Publication number: 20050070570
Abstract: The invention relates to compounds having the Formula (I) or a salt, or a physiologically functional derivative, or a prodrug thereof, wherein Z is carbonyl or sulfonyl; R1 is alkyl, alkenyl, alkynyl, aryl, H, halogen, haloalkyl, haloalkoxy, hydroxyalkyl, cycloalkyl or heteroaryl; R2 is H, OH, —CH2—SO2-alkyl, —CH2—SO2-cycloalkyl, —CH2—SO2-aryl, —CH2—SO2-heteroaryl, alkylamine, alkenylamine, alkynylamine, cycloalkylamine, arylamine, heteroarylamine, aryl, haloalkyl, haloalkoxy, hydroxyalkyl, cycloalkyl, heteroaryl or a linear or branched alkyl, alkenyl, alkynyl, which can optionally be substituted by one or more substituents R3; R3 is H, alkyl, alkenyl, alkynyl, cycloalkyl, —CO2R4, —CONHR4, —CONR4R4, —CR4O, —SO2R4, —NR4—CO—R4, alkoxy, alkylthio, —OH, —SH, —O-aryl, —O-cycloalkyl, —S-aryl, —S-cycloalkyl, hydroxyalkyl, halogen, haloalkyl, haloalkoxy, CN, NO2, hydroxyalkylamine, aminoalkyl, alkylamine, aryl or heteroaryl; R4 is H, halogen, alkyl, alkenyl, alkynyl, cycloalkyl, alkoxy, alkylthio, —O-aryl,
Type:
Application
Filed:
June 18, 2004
Publication date:
March 31, 2005
Applicant:
4SC AG
Inventors:
Gabriel Garcia, Wael Saeb, Bernd Kramer