Patents by Inventor Bernward Husemann
Bernward Husemann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230407229Abstract: A computer-implemented method can configure and/or setup and/or control a downstream process for processing a biomass, including receiving at least one measurement value of at least one feature of an upstream process by which the biomass to be processed in the downstream process has been obtained and/or of at least one feature of a downstream process stage or operation, determining at least one downstream process parameter based on the received at least one measurement value, arid configuring and/or setup and/or controlling at least one downstream process stage or process operation based on the determined at least one downstream process parameter.Type: ApplicationFiled: October 6, 2021Publication date: December 21, 2023Applicant: Sartorius Stedim Biotech GmbHInventors: Marco Leupold, Alexandre Espachs Barroso, Bernward Husemann, Michael Rodenberg, Jens Matuszczyk, Markus Kampmann, Martin Leuthold, Johannes Wortmeyer, Thomas Friese, Jochen Scholz
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Patent number: 11827874Abstract: A bioreactor (1; 2; 3) includes a receiving container (10) for receiving a disposable bag (44). A bottom surface (11) of the receiving container (10) is designed to support the disposable bag (44) in the receiving container (10). An outlet opening (5) is formed in the bottom surface (11) and tapers down with respect to the ground for receiving a drain port (45) of the disposable bag (44). The drain port is complementary to the outlet opening (5).Type: GrantFiled: January 25, 2021Date of Patent: November 28, 2023Assignee: Sartorius Stedim Biotech GmbHInventors: Bernward Husemann, Simon Topp-Manske, Bjoern Nickel, Marco Leupold
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Patent number: 11697790Abstract: A probe holder (1), for positioning at least one probe (50) such that the probe (50) at least partially engages in a system (100) for biotechnological uses, comprises a holder base (10) for positioning the probe holder (1) on the system (100) for biotechnological uses and at least one probe positioning means (20), which is designed to position the at least one probe (50) such that the probe (50) extends in a probe extension direction (S; S1, S2, S3, S4). The probe positioning means (20) is positioned on the holder base (10) such that the position of the probe (50) is variably adjustable in a probe extension direction (S; S1, S2, S3, S4).Type: GrantFiled: March 14, 2017Date of Patent: July 11, 2023Assignee: Sartorius Stedim Blotech GmbHInventors: Simon Topp-Manske, Christian Zahnow, Ute Husemann, Bernward Husemann
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Patent number: 11124753Abstract: A system for receiving a disposable bag (44) has a receiving container (10) with a container interior for receiving the disposable bag (44) and a temperature-control hollow wall (20) that at least partially surrounds the container interior of the receiving container (10). A temperature-control unit controls the temperature of the container interior by will a temperature-control medium arranged in the temperature-control hollow wall (20) at a maximum pressure of about 1 bar.Type: GrantFiled: March 8, 2016Date of Patent: September 21, 2021Inventors: Bernward Husemann, Simon Topp-Manske, Bjorn Nickel, Marco Leupold
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Publication number: 20210139835Abstract: A bioreactor (1; 2; 3) includes a receiving container (10) for receiving a disposable bag (44). A bottom surface (11) of the receiving container (10) is designed to support the disposable bag (44) in the receiving container (10). An outlet opening (5) is formed in the bottom surface (11) and tapers down with respect to the ground for receiving a drain port (45) of the disposable bag (44). The drain port is complementary to the outlet opening (5).Type: ApplicationFiled: January 25, 2021Publication date: May 13, 2021Inventors: Bernward Husemann, Simon Topp-Manske, Bjoern Nickel, Marco Leupold
