Patents by Inventor Bernd Zierenberg

Bernd Zierenberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7699052
    Abstract: The present invention relates to a propellant-gas-free apparatus for the dispensing of liquids, a container cartridge suitable for this for storing the liquid and the ensemble comprising both. The invention comprises a device for the exertion of pressure and for accommodating a container cartridge and a container cartridge in which the dispensing facility is integrated.
    Type: Grant
    Filed: August 26, 2003
    Date of Patent: April 20, 2010
    Assignee: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Joerg Schiewe, Gilbert Wuttke, Bernd Zierenberg, Stephen Dunne, Horst Wergen
  • Patent number: 7665461
    Abstract: A nebulizer for a fluid and a container holding the fluid which is insertable in the nebulizer are proposed. To improve safety in use it is proposed that the nebulizer comprises first coding means and the container is associated with second coding means, so that the container can only be inserted in the nebulizer or used therewith if the codes match. Preferably, the code associated with the container comprises clear identification of the fluid contained in the container.
    Type: Grant
    Filed: February 24, 2005
    Date of Patent: February 23, 2010
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Bernd Zierenberg, Gilbert Wuttke, Michael Schyra, Guido Schmiedel, Hubert Kunze, Matthias Hausmann, Christian Golberg, Johannes Geser, Andreas Fiol
  • Publication number: 20090188495
    Abstract: The invention discloses a pre-metered dry powder inhaler for use in treatment of respiratory disorders. The inhaler comprises a foil cutter arranged for opening a dry, moisture-tight seal formed by a dose container with tiotropium particles and a seal foil fixed to the container. The tiotropium-containing dose protected from moisture ingress by the moisture-tight barrier seal is loaded in the container using volumetric or electric field dose forming techniques.
    Type: Application
    Filed: April 3, 2009
    Publication date: July 30, 2009
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Thomas NILSSON, Mattias MYRMAN, Sven CALANDER, Alf NIEMI, Bernd ZIERENBERG, Holger MEMMESHEIMER, Christine LUKENHEIMER
  • Publication number: 20090188496
    Abstract: A medical product suitable for storing and delivering a pre-metered dose of tiotropium, devices containing the same, and methods of using the same.
    Type: Application
    Filed: April 3, 2009
    Publication date: July 30, 2009
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Thomas NILSSON, Mattias MYRMAN, Sven CALANDER, Alf NIEMI, Bernd ZIERENBERG, Holger MEMMESHEIMER, Christine LUNKENHEIMER
  • Publication number: 20090188497
    Abstract: The invention discloses a medical product that may be used in a treatment of respiratory disorders.
    Type: Application
    Filed: April 3, 2009
    Publication date: July 30, 2009
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Thomas NILSSON, Mattias MYRMAN, Sven CALANDER, Alf NIEMI, Bernd ZIERENBERG, Holger MEMMESHEIMER, Christine LUNKENHEIMER
  • Publication number: 20090192185
    Abstract: The invention discloses a medical product for use in a treatment of respiratory disorders, and comprises a metered dose of a tiotropium dry powder formulation, directly loaded and sealed into a container made to act as a dry high barrier seal to prevent the capture and ingress of moisture into the tiotropium powder. The dose of tiotropium is further adapted for inhalation and the container is so tight that the efficacy of the dose when delivered is unaffected by moisture. In a further aspect of the invention a type of inhaler is illustrated, which may accept at least one sealed, moisture-tight container of a dose of tiotropium, to deliver the dose with a consistent fine particle dose, over the expected shelf life of the product.
    Type: Application
    Filed: April 3, 2009
    Publication date: July 30, 2009
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Thomas NILSSON, Mattias MYRMAN, Sven CALANDER, Alf NIEMI, Bernd ZIERENBERG, Holger MEMMESHEIMER, Christine LUNKENHEIMER
  • Publication number: 20090185983
    Abstract: The present invention relates to pharmaceutical preparations in the form of aqueous solutions for the production of propellant-free aerosols.
    Type: Application
    Filed: March 30, 2009
    Publication date: July 23, 2009
    Applicant: Boehringer Ingelheim Pharma KG
    Inventors: Bernhard Freund, Bernd Zierenberg
  • Publication number: 20090099225
    Abstract: The present invention relates to pharmaceutical preparations in the form of aqueous solutions for the production of propellant-free aerosols.
    Type: Application
    Filed: December 18, 2008
    Publication date: April 16, 2009
    Applicant: Boehringer Ingelheim Pharma KG
    Inventors: Bernhard Freund, Bernd Zierenberg
  • Publication number: 20090068275
    Abstract: The invention relates to an improved process for the production of powders of an inhalable medicament by crystallization from a supersaturated fluid containing said medicament, the method comprising passing along a tubular reactor (a) a segmented flow of that fluid comprised of discrete volumes; or (b) a fluid mixture being separated by discrete volumes of a separating fluid which is substantially immiscible with said fluid, characterized in that the crystallization is initiated by application of ultrasound
    Type: Application
    Filed: November 3, 2008
    Publication date: March 12, 2009
    Applicants: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE, Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Nathalie JONGEN, Jacques LEMAITRE, Paul BOWEN, Marcel DONNET, Joerg SCHIEWE, Bernd ZIERENBERG
  • Publication number: 20090025719
    Abstract: The invention discloses a dry powder inhaler for use in a treatment of respiratory disorders.
    Type: Application
    Filed: June 8, 2006
    Publication date: January 29, 2009
    Inventors: Bernd Zierenberg, Holger Memmesheimer, Christine Lunkenheimer, Sven Calander, Alf Niemi, Thomas Nilsson, Mattias Myrman
  • Patent number: 7470422
    Abstract: The present invention relates to pharmaceutical preparations in the form of aqueous solutions for the production of propellant-free aerosols.
