Abstract: Aspects of the application provide hemojuvelin antagonists and methods of using the same in treating anemias of kidney disease and conditions associated with these anemias. Methods provided in the application relate to treatment of a subject having an anemia associated with chronic kidney disease and/or kidney disease in a subject that has a level of glomerular filtration rate lower than one or more thresholds.

Abstract: It is provided a vibration damper system for a steering wheel arrangement of a motor vehicle, which is provided for arrangement on a steering wheel element of the steering wheel arrangement. The vibration damper system comprises a vibration damping mass for damping the vibration of the steering wheel arrangement, an elastic bearing element which comprises a fastening element for fastening the elastic bearing element to one of bearing element and vibration damping mass, and a fastening means for fastening to the other of steering wheel element and vibration damping mass, wherein the elastic bearing element sectionally rests against the fastening means.

Abstract: The present invention relates to a silicon carbide substrate for use as a crystal seed, comprising a monocrystalline silicon carbide disk covered with a protective oxide layer. The protective oxide layer is intended to be removed to expose an ideal, clean surface of the monocrystalline silicon carbide disk. The present invention also relates to a method of producing at least one bulk silicon carbide single-crystal by sublimation growth using the silicon carbide substrate with protective oxide layer as a seed crystal. The protective oxide layer is removed from the seed crystal surface to expose the underlying monocrystalline silicon carbide disk by a back-etching process performed in-situ in the crystal growth crucible, i.e. after the seed crystal is arranged inside the growth crucible and before the sublimation deposition on the growth surface starts.

Abstract: In some embodiments, a pressure sensor comprises may comprise a housing, a flexible membrane which, together with the housing, forms a hermetically closed cavity, a sensor element arranged in the hermetically closed cavity, and a gaseous medium in the hermetically closed cavity. The sensor may measure an external pressure on the flexible membrane based on at least one of: a pressure of a gas in the hermetically closed cavity, and/or an amount of time of a time of flight of an optical pulse or a sound pulse emitted by the sensor element reflected from the flexible membrane.

Abstract: Thermal post-treatment of a silicon carbide (SiC) volume monocrystal which has a substantially cylindrical basic shape with a crystal length in an axial direction, a crystal diameter in a radial direction, a crystal central longitudinal axis extending in the axial direction, and with three boundary surfaces, namely, a bottom surface, a top surface and a circumferential edge surface. The SiC volume monocrystal is brought to a post-treatment temperature in order to reduce mechanical stresses present in the SiC volume monocrystal after completion of the previous growth, wherein an inhomogeneous temperature profile with a radial thermal gradient is set in the SiC volume monocrystal, which rises continuously from the crystal central longitudinal axis to the circumferential edge surface, and a heat exchange of the SiC volume monocrystal with a surrounding free space takes place via free heat radiation on at least two of the three boundary surfaces.

Abstract: Provided herein are methods of using the antibodies that bind to RGMc to treat and diagnose iron-related disorders.

Abstract: Provided herein are methods of using the antibodies that bind to RGMc to treat and diagnose iron-related disorders.

Abstract: The present invention relates to systems and methods for growing bulk semiconductor single crystals, and more specifically, for growing bulk semiconductor single crystals, such as silicon carbide, based on physical vapor transport. The sublimation system comprises a crucible (202) having a longitudinal axis (212) and a sidewall (218) extending along the longitudinal axis (212), wherein the crucible (202) comprises a fixing means for at least one seed crystal (210) and at least one source material compartment (204) for containing a source material (208); and a heating system for generating a temperature field around a circumference of the crucible (202) along the longitudinal axis (212) of the crucible (202); a thermally insulating unit (214) arranged within the source material compartment (204) at the sidewall (218) of the crucible (202).

Abstract: The present invention relates to systems and methods for growing bulk semiconductor single crystals, and more specifically, for growing bulk semiconductor single crystals, such as silicon carbide, based on physical vapor transport. The sublimation system comprises a crucible (102) having a longitudinal axis (120) and a sidewall (116) extending along the longitudinal axis (120), wherein the crucible comprises a fixing means for at least one seed crystal (110) and at least one source material compartment (104) for containing a source material (108), and a heating system being formed to generate a temperature field around a circumference of the crucible along the longitudinal axis of the crucible, wherein the crucible (102) comprises at least one first heat radiation cavity (118), which is arranged opposite to the fixing means and adjacent to the source material compartment (104), the first heat radiation cavity (118) being closed on all of its sides.

