Patents by Inventor Bert Nolte

Bert Nolte has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heterobicyclic metalloprotease inhibitors
    Patent number: 7713966
    Abstract: The present invention relates generally to azabicyclic containing pharmaceutical agents, and in particular, to azabicyclic metalloprotease inhibiting compounds. More particularly, the present invention provides a new class of azabicyclic MMP-3, MMP-8 and/or MMP-13 inhibiting compounds, which exhibit an increased potency and selectivity in relation to currently known MMP-13, MMP-8 and MMP-3 inhibitors.
    Type: Grant
    Filed: November 20, 2007
    Date of Patent: May 11, 2010
    Assignee: Alantos Pharmaceuticals Holding, Inc.
    Inventors: Christian Gege, Matthias Schneider, Carine Chevrier, Hongbo Deng, Irving Sucholeiki, Brian M. Gallagher, Jr., Michael Bosies, Christoph Steeneck, Xinyuan Wu, Matthias Hochgürtel, Bert Nolte, Arthur Taveras
  • DIPEPTIDYL PEPTIDASE-IV INHIBITORS
    Publication number: 20100009961
    Abstract: The present invention relates generally to pyrrolidine and thiazolidine DPP-IV inhibitor compounds. The present invention also provides synthetic methods for preparation of such compounds, methods of inhibiting DPP-IV using such compounds and pharmaceutical formulations containing them for treatment of DPP-IV mediated diseases, in particular, Type-2 diabetes.
    Type: Application
    Filed: June 26, 2009
    Publication date: January 14, 2010
    Applicant: Alantos Pharmaceuticals Holding, Inc.
    Inventors: Heiko Kroth, Tim Feuerstein, Frank Richter, Jurgen Boer, Michael Essers, Bert Nolte, Matthias Schneider, Matthias Hochguertel, Fritz-Frieder Frickel, Arthur Taveras, Christoph Steeneck
  • Heterobicyclic Metalloprotease Inhibitors
    Publication number: 20090312312
    Abstract: The present invention relates generally to amide group containing pharmaceutical agents, and in particular, to amide containing heterobicyclic metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of heterobicyclic MMP-13 inhibiting and MMP-3 inhibiting compounds, that exhibit an increased potency in relation to currently known MMP-13 and MMP-3 inhibitors.
    Type: Application
    Filed: February 12, 2009
    Publication date: December 17, 2009
    Applicant: ALANTOS PHARMACEUTICALS HOLDING, INC.
    Inventors: Christoph STEENECK, Christian GEGE, Frank RICHTER, Heiko KROTH, Matthias HOCHGURTEL, Michael ESSERS, Joshua VAN VELDHUIZEN, Bert NOLTE, Brian M. GALLAGHER, JR., Tim FEUERSTEIN, Matthias SCHNEIDER, Torsten ARNDT, Hongbo DENG, Ralf BIESINGER, Xinyuan WU, Harald BLUHM, Irving SUCHOLEIKI, Arthur G. TAVERAS
  • (HETERO)ARYL CYCLOHEXANE DERIVATIVES
    Publication number: 20090247573
    Abstract: The invention relates to compounds that have an affinity to the ?-opioid receptor and the ORL 1-receptor, methods for their production, medications containing these compounds and the use of these compounds for the treatment of pain and other conditions.
    Type: Application
    Filed: March 25, 2009
    Publication date: October 1, 2009
    Applicant: GRUNENTHAL GMBH
    Inventors: Saskia Zemolka, Stefan Schunk, Bert Nolte, Klaus Linz, Wolfgang Schroder, Werner Englberger, Hans Schick, Helmut Sonnenschein, Birgitta Henkel, Jozsef Balint
  • SUBSTITUTED SPIROCYCLIC CYCLOHEXANE DERIVATIVES
    Publication number: 20090247561
    Abstract: The invention relates to compounds that have an affinity to the ?-opioid receptor and the ORL 1-receptor, methods for their production, medications containing these compounds and the use of these compounds for the treatment of pain and other conditions.
    Type: Application
    Filed: March 25, 2009
    Publication date: October 1, 2009
    Applicant: Grunenthal GmbH
    Inventors: Saskia Zemolka, Bert Nolte, Sven Frorman, Claudia Hinze, Klaus Linz, Wolfgang Schroder, Werner Englberger, Hans Schick, Helmut Sonnenschein
  • SUBSTITUTED 4-AMINOCYCLOHEXANE DERIVATIVES
    Publication number: 20090247530
    Abstract: The invention relates to compounds that have an affinity to the ?-opioid receptor and the ORL 1-receptor, methods for their production, medications containing these compounds and the use of these compounds for the treatment of pain and other conditions.
