Abstract: The present invention relates to an apparatus for automatic adjustment of a treatment of a target person to be treated based on calculated recovery prediction data for predicting a change of a sensory function of said target person in response to said treatment.

Abstract: An apparatus for stimulating a brain (3B) of a person (2) comprising a detector (10) for detecting an induced or a spontaneous physiological signal generated by the brain (3B), a control unit (12) being connected to said detector (10) for comparing the detected physiological signal with a criterion to determine an optimal setting of a variable signal parameter, a first signal generator (8) for applying an electrical stimulation signal (EES) to said person (2) and/or at least one second signal generator (9) for applying a sensory stimulation signal (SSS) to a sensory organ (3A) of said person (2), wherein a signal parameter of the stimulation signals (ESS, SSS) are adjusted to the determined optimal setting of said signal parameter.

Abstract: A training device for training at least one user comprising a user output interface (3) for presenting at least one training task (t) to said user (2), a user input interface (4) for inputting a response of said user (2) to each presented training task (t), means (5) for detecting a performance (p) of said user (2) on the basis of the responses input by said user (2), and means (6) for presenting rewards for the detected performance (p) of said user, wherein said rewards are selected depending on a training date (TD) on which the responses are input by said user (2) and depending on an age (A) of said user (2).

Abstract: The present invention relates to an apparatus for automatic adjustment of a treatment of a target person to be treated based on calculated recovery prediction data for predicting a change of a sensory function of said target person in response to said treatment.

Abstract: A device and method are provided for treating the visual system of a human including the retina, visual cortex and/or other neuro-cellular structures. The method includes the steps of locating and defining a blind zone of deteriorated vision within the human's visual system, defining a treatment area which is located predominantly within the blind zone, and treating the human's visual system by presenting visual stimuli to the human's visual system. The majority of the visual stimuli are presented to at least a portion of the blind zone.

Abstract: Systems and methods for treating a retinal disease in a human include locating and defining one or more zones of vision within the human's visual system and defining a treatment area which is located within at least one of the zones. The method of this embodiment may also include treating the human's retinal disease by presenting visual stimuli to the treatment area at a specified location and with a specified definition and recording changes in specified characteristics of the human's visual system. The method of this embodiment may also include reiterating the previous steps so as to improve the human's overall visual system.

Abstract: Systems and methods for treating a retinal disease in a human include locating and defining one or more zones of vision within the human's visual system and defining a treatment area which is located within at least one of the zones. The method of this embodiment may also include treating the human's retinal disease by presenting visual stimuli to the treatment area at a specified location and with a specified definition and recording changes in specified characteristics of the human's visual system. The method of this embodiment may also include reiterating the previous steps so as to improve the human's overall visual system.

Abstract: A training device for training at least one user comprising a user output interface (3) for presenting at least one training task (t) to said user (2), a user input interface (4) for inputting a response of said user (2) to each presented training task (t), means (5) for detecting a performance (p) of said user (2) on the basis of the responses input by said user (2), and means (6) for presenting rewards for the detected performance (p) of said user, wherein said rewards are selected depending on a training date (TD) on which the responses are input by said user (2) and depending on an age (A) of said user (2).

Abstract: A head-guide for diagnosing or training vision of a user and methods of user thereof are disclosed. The head-guide may include a head-support for orienting a head of the user, a display-support for orienting a display. The head-guide may also include a guide-support connected to the head-support and the display-support. The head-support and display-support may be pre-configured to fix the relative position of the head and the display and the display may present visual stimuli to diagnose or train the vision of the user.

Abstract: An apparatus for stimulating a brain (3B) of a person (2) comprising a detector (10) for detecting an induced or a spontaneous physiological signal generated by the brain (3B), a control unit (12) being connected to said detector (10) for comparing the detected physiological signal with a criterion to determine an optimal setting of a variable signal parameter, a first signal generator (8) for applying an electrical stimulation signal (EES) to said person (2) and/or at least one second signal generator (9) for applying a sensory stimulation signal (SSS) to a sensory organ (3A) of said person (2), wherein a signal parameter of the stimulation signals (ESS, SSS) are adjusted to the determined optimal setting of said signal parameter.

Abstract: The invention relates to the use of DNA-loaded nanoparticles for a transfection of DNA into cells in vitro or in vivo.

