Patents by Inventor Bert Binas

Bert Binas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for making cells with an extra-embryonic endodermal precursor phenotype
    Patent number: 9388388
    Abstract: The invention is directed to methods for making cells in vitro that have an extra-embryonic endodermal precursor phenotype. The method involves culturing cells from blastocysts under specific defined conditions.
    Type: Grant
    Filed: January 30, 2012
    Date of Patent: July 12, 2016
    Assignees: Katholieke Universiteit Leuven, Hanyang University of Korea
    Inventors: Catherine M. Verfaillie, Bert Binas
  • Methods for Making Cells with an Extra-Embryonic Endodermal Precursor Phenotype
    Publication number: 20140057313
    Abstract: The invention is directed to methods for making cells in vitro that have an extra-embryonic endodermal precursor phenotype. The method involves culturing cells from blastocysts under specific defined conditions.
    Type: Application
    Filed: January 30, 2012
    Publication date: February 27, 2014
    Inventors: Catherine M. Verfaillie, Bert Binas
  • Use of cells derived from embryonic stem cells for increasing transplantation tolerance and for repairing damaged tissue
    Publication number: 20040208857
    Abstract: The invention relates to the use of cells from cell lines, which are derived from early embryonic stages, for the donor-specific increase in transplantation tolerance and for repairing damaged tissue. Areas of application of the invention include the field of medicine and the pharmaceutical industry. The aim of the invention is to produce a donor-specific immunotolerance in order to prevent a rejection of the transplanted tissue due to an immune response and thus to be able to limit the administration of immune suppressive agents. In order to produce a donor-specific immunotolerance, embryonic stem cell-like cell lines (ECL) are obtained from blastocysts and are transfected with genetic material of the donor, which codes for the MHC haplotypes. The cells produced in such a manner are administered to the recipient before the transplantation for producing an immunotolerance against the tissue to be transplanted or for regenerating already damaged tissue.
    Type: Application
    Filed: January 22, 2004
    Publication date: October 21, 2004
    Inventors: Michael Bader, Bert Binas, Giuxuan Chai, Fred Faendrich, Detlev Ganten