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Patent number: 10947489Abstract: A bioreactor (1; 2; 3) includes a receiving container (10) for receiving a disposable bag (44). A bottom surface (11) of the receiving container (10) is designed to support the disposable bag (44) in the receiving container (10). An outlet opening (5) is formed in the bottom surface (11) and tapers down with respect to the ground for receiving a drain port (45) of the disposable bag (44). The drain port is complementary to the outlet opening (5).Type: GrantFiled: March 8, 2016Date of Patent: March 16, 2021Inventors: Bernward Husemann, Simon Topp-Manske, Bjoern Nickel, Marco Leupold
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Publication number: 20200283710Abstract: A container (1, 1b) of a bioreactor (1a, 1b) has a container interior (22) designed for being filled with a medium (8) including a photoreactive material, and designed for at least partially triggering a photochemical reaction of the photoreactive material. The container (1, 1b) has at least one illuminant receiving pouch (11) that is at least partially transparent for an electromagnetic radiation (14), and that is arranged on a illuminant opening (12) within the container interior (22) and is designed to receive at least one illuminant (15, 15a, 15b, 15c, 15d, 15e) from an outer side (A) through the illuminant opening (12, 12a, 12b). The illuminant at least partially irradiates the medium (8) such that the photochemical reaction of the photoreactive material can be triggered by electromagnetic radiation (14) emitted by the illuminant and the illuminant is isolated in relation to the medium (8) by the illuminant receiving pouch (11).Type: ApplicationFiled: September 6, 2018Publication date: September 10, 2020Inventors: Marco Leupold, Bernward Husemann, Simon Topp-Manske, Christian Grimm
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Patent number: 10619128Abstract: A container (1) has a flexible wall (2) and at least one emptying tube (4, 4?, 4?) that projects through a wall aperture (7) into the container interior (3) surrounded by the flexible wall (2). The free end (12) of the emptying tube has an emptying opening (13) that can be set in position vertically to different emptying heights (14). The container (1) is distinguished in that an adapter piece (8), in which the emptying tube (4, 4?, 4?) is held in a longitudinally displaceable manner, is arranged in the wall aperture and in that a portion of the emptying tube (4, 4?, 4?) is surrounded by a flexible sheath (5) that is connected at a first end (11) to the emptying tube (4, 4?, 4?) and at its second end (10), which is remote from the first end (11), to the wall (2) or the adapter piece (8).Type: GrantFiled: August 18, 2014Date of Patent: April 14, 2020Assignee: SARTORIUS STEDIM BIOTECH GMBHInventors: Bernward Husemann, Gerhard Greller, Wolfgang Kahlert, Heinz-Ruediger Keitel, Davy de Wilde
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Patent number: 10233417Abstract: A container (2) has flexible walls surrounding a container interior (6). At least one electrical sensor (3, 3?, 3?, 3??, 3??) projects into the container interior (6) and has at least first and second electrically conductive plates (8, 8?, 9, 9?, 9??) for determining the conductivity or impedance of a medium that surrounds the plates (8, 8?, 9, 9?, 9??). The plates (8, 8?, 9, 9?, 9??) are connected via connecting lines (10, 11) to a control and regulating unit (4) outside the container interior (6). At least the first plate (8, 8?) is on a closed free end of a sheathing (5, 5?, 5??) and has a contact area exposed to the surrounding medium. The sheathing (5, 5?, 5??, 17, 17??) is a flexible hose (7) or bellows (19, 19??) through which the electrical connecting line (10, 11) of the plate (8, 8?, 9, 9?, 9??) is routed.Type: GrantFiled: August 21, 2014Date of Patent: March 19, 2019Assignee: Sartorius Stedim Biotech GmbHInventors: Heinz-Ruediger Keitel, Bernward Husemann, Wolfgang Kahlert
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Patent number: 10202575Abstract: A system (1) is provided for switching over exhaust air of a bioreactor (2) that has a disposable container (3). The system (1) has at least two exhaust air ducts (4, 5) connecting the disposable container (3) to exhaust air filters (6, 7, 18, 18?). A valve (8) is disposed in at least one of the at least two exhaust air ducts (4, 5) and enables the associated exhaust air filter (6, 7, 18, 18?) to be freed.Type: GrantFiled: March 22, 2014Date of Patent: February 12, 2019Assignee: Sartorius Stedim Biotech GmbHInventors: Wolfgang Kahlert, Ralf Hartmann, Bernward Husemann
