Patents by Inventor Bernd-Ulrich Wilhelm

Bernd-Ulrich Wilhelm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11541353
    Abstract: The disclosure relates to a container for filtering a suspension which comprises a lid and a vessel. The container comprises a filter that divides an interior space of the container into a first compartment and a second compartment. The lid comprises a first access and a second access. The first access is connected to the first compartment, and the second access is connected to the second compartment.
    Type: Grant
    Filed: August 25, 2016
    Date of Patent: January 3, 2023
    Assignee: bbi-biotech GmbH
    Inventors: Bernd-Ulrich Wilhelm, Ulrike Klattkowsky, Jan Millauer
  • Publication number: 20210130763
    Abstract: The invention relates to a device for sampling from bioreactors, comprising a rising line (1) connectable to a bioreactor, a tap line (2), and a withdrawal line (3), which are connected to a T-like connection. The withdrawal line (3) comprises a first shut-off valve (4), the tap line (2) is connected to a positive pressure source (5), and the withdrawal line (3) is connected to a pump (7). In the device for sampling, the positive pressure source (5), the pump (7), and the first shut-off valve (4) are controllable in an automated manner via a control unit (13). The invention furthermore relates to a method for using such a device for sampling.
    Type: Application
    Filed: March 20, 2019
    Publication date: May 6, 2021
    Inventors: Bernd-Ulrich Wilhelm, Jan Millauer, Ronnie Wilhelm
  • Patent number: 10344254
    Abstract: Reactor plant and process for culturing phototropic microorganisms with a reactor vessel and a photosynthetic module, which are connected with one another in a circulation circuit by a pump and can be controlled via a control unit, where in the circulation circuit or in the reactor vessel, a homogenizer is provided, where a light-intensity control of the photosynthetic module is provided, and where a bypass of the circulation circuit or of the reactor vessel with a filter device which is arranged externally of the reactor vessel for separating off extracellular products during the fermentation is provided.
    Type: Grant
    Filed: March 6, 2007
    Date of Patent: July 9, 2019
    Assignee: Sartorius AG
    Inventors: Wolfgang Kahlert, Bernd-Ulrich Wilhelm, Wolf-Dietrich Linke
  • Publication number: 20180243695
    Abstract: The disclosure relates to a container for filtering a suspension which comprises a lid and a vessel. The container comprises a filter that divides an interior space of the container into a first compartment and a second compartment. The lid comprises a first access and a second access. The first access is connected to the first compartment, and the second access is connected to the second compartment.
    Type: Application
    Filed: August 25, 2016
    Publication date: August 30, 2018
    Inventors: Bernd-Ulrich Wilhelm, Ulrike Klattkowsky, Jan Millauer
  • Patent number: 8846383
    Abstract: Disclosed are a method and a device for the biotechnological production of valuable products, in which a medium is fed to a bioreactor and is subjected to a fermentation process, the valuable product is gathered as a filtered permeate and/or concentrated retentate via a cross-flow filtration system that is mounted downstream thereof, and residues are once again fed to the bioreactor until being gathered as a retentate. Other materials can be fed to the bioreactor in a controlled manner in addition to the medium while the concentrated retentate and permeate can be gathered in a controlled manner. The fermentation process and the filtration process are regulated in a synchronized manner in an integrated system via a digital control unit.
    Type: Grant
    Filed: June 21, 2003
    Date of Patent: September 30, 2014
    Assignee: Sartorius AG
    Inventors: Reiner Luttmann, Wilfried Kappel, Toralf Gliem, Mohammad Saeed Ajam, Lars Boettcher, Bernd-Ulrich Wilhelm, Wolfgang Rietschel
  • Patent number: 7425441
    Abstract: A bioreactor for culturing microorganisms which has a reactor vessel, a plurality of gas-introduction tubes and a gas-introduction system for introducing gas into a culture medium in the gas-introduction tubes via injectors, wherein the gas-introduction tubes are connected by their respective lower end, in the vertical direction, to the reactor vessel and by their opposite upper end to the upper end of an upright vessel which is likewise connected by its lower end to the reactor vessel, and at the upper end of the upright vessel an expansion vessel is arranged.
