Patents by Inventor Bernd Thumbeck

Bernd Thumbeck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190275122
    Abstract: Orally administrable pharmaceutical compositions of lipase-containing products, particularly pancreatin and pancreatin-containing products, or of enzyme products which contain at least one lipase of non-animal, especially microbial origin, which improve the lipolytic activity and particularly result in stabilization of the lipase in the acidic pH range. These oral pharmaceutical compositions contain a system which includes at least one surfactant and one co-surfactant and optionally a lipophilic phase, and are self-emulsifiable on contact with a hydrophilic and a lipophilic phase. The compositions according to the invention are suitable for treating or inhibiting maldigestion, especially maldigestion due to chronic exocrine pancreatic insufficiency, in mammals and humans.
    Type: Application
    Filed: May 23, 2019
    Publication date: September 12, 2019
    Inventors: George Shlieout, Bernd Boedecker, Siegfried Schaefer, Bernd Thumbeck, Peter-Colin Gregory
  • Publication number: 20140302000
    Abstract: Orally administrable pharmaceutical compositions of lipase-containing products, particularly pancreatin and pancreatin-containing products, or of enzyme products which contain at least one lipase of non-animal, especially microbial origin, which improve the lipolytic activity and particularly result in stabilization of the lipase in the acidic pH range. These oral pharmaceutical compositions contain a system which includes at least one surfactant and one co-surfactant and optionally a lipophilic phase, and are self-emulsifiable on contact with a hydrophilic and a lipophilic phase. The compositions according to the invention are suitable for treating or inhibiting maldigestion, especially maldigestion due to chronic exocrine pancreatic insufficiency, in mammals and humans.
    Type: Application
    Filed: June 18, 2014
    Publication date: October 9, 2014
    Inventors: George Shlieout, Bernd Boedecker, Siegfried Schaefer, Bernd Thumbeck, Peter-Colin Gregory
  • Patent number: 8802087
    Abstract: Orally administrable pharmaceutical compositions of lipase-containing products, particularly pancreatin and pancreatin-containing products, or of enzyme products which contain at least one lipase of non-animal, especially microbial origin, which improve the lipolytic activity and particularly result in stabilization of the lipase in the acidic pH range. These oral pharmaceutical compositions contain a system which includes at least one surfactant and one co-surfactant and optionally a lipophilic phase, and are self-emulsifiable on contact with a hydrophilic and a lipophilic phase. The compositions according to the invention are suitable for treating or inhibiting maldigestion, especially maldigestion due to chronic exocrine pancreatic insufficiency, in mammals and humans.
    Type: Grant
    Filed: March 22, 2005
    Date of Patent: August 12, 2014
    Assignee: Abbott Products GmbH
    Inventors: George Shlieout, Bernd Boedecker, Siegfried Schaefer, Bernd Thumbeck, Peter-Colin Gregory
  • Patent number: 8329679
    Abstract: A method of producing a pharmaceutical preformulation in the form of a solid, free-flowing dry extract of a natural mixture of conjugated equine estrogens, which is particularly suitable use in for solid galenic forms, e.g. tabletting. The conjugated estrogens are available for further galenic processing in a form which assures the chemical stability of the hormones and permits advantageous processing into solid galenic forms, for example a tablet.
    Type: Grant
    Filed: May 30, 2012
    Date of Patent: December 11, 2012
    Assignee: Abbott Products GmbH
    Inventors: Bernd Thumbeck, Ingo Bonnacker, Martina Lerch
  • Patent number: 8273728
    Abstract: A pharmaceutical preformulation in the form of a solid, free-flowing dry extract of a natural mixture of conjugated equine estrogens, which is particularly suitable use in for solid galenic forms, e.g. tabletting. The conjugated estrogens are available for further galenic processing in a form which assures the chemical stability of the hormones and permits advantageous processing into solid galenic forms, for example a tablet. The invention furthermore relates to a method for producing these preformulations in the form of a dry extract.
    Type: Grant
    Filed: June 14, 2004
    Date of Patent: September 25, 2012
    Assignee: Abbott Products GmbH
    Inventors: Bernd Thumbeck, Ingo Bonnacker, Martina Lerch
  • Publication number: 20120237666
    Abstract: A method of producing a pharmaceutical preformulation in the form of a solid, free-flowing dry extract of a natural mixture of conjugated equine estrogens, which is particularly suitable use in for solid galenic forms, e.g. tabletting. The conjugated estrogens are available for further galenic processing in a form which assures the chemical stability of the hormones and permits advantageous processing into solid galenic forms, for example a tablet.
