Abstract: A method for checking the integrity of functional units that are reloadable during runtime of an electronic component in a dynamically reconfigurable region of the electronic component, wherein the electronic component, which is formed as a programmable logic circuit, has, in addition to a static region, a dynamically reconfigurable region and the reloadable functional units have predefined interfaces, where an associated twin functional unit is configured in a specified subregion of the dynamically reconfigurable region for each reloadable functional unit, a reloadable functional unit is loaded into a specified subregion of the dynamically reconfigurable region, supplied with identical input data to the associated twin functional unit, and executed in parallel with the twin functional unit, and where output data of the reloaded functional unit and associated twin functional unit are compared and the reloaded functional unit is enabled if a match between the two output data is found.

Abstract: A peptide is described, which consists of 7-17 adjacent amino acids and comprises the hexamer TXEXXE, wherein X, X and X can be any natural or non-natural amino acid, wherein the peptide has no TNF receptor binding activity and is cyclized, for the prevention and treatment of hyperpermeability of epithelial cells and endothelial cells.

Abstract: A method for managing licenses for soft IP on a partially reconfigurable hardware system, in particular an FPGA, wherein a license manager is provided in the non-configurable part of the hardware system, or is accessible only for the non-configurable part of the hardware system, where the license manager has exclusive access to a non-volatile memory in which license data having a time restriction of the useful life of at least one soft IP is stored, where before activating a particular soft IP, the license manager checks whether the useful life has expired, where the license manager only releases use of the soft IP if the useful life has not yet expired, where the license data is changed using a key, which is stored in a non-volatile memory for license data, and where a new key is stored and the preceding key is deleted when the license data is changed.

Abstract: A system and method for the predictive maintenance of electronic components that includes sensors at at least one position via which present values of system parameters, such as temperature and voltage, and a signal propagation time at the at least one position are determined, where values of the system parameters and the signal propagation time presently determined by the sensors are retrieved by a central monitoring unit, an individual valid limit value is determined for the signal propagation time at each of the at least one position via the central monitoring unit based on the presently determined values of the system parameters, and the presently determined signal propagation time at each of the at least one position is compared with the associated valid limit value, and a notification is sent to a superordinate level, if the signal propagation time exceeds the limit value to trigger replacement of the electronic component.

Abstract: In one embodiment, an agricultural sampling apparatus is provided. The apparatus comprising: a wave emitter; a wave transmitter configured to direct the waves from the wave emitter as a plurality of linewise waves to irradiate surface points of the agricultural sample; a dispersive element configured to receive waves arriving from the sample and deflect the arriving waves in at least two directions depending upon the wavelength of an arriving wave; and a detector configured with a plurality of detection elements disposed in at least two dimensions, the detector configured to convert the waves arriving from the dispersive element to a signal.

Abstract: Described is a composition comprising a peptide which consists of 7-17 adjacent amino acids and comprises the hexamer TX1EX2X3E, where X1, X2, and X3 can be any natural or non-natural amino acid, and the peptide is cyclized and does not exhibit TNF receptor binding activity, and an inhibitor of viral neuraminidase.

Abstract: A method for managing licenses for soft IP on a partially reconfigurable hardware system, in particular an FPGA, wherein a license manager is provided in the non-configurable part of the hardware system, or is accessible only for the non-configurable part of the hardware system, where the license manager has exclusive access to a non-volatile memory in which license data having a time restriction of the useful life of at least one soft IP is stored, where before activating a particular soft IP, the license manager checks whether the useful life has expired, where the license manager only releases use of the soft IP if the useful life has not yet expired, where the license data is changed using a key, which is stored in a non-volatile memory for license data, and where a new key is stored and the preceding key is deleted when the license data is changed.

Abstract: Disclosed is a dry-powder peptide medicament with a non-typical concentration of carbohydrate excipient, as well as said medicament for use in treatment or prevention of a disease or condition, as well as methods for manufacturing said medicament.

Abstract: A refrigeration machine, in particular a cryopump for generating a vacuum, having a compressor for compressing a refrigerant substantially comprising helium and oil. Together with the compressor, an oil separator is arranged downstream in the delivery direction of the coolant. Furthermore, a cooling device in which the refrigeration medium expands. In order to adsorb harmful gases, an adsorption device is arranged upstream of the cooling device in the delivery direction.

Abstract: A method of conditioning/improving lung functions extracorporeally by treatment of a non-ischemic donor lung ex vivo with a cyclized compound of the amino acid sequence of formula X1-GQRETPEGAEAKPWY-X2 wherein X1 comprises an amino acid (sequence) with 1 to 4 members, comprising natural or unnatural amino acids, and X2 comprises one amino acid, selected from natural amino acids; and a pharmaceutical composition, comprising a peptide of formula I as defined in any one of claims 1 to 7, in a form, which is appropriate for spraying to obtain an aerosol for inhalation, or which is appropriate for the preparation of a spray to obtain an aerosol upon spraying, which is appropriate for inhalation.