    Type: Grant
    Filed: August 17, 2006
    Date of Patent: December 30, 2008
    Assignee: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Bernhard Freund, Bernd Zierenberg
  • Publication number: 20080308103
    Abstract: The subject matter of the invention is a capsule, in particular for the packaging of inhalation formulations, in which at least one cavity is enclosed by a wall, characterized in that at least one portion of the wall has a polymer composition that contains at least one adsorbent, as well as said capsule's preferred use. Furthermore an inhaler and secondary packaging containing at least one such capsule are also described.
    Type: Application
    Filed: May 17, 2006
    Publication date: December 18, 2008
    Applicants: AIRSEC S.A.S., BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG
    Inventors: Didier Lancesseur, Dieter Hochrainer, Jorg Schiewe, Bernd Zierenberg
  • Publication number: 20080236579
    Abstract: An inhalation kit comprising: (a) an inhaler displaying a flow resistance of about 0.01 to 0.1, ?{square root over (kPa)} min/L; and (b) an inhalable powder comprising tiotropium in admixture with a physiologically acceptable excipient with an average particle size of between 10 to 500 ?m, and a method of administering an inhalable powder containing tiotropium in admixture with a physiologically acceptable excipient with an average particle size of between 10 pm to 500 ?m, the method comprising actuating an inhaler a flow resistance of about 0.01 to 0.1 ?{square root over (kPa)} min/L containing the inhalable powder.
    Type: Application
    Filed: March 24, 2008
    Publication date: October 2, 2008
    Inventors: Bernd Zierenberg, Christine Lunkenheimer, Holger Memmesheimer
  • Publication number: 20080132493
    Abstract: Aqueous cyclodextrin-free solution of meloxicam suitable for administration by needleless injection, containing a pharmacologically acceptable meloxicam salt of an organic or inorganic base and one or more suitable excipients, the content of dissolved meloxicam salt being from 35 to 100 mg/ml. The formulation according to the invention has a shelf-life of up to 24 months or more.
    Type: Application
    Filed: August 27, 2007
    Publication date: June 5, 2008
    Inventors: Martin Andreas Folger, Stefan Henke, Bernhard Hassel, Bernd Zierenberg
  • Publication number: 20080102037
    Abstract: The invention relates to ethanol-containing pharmaceutical preparations for the production of propellant-free aerosols.
    Type: Application
    Filed: January 3, 2008
    Publication date: May 1, 2008
    Inventors: Bernhard FREUND, Michael Krueger, Bernd Zierenberg
  • Publication number: 20080097359
    Abstract: The present invention relates to atomizers for administering liquids to the cornea or conjunctiva of the eye, special eye adapters for atomizers and the use of atomizers for opthalmological administration. The atomizers according to the invention are free from propellant gas and have an energy reservoir for supplying the energy needed for the atomization process.
    Type: Application
    Filed: December 18, 2007
    Publication date: April 24, 2008
    Inventors: Dieter Hochrainer, Bernd Zierenberg, Michael Diestelhorst, Isolde Martin
  • Patent number: 7314187
    Abstract: Atomizers for administering liquids to the cornea or conjunctiva of the eye, special eye adapters for atomizers and the use of atomizers for ophthalmological administration. The atomizers are free from propellant gas and have an energy reservoir for supplying the energy needed for the atomization process.
    Type: Grant
    Filed: July 14, 2006
    Date of Patent: January 1, 2008
    Assignee: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Dieter Hochrainer, Bernd Zierenberg, Michael Diestelhorst, Isolde Martin
  • Patent number: 7249599
    Abstract: A method for crystallizing a substance, especially an inhalable medicament, comprising the following steps: (a) dissolving said substance in a solvent, to produce a solution of said substance, (b) producing a segmented stream which consists of alternating segments of said solution of the substance and of a transport medium, (c) introducing said segmented stream into the first end of a retention stretch, which retention stretch has a first end and a second end, so that said segmented stream passes from said first end to said second end of said retention stretch, and exists from the second end of the retention stretch, (d) cooling the retention stretch, to thereby bring about crystallization of the substance in the segments of solution, in the segmented stream, as said segmented stream passes through the retention stretch, and (e) separating the crystals of material from the segmented stream as it exits from the second end of the retention stretch.
    Type: Grant
    Filed: June 30, 2005
    Date of Patent: July 31, 2007
    Assignee: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Joerg Schiewe, Bernd Zierenberg
  • Publication number: 20070110678
    Abstract: A method for administration and preparation of pharmaceutical dry powder doses are disclosed. The metered dry powder doses are formed from a finely divided dry powder of an selected anticholinergic agent to be used in a dry powder inhaler device. The metered dry powder medicinal dose is arranged as a medicinally effective quantity of the selected medicament onto a dose bed and moisture-tight sealed by using a high barrier seal, for introduction into an inhaler device provided with an Air-razor device for obtaining a fine particle fraction, FPF, of at least 30-50% of delivered powder mass when suction through the inhaler is applied, whereby the dose is delivered to and deposited in the lung of the user during a single inhalation effort.
    Type: Application
    Filed: June 8, 2006
    Publication date: May 17, 2007
    Inventors: Bernd Zierenberg, Holger Memmesheimer, Christine Lunkenheimer, Sven Calander, Alf Niemi, Thomas Nilsson, Mattias Myrman
  • Publication number: 20070104655
    Abstract: A medical product suitable for storing and delivering a pre-metered dose of tiotropium, devices containing the same, and methods of using the same.
    Type: Application
    Filed: June 8, 2006
    Publication date: May 10, 2007
    Inventors: Bernd Zierenberg, Holger Memmesheimer, Christine Lunkenheimer, Sven Calander, Alf Niemi, Thomas Nilsson, Mattias Myrman