Abstract: The invention relates to an apparatus 10 for storing and/or processing at least one medium 11, in particular a bioprocessing device, comprising at least one disposable container 1, which is designed to accommodate at least some of the at least one medium 11, and at least one overpressure protection means 5, which is fluid-connected to the at least one disposable container 1. The at least one overpressure protection means is designed, when triggered, to conduct at least some of the at least one medium 11 into an apparatus region 3a? in front of the overpressure protection means 5 in relation to a flow direction F, in particular into the at least one disposable container 1 and/or into at least one further, second container 1a.

Abstract: A single-use filtration device including a plurality of single-use filter capsules connected with each other by rigid lines, of which at least a part is firmly mounted in a raster universally specified by a holder. The filter capsules, in particular as regards the type of filter, type of construction and/or size, and/or the connections of the filter capsules, are preconfigured for a desired filtration process.

Abstract: A method of filtering a large volume of a medium using a pre-sterilizable, at least partially automated single-use filtration device which includes an unfiltrate inlet, a filtrate outlet, a main line running between the unfiltrate inlet and the filtrate outlet, filter elements arranged in the main line, a venting line and sensors for detecting specific process parameters and regulating means for adjusting specific process parameters, wherein the sensors and regulating means are connected to an external monitoring and control system which is adapted for evaluating and processing sensor data and for piloting the regulating means based on one or more control algorithms, comprises the following process steps: a) filling the single-use filtration device with medium with low flow; b) venting the single-use filtration device through the venting line; c) closing the venting line; d) rinsing the single-use filtration device, in particular the filter elements; e) filtering the medium by means of the filter elements; f)

Abstract: A bioprocessing installation comprising a reservoir tank, one or more fluid lines, one or more receiving containers and an electronic control unit. The fluid line fluidically connects the reservoir tank to a receiving container. The liquid biological medium can be transferred from the reservoir tank through the fluid line into the at least one receiving container. The bioprocessing installation comprises a sensor arrangement with at least one gas bubble sensor, which sensor arrangement is configured to detect one or more gas bubbles or foam or separated phases in the liquid biological medium by a gas bubble sensor and to generate one or more corresponding sensor signals, and the electronic control unit is configured to monitor the transfer of the liquid biological medium from the reservoir tank in the direction of the at least one receiving container based on the sensor signals generated by the sensor arrangement.

Abstract: An automated single-use filtration device, in particular for large-volume filtration processes, comprises an unfiltrate inlet, one or more filter elements, a filtrate outlet and sensors for detecting specific process parameters and regulating mechanisms for adjusting specific process parameters. The sensors and regulating mechanisms are connected to an external monitoring and control system, which is adapted for evaluating and processing sensor data and for piloting the regulating mechanisms based on one or more control algorithms.

Abstract: The invention relates to a bioprocessing system having a main line (2) for conduction of a main flow (3) of a liquid, in particular biological, medium (45), having a main flow pump (5) for generation of the main flow (3) and having a system part (46) connected to the main line (2).

Abstract: The invention relates to an apparatus 10 for storing and/or processing at least one medium 11, in particular a bioprocessing device, comprising at least one disposable container 1, which is designed to accommodate at least some of the at least one medium 11, and at least one overpressure protection means 5, which is fluid-connected to the at least one disposable container 1. The at least one overpressure protection means is designed, when triggered, to conduct at least some of the at least one medium 11 into an apparatus region 3a? in front of the overpressure protection means 5 in relation to a flow direction F, in particular into the at least one disposable container 1 and/or into at least one further, second container 1a.

