Patents by Inventor Bernhard Schmied

Bernhard Schmied has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hirudin/polyalkylene glycol conjugates and hirudin muteins
    Patent number: 5663141
    Abstract: Hirudin/polyalkylene glycol derivatives of the formula[A--(CH.sub.2).sub.n --[O--(CH.sub.2).sub.nlm --B--].sub.p Hir [sic]Iand hirudin muteins and the preparation thereof are described. The compounds are suitable for controlling diseases.
    Type: Grant
    Filed: May 29, 1992
    Date of Patent: September 2, 1997
    Assignee: BASF Aktiengesellschaft
    Inventors: Manfred Kurfuerst, Klaus Ruebsamen, Bernhard Schmied, Wolfgang Koerwer, Juergen Schweden, Hans Wolfgang Hoeffken
  • Process for the preparation of expandable polystyrene
    Patent number: 5591778
    Abstract: The invention relates to a process for the preparation of bead shaped, expandable polystyrene by the polymerization of styrene in an aqueous suspension in the presence of dimeric .alpha.-methylstyrene as a regulator and a C.sub.3 to C.sub.6 hydrocarbon as a blowing agent, whereby one first reports the content of saturated hydrocarbons, having a boiling point between 70.degree. and 170.degree. C., in the styrene and dimeric .alpha.-methylstyrene, and then enough saturated hydrocarbons, having a boiling point from 70.degree. to 170.degree. C., are added before, during or after the polymerization so that their total content in the suspension is from 0.1 to 0.8 weight percent, based on the styrene.
    Type: Grant
    Filed: August 14, 1995
    Date of Patent: January 7, 1997
    Assignee: BASF Aktiengesellschaft
    Inventors: Dietrich Scherzer, Klaus Hahn, Anthony Schaefer, Bernhard Schmied
  • Peptides with anticoagulant activity
    Patent number: 5393873
    Abstract: Peptides of the formula ##STR1## where X, A.sup.1 -A.sup.7 Y and W have the meanings stated in the description, and the preparation thereof are described. The peptides are suitable for controlling diseases.
    Type: Grant
    Filed: July 29, 1993
    Date of Patent: February 28, 1995
    Assignee: BASF Aktiengesellschaft
    Inventors: Bernhard Schmied, Hans W. Hoeffken, Wilfried Hornberger, Harald Bernard
  • Sulfonamide derivatives and drugs obtained therefrom
    Patent number: 4999345
    Abstract: Sulfonamide derivatives of the formula I ##STR1## where R.sup.1 is a C.sub.1 -C.sub.4 -alkyl or phenyl group which may be substituted by halogen, trifluoromethyl or C.sub.1 -C.sub.4 -alkyl, R.sup.2 is hydrogen or C.sub.1 -C.sub.4 -alkyl, A is a group CHOR.sup.3 C.dbd.O, C.dbd.S or C.dbd.N--OR.sup.4, R.sup.3 is hydrogen, C.sub.1 -C.sub.4 -alkyl phenyl, benzyl or C.sub.1 -C.sub.4 -acyl, R.sup.4 is hydrogen or methyl, B may be methylene or ethylene in the m or p position or, of A is not carbonyl, may be methyleneoxy, the oxygen atom being bonded to the aromatic, and E is a carboxyl, phosphonic acid or sulfo radical, their physiologically acceptable salts, esters with C.sub.1 -C.sub.4 -alcohols or amides or the tetrazol-5-yl radical, their preparation and their use as drugs.
    Type: Grant
    Filed: May 26, 1989
    Date of Patent: March 12, 1991
    Assignee: BASF Aktiengesellschaft
    Inventors: Bernhard Schmied, Hand D. Lehmann, Verena Baldinger, Klaus Ruebsamen
  • Mixture of a substance having thrombolytic activity and of an antithrombotic substance
    Patent number: 4944943
    Abstract: A mixture of a substance having thrombolytic activity and of an antithrombotic substance which is suitable for controlling vascular disorders caused by thrombosis is described.
    Type: Grant
    Filed: February 13, 1989
    Date of Patent: July 31, 1990
    Assignee: BASF Aktiengesellschaft
    Inventors: Volker Eschenfelder, Bernhard Schmied, Klaus Ruebsamen
  • Pyrrol-1-ylphenyldihydropyridazinones, their preparation and their use
    Patent number: 4710496
    Abstract: Novel pyrrol-1-ylphenyldihydropyridazinones of the formula ##STR1## their preparation and their use in the treatment of disorders.
    Type: Grant
    Filed: July 9, 1985
    Date of Patent: December 1, 1987
    Assignee: BASF Aktiengesellschaft
    Inventors: Karl-Heinz Geiss, Bernhard Schmied, Manfred Raschack, Hans-Dieter Lehmann, Josef Gries, Klaus Ruebsamen