Abstract: Described is a composition comprising a peptide which consists of 7-17 adjacent amino acids and comprises the hexamer TX1EX2X3E, where X1, X2, and X3 can be any natural or non-natural amino acid, and the peptide is cyclized and does not exhibit TNF receptor binding activity, and an inhibitor of viral neuraminidase.

Abstract: Cyclic peptide of formula I X1-GQRETPEGAEAKPWY-X2, wherein X1 comprises an amino acid (sequence), with 1 to 4 members, comprising natural and unnatural amino acids, and X2 comprises a natural amino acid, and wherein X1 comprises the N-terminal amino acid left in position 1, and X2 the C-terminal amino acid in the ultimate, right position, in the form of a lyophilisate without additives and/or stabilizers and its use.

Abstract: A system and method for the predictive maintenance of electronic components that includes sensors at at least one position via which present values of system parameters, such as temperature and voltage, and a signal propagation time at the at least one position are determined, where values of the system parameters and the signal propagation time presently determined by the sensors are retrieved by a central monitoring unit, an individual valid limit value is determined for the signal propagation time at each of the at least one position via the central monitoring unit based on the presently determined values of the system parameters, and the presently determined signal propagation time at each of the at least one position is compared with the associated valid limit value, and a notification is sent to a superordinate level, if the signal propagation time exceeds the limit value to trigger replacement of the electronic component.

Abstract: A calibration device for a calibration, in particular wet calibration of an extrusion device is provided. The calibration device comprises a calibrating element which includes an opening for guiding through a profile produced by means of an extrusion die of the extrusion device and at least one rotatable guide roller which is in contact with the profile when the profile is guided through the opening. The calibration device further comprises at least one separate bearing element insertable into a cutout of the calibrating element, via which the guide roller can rotatably be mounted on the calibrating element.

Abstract: A cyclic polypeptide comprising at least six contiguous amino acids from the amino acid sequence SEQ ID NO:1 Gly-Gln-Arg-Glu-Thr-Pro-Glu-Gly-Ala-Glu-Ala-Lys-Pro-Trp-Tyr for the treatment of autosomal recessive pseudohypoaldosteronism type 1 (PHA type1B) or for the restoration of the Na transport capacity of mutated loss-of-function ENaC.

Abstract: Described is a composition comprising a peptide which consists of 7-17 adjacent amino acids and comprises the hexamer TX1EX2X3E, where X1, X2, and X3 can be any natural or non-natural amino acid, and the peptide is cyclized and does not exhibit TNF receptor binding activity, and an inhibitor of viral neuraminidase.

Abstract: The present invention provides a method of treating and preventing altitude sickness, comprising the steps of: obtaining a peptide, wherein the peptide is 7-20 adjacent amino acids in length and comprises an amino acid sequence having a hexamer TX1EX2X3E, wherein X1, X2 and X3 can be any natural or unnatural amino acid, and wherein the peptide does not have tumor necrosis factor receptor binding activity, and wherein the peptide is cyclized; and administering to a patient having the pulmonary form of altitude sickness or being at risk of developing the pulmonary form of altitude sickness an effective amount of the peptide.

Abstract: Described is a composition comprising—a peptide which consists of 7-17 adjacent amino acids and comprises the hexamer TX1EX2X3E, where X1, X2 and X3 can be any natural or non-natural amino acid, and the peptide is cyclized and does not exhibit TNF receptor binding activity, and—an inhibitor of viral neuraminidase.

Abstract: A method for determining system reliability of a logic circuit, wherein a functional component model for design/simulation of a circuit model of the logic circuit is created, where functional components model are expanded by adding an associated power model, a temperature model, and a reliability, where the logic circuit is constructed with expanded model components and, based on simulation of the logic circuit aided by the constructed circuit model, a functional, a power-dependent, and a temperature-dependent behavior and a temperature-dependent failure rate are derived for each component in a component specific manner for a specified application case, and where in addition to the functional behavior, a power and temperature behavior and a total failure rate can be determined simply and dynamically, based on the derived data and dependent on temperature and simulation time for the logic circuit for the specified application case.

Abstract: In one embodiment, an agricultural sampling apparatus is provided. The apparatus comprising: a wave emitter; a wave transmitter configured to direct the waves from the wave emitter as a plurality of linewise waves to irradiate surface points of the agricultural sample; a dispersive element configured to receive waves arriving from the sample and deflect the arriving waves in at least two directions depending upon the wavelength of an arriving wave; and a detector configured with a plurality of detection elements disposed in at least two dimensions, the detector configured to convert the waves arriving from the dispersive element to a signal.