    Type: Application
    Filed: May 30, 2012
    Publication date: September 20, 2012
    Applicant: Abbott Products GmbH
    Inventors: Bernd THUMBECK, Ingo BONNACKER, Martina LERCH
  • Patent number: 8268351
    Abstract: A pharmaceutical matrix film tablet with controlled release of natural mixtures of conjugated estrogens which have been obtained from the urine of pregnant mares.
    Type: Grant
    Filed: June 14, 2004
    Date of Patent: September 18, 2012
    Assignee: Abbott Products GmbH
    Inventors: Bernd Thumbeck, Klaus Budde, Gerhard Kristen, Margit Wiards
  • Patent number: 7479378
    Abstract: A method for analyzing the identity, protein and/or peptide pattern and also the stability of samples containing physiologically acceptable enzyme mixtures with lipolytic, proteolytic and amylolytic activity, particularly mixtures of digestive enzymes such as pancreatin, for use in manufacturing medicinal products comprising such enzyme mixtures, e.g. precipitated pancreatin or pancreatin mini-microspheres.
    Type: Grant
    Filed: July 29, 2004
    Date of Patent: January 20, 2009
    Assignee: Solvay Pharmaceuticals GmbH
    Inventors: Andreas Potthoff, Andreas Koerner, Bernd Thumbeck
  • Publication number: 20050250817
    Abstract: Orally administrable pharmaceutical compositions of lipase-containing products, particularly pancreatin and pancreatin-containing products, or of enzyme products which contain at least one lipase of non-animal, especially microbial origin, which improve the lipolytic activity and particularly result in stabilization of the lipase in the acidic pH range. These oral pharmaceutical compositions contain a system which includes at least one surfactant and one co-surfactant and optionally a lipophilic phase, and are self-emulsifiable on contact with a hydrophilic and a lipophilic phase. The compositions according to the invention are suitable for treating or inhibiting maldigestion, especially maldigestion due to chronic exocrine pancreatic insufficiency, in mammals and humans.
    Type: Application
    Filed: March 22, 2005
    Publication date: November 10, 2005
    Applicant: Solvay Pharmaceuticals GmbH
    Inventors: George Shlieout, Bernd Boedecker, Siegfried Schaefer, Bernd Thumbeck, Peter-Colin Gregory
  • Publication number: 20050112743
    Abstract: A method for analyzing the identity, protein and/or peptide pattern and also the stability of samples containing physiologically acceptable enzyme mixtures with lipolytic, proteolytic and amylolytic activity, particularly mixtures of digestive enzymes such as pancreatin, for use in manufacturing medicinal products comprising such enzyme mixtures, e.g. precipitated pancreatin or pancreatin mini-microspheres.
    Type: Application
    Filed: July 29, 2004
    Publication date: May 26, 2005
    Applicant: Solvay Pharmaceuticals GmbH
    Inventors: Andreas Potthoff, Andreas Koerner, Bernd Thumbeck
  • Publication number: 20050019408
    Abstract: A pharmaceutical matrix film tablet with controlled release of natural mixtures of conjugated estrogens which have been obtained from the urine of pregnant mares.
    Type: Application
    Filed: June 14, 2004
    Publication date: January 27, 2005
    Applicant: Solvay Pharmaceuticals GmbH
    Inventors: Bernd Thumbeck, Klaus Budde, Gerhard Kristen, Margit Wiards
  • Publication number: 20050009800
    Abstract: A pharmaceutical preformulation in the form of a solid, free-flowing dry extract of a natural mixture of conjugated equine estrogens, which is particularly suitable use in for solid galenic forms, e.g. tabletting. The conjugated estrogens are available for further galenic processing in a form which assures the chemical stability of the hormones and permits advantageous processing into solid galenic forms, for example a tablet. The invention furthermore relates to a method for producing these preformulations in the form of a dry extract.
    Type: Application
    Filed: June 14, 2004
    Publication date: January 13, 2005
    Applicant: Solvay Pharmaceuticals GmbH
    Inventors: Bernd Thumbeck, Ingo Bonnacker, Martina Lerch