Abstract: The present invention relates to a process for training the visual system of a human by presenting optical stimuli to said human, said stimuli being presented to a zone within the intact visual field of said human and optionally to a zone outside the intact visual field of said human, one of said zones comprising a zone to be trained, thereby allowing an improvement of the vision in general, said process comprising the steps of (a) locating and defining a zone of intact vision and optionally a zone of deteriorated vision or residual visual function or partial visual system injury (“transition zone”) within the human's visual system; (b) defining a training area which is located within at least one of said zones including the zone of intact vision; (c) training the human's visual system by presenting visual stimuli to the human's visual system, at least a part of said visual stimuli being presented in or near said zone of intact vision; (d) recording changes in the characteristics of the human's visual system;

Abstract: A method and device for treating the visual system of a human is provided. The method comprises situating the human in proximity to a computer-actuated light emitting array that has a set of individually actuable elements. A campimetric representation of the visual field is used to select a stimulus distribution. An actuable element subset is selected from the set of individually actuable elements based on the stimulus distribution. The subset of elements is actuated to emit a light stimulus that is directed to a specified region of the human's visual field. The stimulus distribution may be biased toward the central visual field or based on apportioning among specified zones. The distribution may also be based on a transition zone.

Abstract: A device and method are provided for treating the visual system of a human including the retina, visual cortex and/or other neuro-cellular structures. The method includes the steps of locating and defining a blind zone of deteriorated vision within the human's visual system, defining a treatment area which is located predominantly within the blind zone, and treating the human's visual system by presenting visual stimuli to the human's visual system. The majority of the visual stimuli are presented to at least a portion of the blind zone.

Abstract: A head mounted display for diagnosing or training vision of a subject. In one embodiment, the head mounted display includes a first display that presents a first visual image to a first eye of the subject in an identified position of regard with respect to a specified zone in the field of view of the subject. This embodiment may also include a second display that presents a second visual image to a second eye of the subject in an identified position of regard with respect to a specified zone in the field of view of the subject. This embodiment may also include an anterior support section coupled to the first and second displays, the anterior support section orienting the display in front of the eyes of the subject and may also include a posterior support section coupled to the anterior support section.

Abstract: Systems and methods for treating a retinal disease in a human include locating and defining one or more zones of vision within the human's visual system and defining a treatment area which is located within at least one of the zones. The method of this embodiment may also include treating the human's retinal disease by presenting visual stimuli to the treatment area at a specified location and with a specified definition and recording changes in specified characteristics of the human's visual system. The method of this embodiment may also include reiterating the previous steps so as to improve the human's overall visual system.

Abstract: A head-guide for diagnosing or training vision of a user and methods of user thereof are disclosed. The head-guide may include a head-support for orienting a head of the user, a display-support for orienting a display. The head-guide may also include a guide-support connected to the head-support and the display-support. The head-support and display-support may be pre-configured to fix the relative position of the head and the display and the display may present visual stimuli to diagnose or train the vision of the user.

Abstract: A composition and method of fabrication are presented with which nanoparticles may be used as a tool to deliver drugs to a specific target within or on a mammalian body. Specifically, by using stabilizers other than Dextran 70.000 during the polymerization process, according to the present invention, surfactants, which were deemed necessary coating material in the prior art, are no longer required. This is a significant simplification of the fabrication procedure. Many substances are useful as stabilizers, but the preferred stabilizers comprise Dextran 12.000 or polysorbate 85. In the present invention a drug is either incorporated into or adsorbed onto the stabilized nanoparticles. This drug/nanoparticle complex is then administered to the organism on any route such as by oral application, injection or inhalation, whereupon the drug exerts its effect at the desired site of pharmacological action.

Abstract: The present invention relates to a process for training the visual system of a human by presenting optical stimuli to said human, said stimuli being presented to a zone within the intact visual field of said human and optionally to a zone outside the intact visual field of said human, one of said zones comprising a zone to be trained, thereby allowing an improvement of the vision in general, said process comprising the steps of (a) locating and defining a zone of intact vision and optionally a zone of deteriorated vision or residual visual function or partial visual system injury (“transition zone”) within the human's visual system; (b) defining a training area which is located within at least one of said zones including the zone of intact vision; (c) training the human's visual system by presenting visual stimuli to the human's visual system, at least a part of said visual stimuli being presented in or near said zone of intact vision; (d) recording changes in the characteristics of the human's visual system;

Abstract: The invention relates to the use of DNA-loaded nanoparticles for a transfection of DNA into cells in vitro or in vivo.