Patents by Inventor Bernd Sauerbrei

Bernd Sauerbrei has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6958395
    Abstract: The present invention relates to a method by which saccharide compounds can be prepared in a very easy way. This method comprises the steps of: (a) attaching at least one saccharide to a cyclic or acyclic diene, (b) reacting the saccharide-containing diene obtained in step (a) or a commercially available saccharide-containing diene with a dienophile by Diels-Alder reaction.
    Type: Grant
    Filed: August 22, 2001
    Date of Patent: October 25, 2005
    Assignee: Deutsches Krebsforschungszentrum Stiftung des Offentlichen Rechts
    Inventors: Manfred Wiessler, Hans-Christian Kliem, Bernd Sauerbrei, Birgit Schmauser
  • Publication number: 20040059101
    Abstract: The present invention relates to a method by which saccharide compounds can be prepared in a very easy way.
    Type: Application
    Filed: September 8, 2003
    Publication date: March 25, 2004
    Inventors: Manfred Weissler, Hans-Christian Kliem, Bernd Sauerbrei, Birgit Schmauser
  • Patent number: 6271345
    Abstract: An enzyme cleavable linker is prepared on which organic compounds are synthesized when the linker is bound to a solid phase. The linker contains a functional group on which a synthesized organic compound is bound when synthesis takes place, and a recognition site for a hydrolytic enzyme. Reacting the linker with the enzyme causes the linker to fragment at a site different from the recognition site to liberate the synthesized organic compound. The solid phase may be a crosslinked polyacrylamide containing an amino group for attaching the linker, and the linker is bound to the solid phase via a spacer. The spacer is attached to the solid phase by an ester, ether, amide or amine linkage, or a sulfide or phosphate linkage. In a specific reaction of forming a solid phase containing the linker, 2-acetoxy-5-hydroxymethylbenzoic acid is attached to an amino group-containing polymer via a spacer followed by conversion to a chloroformic ester.
    Type: Grant
    Filed: December 28, 1998
    Date of Patent: August 7, 2001
    Assignee: BASF Aktiengesellschaft
    Inventors: Herbert Waldmann, Bernd Sauerbrei, Uwe Grether