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Publication number: 20190031996Abstract: A probe holder (1), for positioning at least one probe (50) such that the probe (50) at least partially engages in a system (100) for biotechnological uses, comprises a holder base (10) for positioning the probe holder (1) on the system (100) for biotechnological uses and at least one probe positioning means (20), which is designed to position the at least one probe (50) such that the probe (50) extends in a probe extension direction (S; S1, S2, S3, S4). The probe positioning means (20) is positioned on the holder base (10) such that the position of the probe (50) is variably adjustable in a probe extension direction (S; S1, S2, S3, S4).Type: ApplicationFiled: March 14, 2017Publication date: January 31, 2019Inventors: Simon Topp-Manske, Christian Zahnow, Ute Husemann, Bernward Husemann
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Patent number: 10130922Abstract: A receptacle has a wall defining a receptacle interior and a shaft housing for guiding a shaft through the wall into the receptacle interior. The shaft housing defines an annular cap with spaced apart inner and outer walls connected by an inner end face facing the receptacle interior. A shaft guide part has an end facing the receptacle interior and an outer surface that defines a gap relative to the inner wall of the shaft housing. The shaft guide part has an annular wall spaced apart from and parallel to its outer surface. The annular wall extends over the free end of the inner wall of the shaft housing and is sealed to the inner and outer walls of the shaft housing by at least one seal each. The shaft guide part is mounted in the shaft housing by a radial ball bearing and by an axial ball bearing.Type: GrantFiled: May 28, 2014Date of Patent: November 20, 2018Assignee: SARTORIUS STEDIM BIOTECH GMBHInventors: Reiner Seitz, Rainer Salzmann, Thomas Regen, Matthias Hielscher, Bernward Husemann, Stefan Zeuch, Ute Husemann, Gerhard Greller
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Publication number: 20180187140Abstract: A bioreactor (1; 2; 3) includes a receiving container (10) for receiving a disposable bag (44). A bottom surface (11) of the receiving container (10) is designed to support the disposable bag (44) in the receiving container (10). An outlet opening (5) is formed in the bottom surface (11) and tapers down with respect to the ground for receiving a drain port (45) of the disposable bag (44). The drain port is complementary to the outlet opening (5).Type: ApplicationFiled: March 8, 2016Publication date: July 5, 2018Inventors: Bernward Husemann, Simon Topp-Manske, Bjoern Nickel, Marco Leupold
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Publication number: 20180163164Abstract: A system for receiving a disposable bag (44) has a receiving container (10) with a container interior for receiving the disposable bag (44) and a temperature-control hollow wall (20) that at least partially surrounds the container interior of the receiving container (10). A temperature-control unit controls the temperature of the container interior by will a temperature-control medium arranged in the temperature-control hollow wall (20) at a maximum pressure of about 1 bar.Type: ApplicationFiled: March 8, 2016Publication date: June 14, 2018Inventors: Bernward HUSEMANN, Simon TOPP-MANSKE, Bjorn NICKEL, Marco LEUPOLD
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Patent number: 9994806Abstract: A transport device for a container has a base, a vertical member extending up from the base and a complementary handling unit extending from an end of the vertical member spaced from the base. The complementary handling unit is configured for releasably engaging a container, such as a bioreactor container, so that the container can be transported to a holding device.Type: GrantFiled: November 8, 2016Date of Patent: June 12, 2018Assignee: Sartorius Stedim Biotech GmbHInventors: Bernward Husemann, Wolfgang Kahlert, Sebastien Chaussin, Reiner Seitz