Abstract: A method of filtering a large volume of a medium using a pre-sterilizable, at least partially automated single-use filtration device which includes an unfiltrate inlet, a filtrate outlet, a main line running between the unfiltrate inlet and the filtrate outlet, filter elements arranged in the main line, a venting line and sensors for detecting specific process parameters and regulating means for adjusting specific process parameters, wherein the sensors and regulating means are connected to an external monitoring and control system which is adapted for evaluating and processing sensor data and for piloting the regulating means based on one or more control algorithms, comprises the following process steps: a) filling the single-use filtration device with medium with low flow; b) venting the single-use filtration device through the venting line; c) closing the venting line; d) rinsing the single-use filtration device, in particular the filter elements; e) filtering the medium by means of the filter elements; f)

Abstract: An automated single-use filtration device, in particular for large-volume filtration processes, comprises an unfiltrate inlet, one or more filter elements, a filtrate outlet and sensors for detecting specific process parameters and regulating mechanisms for adjusting specific process parameters. The sensors and regulating mechanisms are connected to an external monitoring and control system, which is adapted for evaluating and processing sensor data and for piloting the regulating mechanisms based on one or more control algorithms.

Abstract: A device (1) is provided for ventilation and integrity testing of a filter unit (2) that can be supplied with pressure. The filter unit (2) has a filter element (9) arranged in a housing (6) between an inlet (7) and an outlet (8). The housing (6) can be ventilated by an air filter (3) connected to the housing interior (12). A filter valve (4) is arranged upstream of the air filter (3) facing the housing interior (12) and connects the air filter (3) to the housing interior (12). The air filter (3) can be connected on its side facing away from the housing interior (12) to a test line (14) for supplying pressure. An inlet valve (5) is arranged upstream of the inlet (7) and connects an inlet line (10) to the housing interior (12).

Abstract: A single-use filtration device (10) comprises a plurality of single-use filter capsules (12) connected with each other by rigid lines, of which at least a part is firmly mounted in a raster universally specified by a holder (14). The filter capsules (12), in particular as regards the type of filter, type of construction and/or size, and/or the connections of the filter capsules (12), are preconfigured for a desired filtration process.

Abstract: A device (1) is provided for ventilation and integrity testing of a filter unit (2) that can be supplied with pressure. The filter unit (2) has a filter element (9) arranged in a housing (6) between an inlet (7) and an outlet (8). The housing (6) can be ventilated by an air filter (3) connected to the housing interior (12). A filter valve (4) is arranged upstream of the air filter (3) facing the housing interior (12) and connects the air filter (3) to the housing interior (12). The air filter (3) can be connected on its side facing away from the housing interior (12) to a test line (14) for supplying pressure. An inlet valve (5) is arranged upstream of the inlet (7) and connects an inlet line (10) to the housing interior (12).

Abstract: The invention relates to a system and a method for cell separation via a filter, with a powder bag which can be arranged in a recirculation circuit and is partly filled with a pulverulent filter aid and to which a cell solution containing the cells to be separated can be delivered from a bioreactor via a pump arranged in the recirculation circuit, the bioreactor, which has an agitator, being arranged in the recirculation circuit, and, when the recirculation circuit is interrupted, the bioreactor being connectable to the filter.

Abstract: The invention relates to a system and a method for cell separation via a filter, with a powder bag which can be arranged in a recirculation circuit and is partly filled with a pulverulent filter aid and to which a cell solution containing the cells to be separated can be delivered from a bioreactor via a pump arranged in the recirculation circuit, the bioreactor, which has an agitator, being arranged in the recirculation circuit, and, when the recirculation circuit is interrupted, the bioreactor being connectable to the filter.

Abstract: The invention relates to a valve device and to a method for transferring a transfer medium, said valve device and method having an inflow, an outflow and two valve disks which are arranged one behind another in the direction of flow and are pivotable about a common rotational axis for opening and closing the lumen which surrounds them, wherein the inflow and the outflow are formed by two housing sections which are lockable together, the ends of which facing one another receive in each case a valve disk with a fixedly connected half-shaft, wherein, with the housing sections in the locked state, the two half-shafts form one common shaft which is pivotable about the rotational axis and the valve disks abut closely against one another, and wherein, with the housing sections in the non-locked state, the valve disks in each case close the lumen of the housing section receiving them.

