Patents by Inventor Bernhard Hoffmann

Bernhard Hoffmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12576066
    Abstract: The invention provides methods, compositions, and kits containing an alpha-adrenergic antagonist, such as phentolamine, for use in monotherapy or as part of a combination therapy to treat patients suffering from presbyopia, mydriasis, and/or other ocular disorders.
    Type: Grant
    Filed: January 17, 2025
    Date of Patent: March 17, 2026
    Assignee: Opus Genetics, Inc.
    Inventors: Mina Sooch, Alan R. Meyer, Konstantinos Charizanis, Bernhard Hoffmann, William H. Pitlick
  • Patent number: 12576067
    Abstract: The invention provides methods, compositions, and kits containing an alpha-adrenergic antagonist, such as phentolamine, for use in monotherapy or as part of a combination therapy to treat patients suffering from presbyopia, mydriasis, and/or other ocular disorders.
    Type: Grant
    Filed: January 17, 2025
    Date of Patent: March 17, 2026
    Assignee: Opus Genetics, Inc.
    Inventors: Mina Sooch, Alan R. Meyer, Konstantinos Charizanis, Bernhard Hoffmann, William H. Pitlick
  • Publication number: 20250161274
    Abstract: The invention provides methods, compositions, and kits containing an alpha-adrenergic antagonist, such as phentolamine, for use in monotherapy or as part of a combination therapy to treat patients suffering from presbyopia, mydriasis, and/or other ocular disorders.
    Type: Application
    Filed: January 17, 2025
    Publication date: May 22, 2025
    Inventors: Mina Sooch, Alan R. Meyer, Konstantinos Charizanis, Bernhard Hoffmann, William H. Pitlick
  • Publication number: 20250161275
    Abstract: The invention provides methods, compositions, and kits containing an alpha-adrenergic antagonist, such as phentolamine, for use in monotherapy or as part of a combination therapy to treat patients suffering from presbyopia, mydriasis, and/or other ocular disorders.
    Type: Application
    Filed: January 17, 2025
    Publication date: May 22, 2025
    Inventors: Mina Sooch, Alan R. Meyer, Konstantinos Charizanis, Bernhard Hoffmann, William H. Pitlick
  • Patent number: 12201616
    Abstract: The invention provides methods, compositions, and kits containing an alpha-adrenergic antagonist, such as phentolamine, for use in monotherapy or as part of a combination therapy to treat patients suffering from presbyopia, mydriasis, and/or other ocular disorders.
    Type: Grant
    Filed: July 29, 2022
    Date of Patent: January 21, 2025
    Assignee: Opus Genetics, Inc.
    Inventors: Mina Sooch, Alan R. Meyer, Konstantinos Charizanis, Bernhard Hoffmann, William H. Pitlick
  • Patent number: 12201615
    Abstract: The invention provides methods, compositions, and kits containing an alpha-adrenergic antagonist, such as phentolamine, for use in monotherapy or as part of a combination therapy to treat patients suffering from presbyopia, mydriasis, and/or other ocular disorders.
    Type: Grant
    Filed: July 29, 2022
    Date of Patent: January 21, 2025
    Assignee: Opus Genetics, Inc.
    Inventors: Mina Sooch, Alan R. Meyer, Konstantinos Charizanis, Bernhard Hoffmann, William H. Pitlick
  • Patent number: 12016841
    Abstract: The invention provides methods, compositions, and kits containing an alpha-adrenergic antagonist, such as phentolamine, for use in monotherapy or as part of a combination therapy to treat patients suffering from presbyopia, mydriasis, and/or other ocular disorders.
    Type: Grant
    Filed: March 30, 2022
    Date of Patent: June 25, 2024
    Assignee: Ocuphire Pharma, Inc.
    Inventors: William H. Pitlick, Alan R. Meyer, Mina Sooch, Konstantinos Charizanis, Bernhard Hoffmann
  • Publication number: 20230040217
    Abstract: The invention provides methods, compositions, and kits containing an alpha-adrenergic antagonist, such as phentolamine, for use in monotherapy or as part of a combination therapy to treat patients suffering from presbyopia, mydriasis, and/or other ocular disorders.