    Type: Application
    Filed: March 25, 2009
    Publication date: October 1, 2009
    Applicant: Grunenthal GMBH
    Inventors: Bert NOLTE, Wolfgang SCHRODER, Klaus LINZ, Werner ENGLBERGER, Hans SCHICK, Heinz GRAUBAUM, Birgit ROLOFF, Sigrid OZEGOWSKI, Jozsef BALINT, Helmut SONNENSCHEIN
  • SUBSTITUTED CYCLOHEXYLDIAMINES
    Publication number: 20090247591
    Abstract: The invention relates to compounds that have an affinity to the ?-opioid receptor and the ORL 1-receptor, methods for their production, medications containing these compounds and the use of these compounds for the treatment of pain or other conditions.
    Type: Application
    Filed: March 25, 2009
    Publication date: October 1, 2009
    Applicant: Grunenthal GmbH
    Inventors: Saskia Zemolka, Bert Nolte, Klaus Linz, Derek John Saunders, Wolfgang Schroder, Wemer Englberger, Fritz Theil, Hans Schick, Jens Kaufmann, Julian Gebauer, Helmut Sonnenschein
  • Heterobicyclic metalloprotease inhibitors
    Publication number: 20090137547
    Abstract: The present invention relates generally to amide group containing pharmaceutical agents, and in particular, to amide containing heterobicyclic metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of heterobicyclic MMP-13 inhibiting and MMP-3 inhibiting compounds, that exhibit an increased potency in relation to currently known MMP-13 and MMP-3 inhibitors.
    Type: Application
    Filed: December 7, 2007
    Publication date: May 28, 2009
    Inventors: Christoph Steeneck, Christian Gege, Frank Riohter, Holko Kroth, Mouhlee Hochgueriel, Michael Essors, Joshua Van Veldhulzen, Bert Nolte, Brian M. Gallaghor, JR., Tim Feuerstein, Matthias Schneider, Toralen Arndt, Hongbo Deng, Ralf Blesinger, Xinyuan Wu, Harald Bluhm, Irving Sucholelld, Arthur G. Taverse
  • Heterobicyclic metalloprotease inhibitors
    Publication number: 20080261968
    Abstract: The present invention relates generally to azabicyclic containing pharmaceutical agents, and in particular, to azabicyclic metalloprotease inhibiting compounds. More particularly, the present invention provides a new class of azabicyclic MMP-3, MMP-8 and/or MMP-13 inhibiting compounds, which exhibit an increased potency and selectivity in relation to currently known MMP-13, MMP-8 and MMP-3 inhibitors.
    Type: Application
    Filed: November 20, 2007
    Publication date: October 23, 2008
    Inventors: Christian Gege, Matthias Schneider, Carine Chevrier, Hongbo Deng, Irving Sucholeiki, Brian M. Gallagher, Michael Bosies, Christoph Steeneck, Xinyuan Wu, Matthias Hochgurtel, Bert Nolte, Arthur Taveras
  • Heterobicyclic metalloprotease inhibitors
    Publication number: 20080176870
    Abstract: The present invention relates generally to heterobicyclic containing pharmaceutical agents, and in particular, to heterobicyclic metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of heterobicyclic metalloprotease inhibiting compounds that exhibit an increased potency in relation to currently known metalloprotease inhibitors.
    Type: Application
    Filed: November 20, 2007
    Publication date: July 24, 2008
    Inventors: Bert Nolte, Irving Sucholeiki, Tim Feuerstein, Brian M. Gallagher, Xinyuan Wu, Christoph Steeneck, Christian Gege, Hongbo Deng, Joshua Van Veldhuizen, Arthur Taveras
  • Heterobicyclic metalloprotease inhibitors
    Publication number: 20080161300
    Abstract: The present invention relates generally to amide group containing pharmaceutical agents, and in particular, to amide containing heterobicyclic metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of heterobicyclic MMP-13 inhibiting and MMP-3 inhibiting compounds, that exhibit an increased potency in relation to currently known MMP-13 and MMP-3 inhibitors.
    Type: Application
    Filed: December 7, 2007
    Publication date: July 3, 2008
    Applicant: Alantos Pharmaceuticals Holding, Inc.
