Patents by Inventor Bernhard Horsthemke

Bernhard Horsthemke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CpG island sequencing
    Publication number: 20100075331
    Abstract: The present invention is directed to a method for analyzing the methylation status of a genomic DNA sample, comprising the steps of (i) fragmenting said sample and enriching said sample for sequences comprising CpG islands, (ii) generating a single stranded DNA library, (iii) subjecting said sample to Bisulfite treatment, (iv) clonally amplifying individual members of said single stranded DNA library by means of emulsion PCR, and (v) sequencing said amplified clonally amplified single stranded DNA library.
    Type: Application
    Filed: September 3, 2009
    Publication date: March 25, 2010
    Inventors: Gisela Betzl, Bruno Frey, Epameinondas Fritzilas, Bernhard Horsthemke, Sven Rahmann, Michael Zeschnigk