Patents by Inventor Bernd Otterbach

Bernd Otterbach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL POLY(ADP-RIBOSE) POLYMERASE GENES
    Publication number: 20160010067
    Abstract: The invention relates to poly(ADP-ribose)polymerase (PARP) homologs which have an amino acid sequence which has a) a functional NAD+ binding domain and b) no zinc finger sequence motif of the general formula CX2CXmHX2C in which m is an integral value from 28 or 30, and the X radicals are, independently of one another, any amino acid; and the functional equivalents thereof; nucleic acids coding therefor; antibodies with specificity for the novel protein; pharmaceutical and gene therapy compositions which comprise products according to the invention; methods for the analytical determination of the proteins and nucleic acids according to the invention; methods for identifying effectors or binding partners of the proteins according to the invention; novel PARP effectors; and methods for determining the activity of such effectors.
    Type: Application
    Filed: June 5, 2015
    Publication date: January 14, 2016
    Inventors: Michael Kock, Thomas HöGER, Burkhard Kröger, Bernd Otterbach, Wilfried Lubisch, Hans-Georg Lemaire
  • Poly(ADP-ribose) polymerase genes
    Patent number: 9051553
    Abstract: The invention relates to poly(ADP-ribose)polymerase (PARP) homologs which have an amino acid sequence which has a) a functional NAD binding domain and b) no zinc finger sequence motif of the general formula CX2CXmHX2C in which m is an integral value from 28 or 30, and the X radicals are, independently of one another, any amino acid; and the functional equivalents thereof; nucleic acids coding therefor; antibodies with specificity for the novel protein; pharmaceutical and gene therapy compositions which comprise products according to the invention; methods for the analytical determination of the proteins and nucleic acids according to the invention; methods for identifying effectors or binding partners of the proteins according to the invention; novel PARP effectors; and methods for determining the activity of such effectors.
    Type: Grant
    Filed: May 12, 2010
    Date of Patent: June 9, 2015
    Assignee: AbbVie Deutschland GmbH & Co. KG
    Inventors: Michael Kock, Thomas Höger, Burkhard Kröger, Bernd Otterbach, Wilfried Lubisch, Hans-Georg Lemaire
  • NOVEL POLY(ADP-RIBOSE) POLYMERASE GENES
    Publication number: 20110107444
    Abstract: The invention relates to poly(ADP-ribose)polymerase (PARP) homologs which have an amino acid sequence which has a) a functional NAD binding domain and b) no zinc finger sequence motif of the general formula CX2CXmHX2C in which m is an integral value from 28 or 30, and the X radicals are, independently of one another, any amino acid; and the functional equivalents thereof; nucleic acids coding therefor; antibodies with specificity for the novel protein; pharmaceutical and gene therapy compositions which comprise products according to the invention; methods for the analytical determination of the proteins and nucleic acids according to the invention; methods for identifying effectors or binding partners of the proteins according to the invention; novel PARP effectors; and methods for determining the activity of such effectors.
    Type: Application
    Filed: May 12, 2010
    Publication date: May 5, 2011
    Inventors: MICHAEL KOCK, THOMAS HÖGER, BURKHARD KRÖGER, BERND OTTERBACH, WILFRIED LUBISCH, HANS-GEORG LEMAIRE
  • Poly(ADP-ribose) polymerase-gene
    Patent number: 7754459
    Abstract: The invention relates to poly(ADP-ribose)polymerase (PARP) homologs which have an amino acid sequence which has a) a functional NAD+ binding domain and b) no zinc finger sequence motif of the general formula CX2CXmHX2C ?in which ?m is an integral value from 28 or 30, and the X radicals are, independently of one another, any amino acid; and the functional equivalents thereof; nucleic acids coding therefor; antibodies with specificity for the novel protein; pharmaceutical and gene therapy compositions which comprise products according to the invention; methods for the analytical determination of the proteins and nucleic acids according to the invention; methods for identifying effectors or binding partners of the proteins according to the invention; novel PARP effectors; and methods for determining the activity of such effectors.
    Type: Grant
    Filed: June 4, 1999
    Date of Patent: July 13, 2010
    Assignee: BASF Aktiengesellschaft
    Inventors: Michael Kock, Thomas Höger, Burkhard Kröger, Bernd Otterbach, Wilfried Lubisch, Hans-Georg Lemaire