Patents by Inventor Bernhard Hensel

Bernhard Hensel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240115761
    Abstract: A method for producing a swellable body including bacterial cellulose includes providing a body made of bacterial cellulose, cleaning the body using at least one liquid medium, freezing the body at atmospheric pressure for at least six hours, freeze drying the body, and mechanically pressing the entire molded body or parts thereof after freeze drying of the body. A body of bacterial cellulose is improved regarding its swelling capability.
    Type: Application
    Filed: February 16, 2022
    Publication date: April 11, 2024
    Inventors: Alexander Rzany, Verena Niopek, Bernhard Hensel
  • Publication number: 20230398261
    Abstract: A process for chemical crosslinking of tissue joining partners including crosslinkable groups, such as free amino groups, by a suitable crosslinking agent under static, quasi-static or periodic pulsatile pressure compression. The compression can be in a defined overlap region for seamless, dense and tight tissue closure. This results in a seamless, homogeneous, and at the same time mechanically stable connection/joining of tissue/tissue components. Seamless connected tissue is provided that includes a piece of tissue having at least two tissue parts overlapping each other and the at least two tissue parts overlapping each other that are materially bonded to each other via crosslinked groups of the tissue.
    Type: Application
    Filed: October 28, 2021
    Publication date: December 14, 2023
    Inventors: Alexander Rzany, Daniel Niopek, Nina Foh, Bernhard Hensel
  • Publication number: 20230390050
    Abstract: A method for chemically crosslinking and optionally shaping (including thickness reduction) substantially non-cross-linked tissue, in particular biological tissue, using a permeable material layer. The method can be used in combination with a stepless pressure load/compression on the tissue, so as to always allow fluid transport into and out of the tissue to be treated under the chemical cross-linking; along the lines of drainage. The method can be carried out under different pressure loads/compressions, in particular in order to specifically influence the resulting tissue properties, and, for example, to bring about a homogeneous thickness distribution of the tissue and/or to deliberately and specifically place inhomogeneities, if desired. Furthermore, the method allows the introduction/imprinting of a consistent three-dimensional shape into the tissue to be treated, e.g. of inhomogeneities in the thickness of the tissue.
    Type: Application
    Filed: October 28, 2021
    Publication date: December 7, 2023
    Inventors: Alexander Rzany, Christine Mueller, Nina Foh, Judith Flore Solowiej, Bernhard Hensel
  • Publication number: 20230390051
    Abstract: A process for three-dimensional shaping of a biological and/or artificial tissue/tissue component. The process is consistent for shaping tissues and can produce a desired three-dimensional and permanent shaping of the tissue/tissue component via crosslinking. A suitable crosslinking agent is used in combination with shaped body and a granulate.
    Type: Application
    Filed: October 28, 2021
    Publication date: December 7, 2023
    Inventors: Alexander Rzany, Daniel Niopek, Nina Foh, Bernhard Hensel, Giuseppe Pisani, Matteo Astorino, Davide Mogentale, Kilian Badrutt
  • Publication number: 20230218390
    Abstract: A medical implant, such as a transcatheter deliverable endoprosthesis or a prosthetic heart valve including a stent-structure, one or more skirts and optionally a valve assembly. One or more skirts and/or the one or more leaflets include one or more laser markings that partially or fully penetrate a thickness of the one or more skirts and/or the one or more leaflets. The laser marks are preferably sufficiently big to be optically visible at the surface of the outer skirt by an operator during a sewing process. Each laser marking may be used for suturing, wherein the reduced material thickness eases the suturing/sewing process without compromising the structural integrity of the material of the outer skirt (e.g.
    Type: Application
    Filed: June 9, 2021
    Publication date: July 13, 2023
    Inventors: Giuseppe Pisani, Matteo Astorino, Alexander Rzany, Sabine Weingaertner, Bernhard Hensel, Kilian Badrutt, Davide Mogentale, Nadine Troes, Patrik Markovic
  • Patent number: 11571495
    Abstract: Medical material and a method for preparing a biological tissue for a medical application are provided. The material is useful as a sealing element in a heart valve prosthesis. A method includes decellularizing the biological tissue by decellularizing solution to obtain an acellular extracellular matrix, solubilizing the extracellular matrix of the biological tissue, and crosslinking collagen fibers of the solubilized extracellular matrix.
    Type: Grant
    Filed: November 6, 2017
    Date of Patent: February 7, 2023
    Assignee: BIOTRONIK AG
    Inventors: Alexander Rzany, Wilhelm Erdbruegger, Tobias Kissling, Tobias Igelspacher, Bernhard Hensel
  • Patent number: 11298225
    Abstract: An implant has a support structure (e.g., alloplastic) such as a stent or a scaffold, and a functional element (e.g., a heart valve) including or made of bacterial cellulose. At least a part of the support structure is embedded in the functional element or in an extension thereof so as to connect the functional element to the structural element via positive fit.