    Type: Application
    Filed: July 29, 2022
    Publication date: February 9, 2023
    Inventors: Mina Sooch, Alan R. Meyer, Konstantinos Charizanis, Bernhard Hoffmann, William H. Pitlick
  • Publication number: 20230032637
    Abstract: The invention provides methods, compositions, and kits containing an alpha-adrenergic antagonist, such as phentolamine, for use in monotherapy or as part of a combination therapy to treat patients suffering from presbyopia, mydriasis, and/or other ocular disorders.
    Type: Application
    Filed: July 29, 2022
    Publication date: February 2, 2023
    Inventors: Mina Sooch, Alan R. Meyer, Konstantinos Charizanis, Bernhard Hoffmann, William H. Pitlick
  • Patent number: 11400077
    Abstract: The invention provides methods, compositions, and kits containing an alpha-adrenergic antagonist, such as phentolamine, for use in monotherapy or as part of a combination therapy to treat patients suffering from presbyopia, mydriasis, and/or other ocular disorders.
    Type: Grant
    Filed: April 6, 2020
    Date of Patent: August 2, 2022
    Assignee: Ocuphire Pharma, Inc.
    Inventors: William H. Pitlick, Alan R. Meyer, Mina Sooch, Konstantinos Charizanis, Bernhard Hoffmann
  • Publication number: 20220226287
    Abstract: The invention provides methods, compositions, and kits containing an alpha-adrenergic antagonist, such as phentolamine, for use in monotherapy or as part of a combination therapy to treat patients suffering from presbyopia, mydriasis, and/or other ocular disorders.
    Type: Application
    Filed: March 30, 2022
    Publication date: July 21, 2022
    Inventors: William H. Pitlick, Alan R. Meyer, Mina Sooch, Konstantinos Charizanis, Bernhard Hoffmann
  • Publication number: 20210346349
    Abstract: The invention provides methods, compositions, and kits containing an alpha-adrenergic antagonist, such as phentolamine, for use in monotherapy or as part of a combination therapy to treat patients suffering from presbyopia, mydriasis, and/or other ocular disorders.
    Type: Application
    Filed: April 14, 2021
    Publication date: November 11, 2021
    Inventors: William H. Pitlick, Alan R. Meyer, Mina Sooch, Konstantinos Charizanis, Bernhard Hoffmann
  • Patent number: 10993932
    Abstract: The invention provides methods, compositions, and kits containing an alpha-adrenergic antagonist, such as phentolamine, for use in monotherapy or as part of a combination therapy to treat patients suffering from presbyopia, mydriasis, and/or other ocular disorders.
    Type: Grant
    Filed: April 6, 2020
    Date of Patent: May 4, 2021
    Assignee: Ocuphire Pharma, Inc.
    Inventors: William H. Pitlick, Alan R. Meyer, Mina Sooch, Konstantinos Charizanis, Bernhard Hoffmann
  • Publication number: 20200253931
    Abstract: The invention provides methods, compositions, and kits containing an alpha-adrenergic antagonist, such as phentolamine, for use in monotherapy or as part of a combination therapy to treat patients suffering from presbyopia, mydriasis, and/or other ocular disorders.
    Type: Application
    Filed: April 6, 2020
    Publication date: August 13, 2020
    Inventors: William H. Pitlick, Alan R. Meyer, Mina Sooch, Konstantinos Charizanis, Bernhard Hoffmann
  • Publication number: 20200246310
    Abstract: The invention provides methods, compositions, and kits containing an alpha-adrenergic antagonist, such as phentolamine, for use in monotherapy or as part of a combination therapy to treat patients suffering from presbyopia, mydriasis, and/or other ocular disorders.