Abstract: The invention relates to a valve device and to a method for transferring a transfer medium, said valve device and method having an inflow, an outflow and two valve disks which are arranged one behind another in the direction of flow and are pivotable about a common rotational axis for opening and closing the lumen which surrounds them, wherein the inflow and the outflow are formed by two housing sections which are lockable together, the ends of which facing one another receive in each case a valve disk with a fixedly connected half-shaft, wherein, with the housing sections in the locked state, the two half-shafts form one common shaft which is pivotable about the rotational axis and the valve disks abut closely against one another, and wherein, with the housing sections in the non-locked state, the valve disks in each case close the lumen of the housing section receiving them.

Abstract: The invention relates to a crossflow-filtration method for beverages, in particular beer, which comprises the following steps: a) the feed liquid is introduced into a filter module by means of a tangential flow through a filter membrane (6) in a first direction, whereby the filtrate flow on the filtrate side (19) of the filter module is maintained within predetermined threshold values; b) the entry pressure is reduced and the filter is backflushed by surges of filtrate initiated by a reversal of the flow direction transversally to the membrane; c) the feed liquid is optionally introduced in an inverse flow direction to that of step a) and the concentrate is evacuated on the non-filtrate (7) side of the module; d) the entry pressure is reduced and the filter is backflushed by surges of filtrate initiated by a reversal of the flow direction transversally to the membrane; e) steps a) to d) are repeated until the filtrate flow lies below the lower predetermined threshold value; f) to k) the filter is emptied by a

Abstract: The invention relates to a filter element (F), particularly for the static or dead-end filtration of fluids, comprising an inner, essentially hollow supporting core (10) and at least one filter layer (12–14) placed thereon. The inner supporting core (10) is formed as a single piece together with a first end plate (20) and with a second end plate (30). The first end plate (20) comprises a connecting piece (22), which is provided therewith as a single piece and which is fluid-connected to the supporting core (10). The second end plate (30) has a seat (32), which is formed therein, is fluid-connected to the supporting core (10) and is adapted to the shape of the connecting piece (22) whereby enabling a connecting piece (22) of a second structurally identical filter element (F) to be at least partially inserted into the seat (32) in order to establish a fluid connection between the supporting cores (10) of the filter elements (F).

Abstract: The invention relates to a crossflow-filtration method for beverages, in particular beer, which comprises the following steps: a) the feed liquid is introduced into a filter module by means of a tangential flow through a filter membrane (6) in a first direction, whereby the filtrate flow on the filtrate side (19) of the filter module is maintained within predetermined threshold values; b) the entry pressure is reduced and the filter is backflushed by surges of filtrate initiated by a reversal of the flow direction transversally to the membrane; c) the feed liquid is optionally introduced in an inverse flow direction to that of step a) and the concentrate is evacuated on the non-filtrate (7) side of the module; d) the entry pressure is reduced and the filter is backflushed by surges of filtrate initiated by a reversal of the flow direction transversally to the membrane; e) steps a) to d) are repeated until the filtrate flow lies below the lower predetermined threshold value; f) to k) the filter is emptied by a

Abstract: The invention relates to a filter element (F), particularly for the static or dead-end filtration of fluids, comprising an inner, essentially hollow supporting core (10) and at least one filter layer (12-14) placed thereon. The inner supporting core (10) is formed as a single piece together with a first end plate (20) and with a second end plate (30). The first end plate (20) comprises a connecting piece (22), which is provided therewith as a single piece and which is fluid-connected to the supporting core (10). The second end plate (30) has a seat (32), which is formed therein, is fluid-connected to the supporting core (10) and is adapted to the shape of the connecting piece (22) whereby enabling a connecting piece (22) of a second structurally identical filter element (F) to be at least partially inserted into the seat (32) in order to establish a fluid connection between the supporting cores (10) of the filter elements (F).