    Type: Grant
    Filed: April 18, 2019
    Date of Patent: April 12, 2022
    Assignee: BIOTRONIK AG
    Inventors: Alexander Rzany, Tina Pieger, Bernhard Hensel
  • Publication number: 20190358031
    Abstract: An implant has a support structure (e.g., alloplastic) such as a stent or a scaffold, and a functional element (e.g., a heart valve) including or made of bacterial cellulose. At least a part of the support structure is embedded in the functional element or in an extension thereof so as to connect the functional element to the structural element via positive fit.
    Type: Application
    Filed: April 18, 2019
    Publication date: November 28, 2019
    Inventors: ALEXANDER RZANY, TINA PIEGER, BERNHARD HENSEL
  • Publication number: 20190224369
    Abstract: Medical material and a method for preparing a biological tissue for a medical application are provided. The material is useful as a sealing element in a heart valve prosthesis. A method includes decellularizing the biological tissue by decellularizing solution to obtain an acellular extracellular matrix, solubilizing the extracellular matrix of the biological tissue, and crosslinking collagen fibers of the solubilized extracellular matrix.
    Type: Application
    Filed: November 6, 2017
    Publication date: July 25, 2019
    Inventors: Alexander Rzany, Wilhelm Erdbruegger, Tobias Kissling, Tobias Igelspacher, Bernhard Hensel
  • Publication number: 20170100239
    Abstract: A method for impressing a 3D shape onto a biological tissue, in particular pericardial tissue, during the cross-linking of the tissue, by use of a mold which has a first 3D contact face for laminar contact against an upper side of the tissue and a second 3D contact face for laminar contact against an rear side of the tissue, wherein the tissue is arranged between the two contact faces so that it lies on both sides thereagainst and at the same time is cross-linked by means of a cross-linking agent so that the cross-linked tissue has a 3D shape after removal from the mold. The invention also relates to an implant comprising such a tissue.
    Type: Application
    Filed: September 27, 2016
    Publication date: April 13, 2017
    Inventors: Alexander Rzany, Wilhelm Erdbruegger, Bernhard Hensel
  • Patent number: 9368284
    Abstract: An aluminum electrolytic capacitor including an anode electrode, and a method for producing the anode electrode. The method includes providing an aluminum electrolyte including an ionic liquid and an aluminum salt, galvanically deposing an aluminum on an aluminum foil formed from the aluminum electrolyte, and anodically oxidizing a surface of the aluminum foil. The ionic liquid includes a pyrrolidinium cation and a halogenide. The aluminum electrolyte includes 50-70 mol. % of the aluminum salt based on a total substance amount of the ionic liquid and the aluminum salt. The galvanic deposition includes and is based on a deposition temperature ranging from 20° C. to 100° C., a current density ranging from 1 to 100 mA/cm2, an applied potential ranging from ?0.1 V to ?1.0 V based on a potential of an aluminum reference electrode, and a deposition rate ranging from 1 to 50 ?m/h.
    Type: Grant
    Filed: July 25, 2014
    Date of Patent: June 14, 2016
    Assignee: LITRONIK ENTWICKLUNGS GMBH
    Inventors: Alexander Rzany, Bernhard Hensel, Nicolas Bartilla, Bernd Pretzlaff
  • Publication number: 20150062782
    Abstract: An aluminum electrolytic capacitor including an anode electrode, and a method for producing the anode electrode. The method includes providing an aluminum electrolyte including an ionic liquid and an aluminum salt, galvanically deposing an aluminum on an aluminum foil formed from the aluminum electrolyte, and anodically oxidizing a surface of the aluminum foil. The ionic liquid includes a pyrrolidinium cation and a halogenide. The aluminum electrolyte includes 50-70 mol. % of the aluminum salt based on a total substance amount of the ionic liquid and the aluminum salt. The galvanic deposition includes and is based on a deposition temperature ranging from 20° C. to 100° C., a current density ranging from 1 to 100 mA/cm2, an applied potential ranging from ?0.1V to ?1.0 V based on a potential of an aluminum reference electrode, and a deposition rate ranging from 1 to 50 ?m/h.
    Type: Application
    Filed: July 25, 2014
    Publication date: March 5, 2015
    Applicant: LITRONIK ENTWICKLUNGS GMBH
    Inventors: Alexander Rzany, Bernhard Hensel, Nicolas Bartilla, Bernd Pretzlaff
  • Publication number: 20020193694
    Abstract: An apparatus for characterizing a condition of a myocardium comprising an excitation wave detector which detects an electrical excitation wave propagated through the myocardium at a first (r1) and second point (r2) of the myocardium as a first signal (S1(t)) and a second signal (S2(t)), and an analysis means which is connected to the excitation wave detector and analyzes the first signal (S1(t)) and the second signal (S2(t)), wherein the analysis means detects a difference between a signal shape of the first signal (S1(t)) and the second signal (S2(t)).
    Type: Application
    Filed: March 19, 2002
    Publication date: December 19, 2002
    Applicant: Biotronik Mess- und Therapiegeraete GmbH & Co
    Inventors: Oleg Anosov, Serguej Berdychev, Bernhard Hensel, Ildar Khassanov, Max Schaldach