    Type: Application
    Filed: April 6, 2020
    Publication date: August 6, 2020
    Inventors: William H. Pitlick, Alan R. Meyer, Mina Sooch, Konstantinos Charizanis, Bernhard Hoffmann
  • Patent number: 10640538
    Abstract: A recombinant dietary protein is provided that is free of phenylalanine and is a dietary protein with a high biological value. Further provided are a vector encoding said dietary protein, a microorganisms expressing said protein, a method for the production of said protein, and a dietary composition comprising said protein that in an embodiment is for use as a medicament and/or food for special medical purposes in patients with accumulations of phenylalanine in the body.
    Type: Grant
    Filed: August 30, 2017
    Date of Patent: May 5, 2020
    Assignee: METAX INSTITUT FÜR DIÄTETIK GMBH
    Inventors: Bernhard Hoffmann, Yvonne Mücke, Stefan Rasche, Natalia Jablonka, Stefan Schillberg
  • Publication number: 20190202872
    Abstract: A recombinant dietary protein is provided that is free of phenylalanine and is a dietary protein with a high biological value. Further provided are a vector encoding said dietary protein, a microorganisms expressing said protein, a method for the production of said protein, and a dietary composition comprising said protein that in an embodiment is for use as a medicament and/or food for special medical purposes in patients with accumulations of phenylalanine in the body.
    Type: Application
    Filed: August 30, 2017
    Publication date: July 4, 2019
    Inventors: Bernhard HOFFMANN, Yvonne MÜCKE, Stefan RASCHE, Natalia JABLONKA, Stefan SCHILLBERG
  • Patent number: 9425656
    Abstract: A transversal flux machine having a stator and an external rotor disposed about the stator, the stator comprising two axial end faces, having an inner core of the stator, having a cooling path disposed radially within the inner core, wherein a cooling path either a) protrudes out of the transversal flux machine on the axial end face of the stator, said transversal flux machine facing away from an inlet side, or b) the cooling path protrudes out of the transversal flux machine on the axial end face of the stator, said transversal flux machine facing away from the inlet side, the cooling path running between the inlet and the outlet in an intermediate space between the stator and the external rotor of the stator facing the inlet side, the cooling path between the inlet and the outlet running in an intermediate space between the stator and the external rotor.
    Type: Grant
    Filed: December 29, 2010
    Date of Patent: August 23, 2016
    Assignee: Robert Bosch GmbH
    Inventors: Reinhard Rasch, Andreas Gruendl, Bernhard Hoffmann, Heidimarie Loos
  • Publication number: 20160159392
    Abstract: A steering knuckle assembly that is made of a lightweight material, such as an aluminum-based material, but is strong enough to withstand various induced stresses like those caused during a press-fit installation of a wheel bearing assembly. In one embodiment, the steering knuckle assembly includes a steering knuckle component made of an aluminum-based material that is over-molded or cast around a reinforcing insert made of a stronger ferrous-based material. The reinforcing insert has an inner surface surrounding an opening that is designed to receive a wheel bearing assembly, where the inner surface can be machined before or after the over-molding or casting process.
    Type: Application
    Filed: August 4, 2014
    Publication date: June 9, 2016
    Inventor: Bernhard Hoffmann
  • Publication number: 20130299299
    Abstract: A clutch has a stationary carrier, a first clutch member and a second clutch member. The first clutch member and the second clutch member are disposed so as to be rotatable about a common axis. The carrier has a coil arrangement, which is partially accommodated in a first partial core containing soft iron and which faces towards the first clutch member. The first clutch member has a second partial core, containing soft iron, having magnetic-flux poles that at least partially enclose the coil arrangement of the stationary carrier. The second clutch member has permanent-magnet elements, which face towards the magnetic-flux poles and which, are at least partially in alignment with at least some of the magnetic-flux poles. The first clutch member and the second clutch member are set up to transmit a torque and/or a rotary motion from the one clutch member to the other clutch member.
    Type: Application
    Filed: May 7, 2013
    Publication date: November 14, 2013
    Applicant: COMPACT DYNAMICS GMBH
    Inventors: BERNHARD HOFFMANN, ANDREAS GRUENDL, REINHARD RASCH