Abstract: Provided herein are methods of using the antibodies that bind to RGMc to treat and diagnose iron-related disorders.

Abstract: The present invention relates to systems and methods for growing bulk semiconductor single crystals, and more specifically, for growing a bulk semiconductor single crystals, such as silicon carbide, based on physical vapor transport. A sublimation system for growing at least one single crystal of a semiconductor material by means of a sublimation growing process comprises a crucible (102) having a longitudinal axis (120) and comprising a fixing means for at least one seed crystal (110) and at least one source material compartment (104) for containing a source material (108); a heating system being formed to generate an irregular temperature field around a circumference of the crucible at one or more defined heights along the longitudinal axis of the crucible; a rotary drive that is operable to cause a rotational movement of the fixing means around the longitudinal axis relative to the heating system.

Abstract: The present invention relates to systems and methods for growing bulk semiconductor single crystals, and more specifically, for growing a bulk semiconductor single crystals, such as silicon carbide, based on physical vapor transport. A sublimation system for growing at least one single crystal of a semiconductor material by means of a sublimation growing process comprises a crucible (102) having a longitudinal axis (120) and comprising a fixing means for at least one seed crystal (110) and at least one source material compartment (104) for containing a source material (108); a heating system being formed to generate an irregular temperature field around a circumference of the crucible (102) and/or along the longitudinal axis of the crucible (102); a thermal insulation unit (117) at least partly surrounding the crucible (102), wherein the thermal insulation unit (117) has a radially and/or axially asymmetric form to compensate the irregular temperature field.

Abstract: A piston rod unit and a method for producing a piston rod unit, or a shaft, in light-weight construction, with a rod which is hollowly-drilled by means of a deep bore into the rod shank, and the resulting rod opening is closed subsequently by means of a forging process.

Abstract: Aspects of the application provide anti-hemojuvelin antibodies and methods of using the same in treating anemias of chronic disease, iron-restricted anemias, and/or conditions associated with anemia.

Abstract: Aspects of the application provide anti-hemojuvelin antibodies and methods of using the same in treating myelofibrosis and/or conditions associated with myelofibrosis.

Abstract: The disclosure relates to a clutch assembly for a manual transmission of a motor vehicle, having an axially running transmission input shaft which, by way of a clutch having a central release mechanism disposed on the transmission input shaft, is able to be coupled to a motor output shaft. The transmission input shaft has at least one ferromagnetic measuring portion. The magnetization of the ferromagnetic measuring portion is able to be influenced in a magnetoelastic manner by a torsion of the transmission input shaft. Portions of the central release mechanism surround the at least one measuring portion and has a sensor device which is specified for measuring a variable as a function of the magnetization of at least one measuring portion.

Abstract: An access system and a method for a vehicle, having at least one vehicle-mounted motion sensor and at least one motion sensor that can be carried by a person, in each case for sensing a single sequence of motions of the person moving outside of the vehicle and carrying the portable motion sensor, an access control unit of the vehicle for locking and/or unlocking at least one door of the vehicle and a controller for comparing the sequence of motions of the person sensed via the vehicle-mounted motion sensor with the sequence of motions of the person sensed via the portable motion sensor, wherein the access control unit can be actuated by the controller as a function of the comparison of the two sequences of motions in such a manner that the access control unit automatically locks or automatically unlocks the at least one door.

Abstract: A piston rod unit and a method for producing a piston rod unit, or a shaft, in light-weight construction, with a rod which is hollowly-drilled by means of a deep bore into the rod shank, and the resulting rod opening is closed subsequently by means of a forging process.

Abstract: The invention relates to a method for producing a piston rod unit, or a shaft, in lightweight construction, with a rod which is hollowly-drilled by means of a deep bore into the rod shank, and the resulting rod opening is closed subsequently by means of a forging process.

Abstract: A method for producing a curved tubular connection element has at least the following production steps: machining a linearly extending metal tube piece (10) with a specifiable length while incorporating connection geometries (12, 14) for receiving separate connection parts (18, 20) to connect a media-conducting piping; carrying out a bending process for the tube piece (10) produced by being machined with a specifiable bending radius, preferably up to 90 degrees; and attaching each connection part (18, 20) to the respective connection geometry (12, 14) that can be paired with it.