    Inventors: Christoph Steeneck, Christian Gege, Frank Richter, Heiko Kroth, Matthias Hochgurtel, Michael Essers, Joshua Van Veldhuizen, Bert Nolte, Brian Gallagher, Tim Feuerstein, Matthias Schneider, Torsten Arndt, Hongbo Deng, Ralf Beisinger, Xinyuan Wu, Harald Bluhm, Irving Sucholeiki, Arthur Taveras
  • Heterobicyclic metalloprotease inhibitors
    Publication number: 20070155738
    Abstract: The present invention relates generally to amide group containing pharmaceutical agents, and in particular, to amide containing heterobicyclic metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of heterobicyclic MMP-13 inhibiting and MMP-3 inhibiting compounds, that exhibit an increased potency in relation to currently known MMP-13 and MMP-3 inhibitors.
    Type: Application
    Filed: November 20, 2006
    Publication date: July 5, 2007
    Inventors: Christoph Steeneck, Christian Gege, Frank Richter, Heiko Kroth, Matthias Hochguertel, Michael Essers, Joshua Van Veldhuizen, Bert Nolte, Brian Gallagher, Tim Feuerstein, Matthias Schneider, Torsten Arndt, Hongbo Deng, Ralf Biesinger, Xinyuan Wu, Harald Bluhm, Irving Sucholeiki, Arthur Taveras
  • Heterobicyclic metalloprotease inhibitors
    Publication number: 20060293345
    Abstract: The present invention relates generally to amide group containing pharmaceutical agents, and in particular, to amide containing heterobicyclic metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of heterobicyclic MMP-13 inhibiting compounds, that exhibit an increased potency in relation to currently known MMP-13 inhibitors.
    Type: Application
    Filed: May 22, 2006
    Publication date: December 28, 2006
    Inventors: Christoph Steeneck, Christian Gege, Frank Richter, Matthias Hochguertel, Tim Feuerstein, Harald Bluhm, Irving Sucholeiki, Jurgen Boer, Xinyuan Wu, Matthias Schneider, Bert Nolte, Brian Gallagher, Joshua Van Veldhuizen, Hongbo Dong, Michael Essers, Heiko Kroth, Andrew Kiely, Timothy Powers, Arthur Taveras
  • Dipeptidyl peptidase-IV inhibitors
    Publication number: 20060270701
    Abstract: The present invention relates generally to pyrrolidine and thiazolidine DPP-IV inhibitor compounds. The present invention also provides synthetic methods for preparation of such compounds, methods of inhibiting DPP-IV using such compounds and pharmaceutical formulations containing them for treatment of DPP-IV mediated diseases, in particular, Type-2 diabetes.
    Type: Application
    Filed: April 21, 2006
    Publication date: November 30, 2006
    Inventors: Heiko Kroth, Tim Feuerstein, Frank Richter, Jurgen Boer, Michael Essers, Bert Nolte, Matthias Schneider, Matthias Hochguertel, Fritz-Frieder Frickel, Arthur Taveras
  • Envelope with an adhesive closure and method and device for producing the same
    Patent number: 6732494
    Abstract: An envelope consisting of a front side and a rear side which are interconnected by side flaps, has a fold-back flap to which a layer of contact adhesive is applied. The adhesive used is a strong contact adhesive which is effective without moistening or activation by any other means. The fold-back flap is laid against the rear side of the envelope for the purposes of transport and storage, an area coated with a parting agent being provided so that the adhesive can be detached before use. The envelope is closed by pressing the otherwise uncoated closing flap onto the adhesive-coated fold-back flap. The adhesive is applied to the fold-back flap by transfer, i.e. the adhesive is applied to the parting agent layer during production and then transferred to the fold-back flap when the latter is redressed.
    Type: Grant
    Filed: September 21, 2001
    Date of Patent: May 11, 2004
    Assignee: Otto Ficker AG
    Inventor: Bert Nolte
  • Process for automatically packaging letter envelopes and mailing wallets into a container and automatic packaging machine for carrying out the process
    Patent number: 4879862
    Abstract: In the process of packaging letter envelopes and mailing wallets, the packaging batch is counted in the end region of the production machine, and the individual article of the packaging batch corresponding to the specific batch size is at least identified or optionally pushed a certain distance sideways out of the path of movement of the packaging batch in one direction or the other as a counting article. The packaging batch is deposited on a conveyor belt and conveyed away. A stack support keeps the stack approximately vertical on its end face. The stack support is advanced in front of the stack at the conveying speed of the conveyor belt. As soon as the counting article at the end of a stack has arrived at a transfer point which is at a relatively long distance from the production machine, a separating device is introduced into the stack, with the result that the following portion of the packaging batch is temporarily halted.
    Type: Grant
    Filed: December 8, 1987
    Date of Patent: November 14, 1989
    Assignee: Otto Ficker AG
    Inventors: Bert Nolte, Siegfried Leonhardt