Abstract: A method and a system described herein provide optimizing image and/or video compression for machine perception. According to an aspect, the method comprises receiving a raw image frame from a camera sensor; detecting a predefined object in the raw image frame and marking a region around the predefined object within the raw image frame as ROI. Based on the ROI, a partitioning scheme, a prediction mode, and quantization parameter are determined for improving coding efficiency. Machine perception efficiency is improved by selecting a quantization parameter table used for compressing and encoding the raw image or video frame based on a selected machine vision task. The selection of the quantization parameter table is based on training of the selected machine vision task using cost function optimization.