Patents by Inventor Bernhard B Singer

Bernhard B Singer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • A NOVEL ANTIBODY BINDING SPECIFICALLY TO HUMAN CEACAM1/3/5 AND USE THEREOF
    Publication number: 20230295338
    Abstract: The present invention is directed to an isolated antibody or antigen binding fragment thereof that binds within huCEA-CAMl/3/5 specifically to the amino acid epitope sequence PQQLFGYSWY (SEQ ID NO: 11), wherein the isolated antibody or antigen binding fragment preferably comprises three heavy chain complementarity determining regions (HCDR1, HCDR2, and HCDR3), and three light chain complementarity determining regions (LCDR1, LCDR2, and LCDR3), wherein HCDR1 comprises the amino acid sequence of SEQ ID NO:1; HCDR2 comprises the amino acid sequence of SEQ ID NO:2; and HCDR3 comprises the amino acid sequence of SEQ ID NO:3; and wherein LCDR1 comprises the amino acid sequence of SEQ ID NO:4; LCDR2 comprises the amino acid sequence of GAT or GATX as in SEQ ID NO:5; and LCDR3 comprises the amino acid sequence of SEQ ID NO:6.
    Type: Application
    Filed: May 10, 2021
    Publication date: September 21, 2023
    Inventor: Bernhard B. Singer
  • Agents and Methods for the Prevention or Treatment of H. Pylori Infections
    Publication number: 20230087805
    Abstract: The present invention relates to inhibitors of the interaction between H. pylori HopQ and a member of the carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family as well as to immunogenic compositions based on H. pylori HopQ. The present invention further relates to the use of the inhibitors and immunogenic compositions for preventing or treating a disease or disorder caused by or associated with H. pylori.
    Type: Application
    Filed: September 21, 2022
    Publication date: March 23, 2023
    Applicants: TECHNISCHE UNIVERSITÄT MÜNCHEN, MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V.
    Inventors: Anahita JAVAHERI, Tobias KRUSE, Markus GERHARD, Bernhard B. SINGER, Daniel HORNBURG, Han REMAUT, Matthias MANN, Felix MEISSNER, Steffen BACKERT
  • Methods for treatment of infections
    Patent number: 11471532
    Abstract: The present invention relates to inhibitors of the interaction between H. pylori IIopQ and a member of the carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family as well as to immunogenic compositions based on H. pylori HopQ. The present invention further relates to the use of the inhibitors and immunogenic compositions for preventing or treating a disease or disorder caused by or associated with H. pylori.
    Type: Grant
    Filed: July 20, 2017
    Date of Patent: October 18, 2022
    Assignees: MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG, DER WISSENSCHAFT EN E.V., TECHNISCHE UNIVERSITÄT MÜNCHEN
    Inventors: Anahita Javaheri, Tobias Kruse, Markus Gerhard, Bernhard B. Singer, Daniel Hornburg, Han Remaut, Matthias Mann, Felix Meissner, Steffen Backert
  • Agents and Methods for the Prevention or Treatment of H. Pylori Infections
    Publication number: 20210008207
    Abstract: The present invention relates to inhibitors of the interaction between H. pylori IIopQ and a member of the carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family as well as to immunogenic compositions based on H. pylori HopQ. The present invention further relates to the use of the inhibitors and immunogenic compositions for preventing or treating a disease or disorder caused by or associated with H. pylori.
    Type: Application
    Filed: July 20, 2017
    Publication date: January 14, 2021
    Applicants: TECHNISCHE UNIVERSITÄT MÜNCHEN, MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V.
    Inventors: Anahita JAVAHERI, Tobias KRUSE, Markus GERHARD, Bernhard B. SINGER, Daniel HORNBURG, Han REMAUT, Matthias MANN, Felix MEISSNER, Steffen BACKERT
  • Use of anti-ceacam antibodies for stimulating b cells in the production of monoclonal antibodies or in immunotheraphy
    Publication number: 20040005321
    Abstract: The present invention relates to a method and kit for the production of monoclonal anitbodies using B cell stimulatory agent(s), such as antiCEACAM antibody and LPS. Furthermore, the invention relates to use of CEACAM for B cell stimulation in for example immunotherapy.
    Type: Application
    Filed: June 25, 2003
    Publication date: January 8, 2004
    Inventors: Bernhard B Singer, Gediminas Greicius