Patents by Inventor Bernhard C. Prager

Bernhard C. Prager has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the production of 7-ACA derivatives
    Patent number: 5580978
    Abstract: The invention provides an improved process for the production of 7-amino-3-alkoxymethlycephem-4-carboxyl acid derivatives.
    Type: Grant
    Filed: April 13, 1995
    Date of Patent: December 3, 1996
    Assignee: Biochemie Gesellschaft m.b.H.
    Inventors: Bernhard C. Prager, Hubert Sturm
  • Stable, crystalline form of a cephalosporin intermediate product
    Patent number: 5182383
    Abstract: The invention relates to new stable, crystalline forms of the t-butylester of ceftazidime of formula ##STR1## and the production thereof.
    Type: Grant
    Filed: February 23, 1990
    Date of Patent: January 26, 1993
    Assignee: Biochemie Gesellschaft m.b.H.
    Inventors: Bernhard C. Prager, Karl Wessely, Werner Veit
  • Crystalline cephalosporin derivative
    Patent number: 5066798
    Abstract: The invention provides crystallilne (6R, 7R)-7-[[2 ( 2-Amino-4-thiazolyl)-(Z)-2-(1-diphenylmethoxycarbonyl-1-methylethoxy)imino ]acetamido]-3-(1--pyridiniummethyl)-3-cephem-4-carboxylate and a process for its production.
    Type: Grant
    Filed: June 15, 1990
    Date of Patent: November 19, 1991
    Assignee: Biochemie Gesellschaft m.b.H.
    Inventor: Bernhard C. Prager
  • Process for the production of cephalosporin derivatives
    Patent number: 4954624
    Abstract: New process for the production of the pentahydrate of ceftazidime of formula ##STR1## characterized in that the ester group of the compound of formula ##STR2## or an acid addition salt thereof, is cleaved by the sole use of aqueous hydrochloric acid, and the resulting ceftazidime is either crystallized directly from the reaction mixture as the pentahydrate by adding a base, or first of all the dihydrochloride of the ceftazidime is isolated by adding acetone and/or ethanol or another anti-solvent which is miscible with water, and this is converted into the pentahydrate by known methods.
    Type: Grant
    Filed: June 29, 1989
    Date of Patent: September 4, 1990
    Assignee: Sandoz Ltd.
    Inventor: Bernhard C. Prager
  • Method for preparing crystalline cephalosporin derivative
    Patent number: 4826972
    Abstract: The invention provides crystalline (6R, 7R)-7-[[2-(2-Amino-4-thiazolyl)-(Z)-2-(1-diphenylmethoxycarbonyl-1-methyle thoxy)imino ]acetamido]-3-(1-pyridiniummethyl)-3-cephem-4-carboxylate and a process for its production.
    Type: Grant
    Filed: June 3, 1987
    Date of Patent: May 2, 1989
    Assignee: BIOCHEMIE Gesellschaft m.b.H.
    Inventor: Bernhard C. Prager
  • Deacylation of amides
    Patent number: 4562253
    Abstract: De-acylation of Penicillins and Cephalosporins to obtain the corresponding 6-aminopenicillanic acid or 7-aminocephalosporanic acid by the imino halide/imino ether process using long chain bases.
    Type: Grant
    Filed: August 3, 1983
    Date of Patent: December 31, 1985
    Assignee: Biochemie Gesellschaft m.b.H.
    Inventors: Bernhard C. Prager, Peter Punk, Heinrich Thaler