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Patent number: 9695391Abstract: One aspect relates to a container for inserting into a holding device, comprising: a wall that is flexible at least in some areas, which wall is squashed, at least in some areas, in a transport condition in a direction opposite to a stretching direction; a handling unit connected to the wall, which is designed to come into engagement with a complementary handling unit of a transport device; a securing unit which in a transport condition hinders stretching of the wall of the bioreactor container along the stretching direction, wherein the container can, when the securing unit is released, be extended at least in some areas along the stretching direction, as well as a transport device, a use and a method.Type: GrantFiled: February 4, 2014Date of Patent: July 4, 2017Assignee: Sartorius Stedim Biotech GmbHInventors: Bernward Husemann, Wolfgang Kahlert, Sebastien Chaussin, Reiner Seitz
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Publication number: 20170051240Abstract: A transport device for a container has a base, a vertical member extending up from the base and a complementary handling unit extending from an end of the vertical member spaced from the base. The complementary handling unit is configured for releasably engaging a container, such as a bioreactor container, so that the container can be transported to a holding device.Type: ApplicationFiled: November 8, 2016Publication date: February 23, 2017Inventors: Bernward Husemann, Wolfgang Kahlert, Sebastien Chaussin, Reiner Seitz
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Publication number: 20160215247Abstract: A container (1) has a flexible wall (2) and at least one emptying tube (4, 4?, 4?) that projects through a wall aperture (7) into the container interior (3) surrounded by the flexible wall (2). The free end (12) of the emptying tube has an emptying opening (13) that can be set in position vertically to different emptying heights (14). The container (1) is distinguished in that an adapter piece (8), in which the emptying tube (4, 4?, 4?) is held in a longitudinally displaceable manner, is arranged in the wall aperture and in that a portion of the emptying tube (4, 4?, 4?) is surrounded by a flexible sheath (5) that is connected at a first end (11) to the emptying tube (4, 4?, 4?) and at its second end (10), which is remote from the first end (11), to the wall (2) or the adapter piece (8).Type: ApplicationFiled: August 18, 2014Publication date: July 28, 2016Inventors: Bernward Husemann, Gerhard Greller, Wolfgang Kahlert, Heinz-Ruediger Keitel, Davy de Wilde
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Publication number: 20160215248Abstract: A container (2) has flexible walls surrounding a container interior (6). At least one electrical sensor (3, 3?, 3?, 3??, 3??) projects into the container interior (6) and has at least first and second electrically conductive plates (8, 8?, 9, 9?, 9??) for determining the conductivity or impedance of a medium that surrounds the plates (8, 8?, 9, 9?, 9??). The plates (8, 8?, 9, 9?, 9??) are connected via connecting lines (10, 11) to a control and regulating unit (4) outside the container interior (6). At least the first plate (8, 8?) is on a closed free end of a sheathing (5, 5?, 5??) and has a contact area exposed to the surrounding medium. The sheathing (5, 5?, 5??, 17, 17??) is a flexible hose (7) or bellows (19, 19??) through which the electrical connecting line (10, 11) of the plate (8, 8?, 9, 9?, 9??) is routed.Type: ApplicationFiled: August 21, 2014Publication date: July 28, 2016Inventors: Heinz-Ruediger Keitel, Bernward Husemann, Wolfgang Kahlert
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Publication number: 20160151749Abstract: A receptacle has a wall defining a receptacle interior and a shaft housing for guiding a shaft through the wall into the receptacle interior. The shaft housing defines an annular cap with spaced apart inner and outer walls connected by an inner end face facing the receptacle interior. A shaft guide part has an end facing the receptacle interior and an outer surface that defines a gap relative to the inner wall of the shaft housing. The shaft guide part has an annular wall spaced apart from and parallel to its outer surface. The annular wall extends over the free end of the inner wall of the shaft housing and is sealed to the inner and outer walls of the shaft housing by at least one seal each. The shaft guide part is mounted in the shaft housing by a radial ball bearing and by an axial ball bearing.Type: ApplicationFiled: May 28, 2014Publication date: June 2, 2016Inventors: Reiner Seitz, Rainer Salzmann, Thomas Regen, Matthias Hielscher, Bernward Husemann, Stefan Zeuch, Ute Husemann, Gerhard Greller