    Type: Grant
    Filed: April 11, 2005
    Date of Patent: September 16, 2008
    Assignee: Sartorius Stedim Biotech GmbH
    Inventors: Jürgen Broneske, Horst Franke, Otto Pulz, Heinz-Rüdiger Keitel, Wolf-Dietrich Linke, Bernd-Ulrich Wilhelm, Rainer Salzmann, Wolfgang Kröger, Mirko Riese
  • Patent number: 7320889
    Abstract: A device and a method for the cultivation of cells is disclosed that utilizes external pneumatic pressure responsive to liquid level sensors to gently recirculate and cause turbulence in cell growth medium to promote cell growth without any shearing action and without a stir motor or mechanical manipulation means.
    Type: Grant
    Filed: May 7, 2004
    Date of Patent: January 22, 2008
    Assignee: Sartorius Stedim Biotech GmbH
    Inventors: Wolfgang Kahlert, Bernd-Ulrich Wilhelm, Rainer Salzmann, Wolfgang Rietschel
  • Publication number: 20070231886
    Abstract: Reactor plant and process for culturing phototropic microorganisms with a reactor vessel and a photosynthetic module, which are connected with one another in a circulation circuit by a pump and can be controlled via a control unit, where in the circulation circuit or in the reactor vessel, a homogenizer is provided, where a light-intensity control of the photo-synthetic module is provided, and where a bypass of the circulation circuit or of the reactor vessel with a filter device which is arranged externally of the reactor vessel for separating off extracellular products during the fermentation is provided.
    Type: Application
    Filed: March 6, 2007
    Publication date: October 4, 2007
    Applicant: Sartorius AG
    Inventors: Wolfgang Kahlert, Bernd-Ulrich Wilhelm, Wolf-Dietrich Linke
  • Publication number: 20060014239
    Abstract: Disclosed are a method and a device for the biotechnological production of valuable products, in which a medium is fed to a bioreactor and is subjected to a fermentation process, the valuable product is gathered as a filtered permeate and/or concentrated retentate via a cross-flow filtration system that is mounted downstream thereof, and residues are once again fed to the bioreactor until being gathered as a retentate. Other materials can be fed to the bioreactor in a controlled manner in addition to the medium while the concentrated retentate and permeate can be gathered in a controlled manner. The fermentation process and the filtration process are regulated in a synchronized manner in an integrated system via a digital control unit.
    Type: Application
    Filed: June 21, 2003
    Publication date: January 19, 2006
    Inventors: Reiner Luttmann, Wilfried Kappel, Toralf Gliem, Mohammad Ajam, Lars Boettcher, Bernd-Ulrich Wilhelm, Wolfgang Rietschel
  • Publication number: 20050255584
    Abstract: A bioreactor for culturing microorganisms which has a reactor vessel, a plurality of gas-introduction tubes and a gas-introduction system for introducing gas into a culture medium in the gas-introduction tubes via injectors, wherein the gas-introduction tubes are connected by their respective lower end, in the vertical direction, to the reactor vessel and by their opposite upper end to the upper end of an upright vessel which is likewise connected by its lower end to the reactor vessel, and at the upper end of the upright vessel an expansion vessel is arranged.
    Type: Application
    Filed: April 11, 2005
    Publication date: November 17, 2005
    Applicant: Sartorius AG
    Inventors: Jurgen Broneske, Horst Franke, Otto Pulz, Heinz-Rudiger Keitel, Wolf-Dietrich Linke, Bernd-Ulrich Wilhelm, Rainer Salzmann, Wolfgang Kroger, Mirko Riese
  • Publication number: 20040229348
    Abstract: A device and a method for the cultivation of cells is disclosed that utilizes external pneumatic pressure responsive to liquid level sensors to gently recirculate and cause turbulence in cell growth medium to promote cell growth without any shearing action and without a stir motor or mechanical manipulation means.
    Type: Application
    Filed: May 7, 2004
    Publication date: November 18, 2004
    Inventors: Wolfgang Kahlert, Bernd-Ulrich Wilhelm, Rainer Salzmann, Wolfgang Rietschel