Patents by Inventor Berthold Szperalski

Berthold Szperalski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for growing mammalian cells in vitro
    Patent number: 7390660
    Abstract: The invention relates to a method for reducing glucose consumption during cultivation of animal cells, which comprises cultivating animal cells in the presence of a bi- or tricarbonic acid or a salt thereof at a concentration of about 1 to 50 mmol/l.
    Type: Grant
    Filed: March 3, 2003
    Date of Patent: June 24, 2008
    Assignee: Hoffman-La Roche Inc.
    Inventors: Ulrich Behrendt, Horst Eberhardt, Berthold Szperalski
  • Hollow fiber membrane module
    Patent number: 7128837
    Abstract: The present invention relates to hollow fiber membrane modules for use as “immersion modules” in filtration and/or dialysis methods, in particular whenever impairments due to fouling effects are expected from the use of liquids that are contaminated or lead to deposits. The hollow fiber membrane module comprises at least one housing and a plurality of tubular hollow fiber membranes which are arranged parallel to one another in and/or around the housing in a packing space, wherein the volumetric ratio of all the hollow fiber membranes arranged in the packing space to the packing space is less than 20%. Methods for producing such hollow fiber membrane modules are also provided.
    Type: Grant
    Filed: February 8, 2006
    Date of Patent: October 31, 2006
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Ulrich Behrendt, Reinhard Gergen, Franz-Josef Gerner, Gerhard Herres, Berthold Szperalski, Eckehard Walitza, Wolfram Weber
  • Hollow fiber membrane module
    Publication number: 20060124531
    Abstract: The present invention relates to hollow fiber membrane modules for use as “immersion modules” in filtration and/or dialysis methods, in particular whenever impairments due to fouling effects are expected from the use of liquids that are contaminated or lead to deposits. The hollow fiber membrane module comprises at least one housing and a plurality of tubular hollow fiber membranes which are arranged parallel to one another in and/or around the housing in a packing space, wherein the volumetric ratio of all the hollow fiber membranes arranged in the packing space to the packing space is less than 20%. Methods for producing such hollow fiber membrane modules are also provided.
    Type: Application
    Filed: February 8, 2006
    Publication date: June 15, 2006
    Inventors: Ulrich Behrendt, Reinhard Gergen, Franz-Josef Gerner, Gerhard Herres, Berthold Szperalski, Eckehard Walitza, Wolfram Weber
  • Methods for growing mammalian cells in vitro
    Publication number: 20030175951
    Abstract: The invention relates to a method for reducing glucose consumption during cultivation of animal cells, which comprises cultivating animal cells in the presence of a bi- or tricarbonic acid or a salt thereof at a concentration of about 1 to 50 mmol/l.
    Type: Application
    Filed: March 3, 2003
    Publication date: September 18, 2003
    Inventors: Ulrich Behrendt, Horst Eberhardt, Berthold Szperalski
  • Hollow fiber membrane module
    Publication number: 20020179516
    Abstract: The present invention relates to hollow fiber membrane modules for use as “immersion modules” in filtration and/or dialysis methods, in particular whenever impairments due to fouling effects are expected from the use of liquids that are contaminated or lead to deposits. The hollow fiber membrane module comprises at least one housing and a plurality of tubular hollow fiber membranes which are arranged parallel to one another in and/or around the housing in a packing space, wherein the volumetric ratio of all the hollow fiber membranes arranged in the packing space to the packing space is less than 20%. Methods for producing such hollow fiber membrane modules are also provided.
    Type: Application
    Filed: February 14, 2002
    Publication date: December 5, 2002
    Inventors: Ulrich Behrendt, Reinhard Gergen, Franz-Josef Gerner, Gerhard Herres, Berthold Szperalski, Eckehard Walitza, Wolfram Weber