckrey, Bernd Knabe, Hans-Jochen Lang, Milos Babej, Roman Muschaweck
  • Patent number: 4016159
    Abstract: Acylamino-cephem-carboxylic acids of the formula I ##STR1## in which R.sup.1, R.sup.2 and R.sup.3 represent hydrogen or alkyl, R.sup.1 and R.sup.2 or R.sup.2 and R.sup.3 together may form an alkylene radical which may be substituted, X represents a single bond or NH, A represents a phenylene or thienylene radical which may be substituted, Y represents a single bond or oxygen and Z represents a 5- or 6-membered ring which may be substituted and which may be bound to an anellated ring system, and their physiologically tolerated salts and esters, a process for preparing these compounds and preparations containing them.
    Type: Grant
    Filed: November 27, 1974
    Date of Patent: April 5, 1977
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Dieter Bormann, Bernd Knabe, Elmar Schrinner, Manfred Worm