Patents by Inventor Bertha C. Madras

Bertha C. Madras has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Boat tropanes
    Patent number: 7105678
    Abstract: Radiopharmaceutical compounds are disclosed. A tropane compound is linked through the N atom at the 8-position to a chelating ligand capable of complexing technetium or rhenium to produce a neutral labeled complex that selectively binds to the dopamine transporter over the serotonin transporter with a ratio of 10 or more. These compounds can be prepared as separate diastereoisomers as well as a mixture of diastereoisomers. Also disclosed are radiopharmaceutical kits for preparing the labeled radiopharmaceutical compounds.
    Type: Grant
    Filed: October 11, 2001
    Date of Patent: September 12, 2006
    Assignees: Organix, Inc., President and Fellows of Harvard College, The General Hospital Corporation
    Inventors: Peter C. Meltzer, Paul Blundell, Bertha C. Madras